Tags

Type your tag names separated by a space and hit enter

[Relation between chronic respiratory diseases in children and secretory IgA and IgM].
Cesk Pediatr. 1990 Feb; 45(2):75-7.CP

Abstract

In 1981-1984 from a total of 288 children aged 6-36 months, suffering from acute and relapsing respiratory disease, in 52 children in the nasopharyngeal secretion IgM was detected in average amounts of 11.3 +/- 9.7 mg/100 ml. In 13 of the children in the course of 1-2 years after the first examination the IgM values in the nasopharyngeal secretion doubled or increased several times (20-50 mg/100 ml). The values in saliva at the age of 5-9 years were in seven of these children lower than the mean physiological values of SIgA in saliva (34.3 +/- 15.9 mg/100 ml). In 12 children in the course of 5-9 years chronic respiratory disease developed--obstructive bronchitis. In six children, where during school age in saliva mean SIgA values lower than normal were recorded, more frequent relapses and complications were recorded (pneumonia, sinobronchial syndrome, otitis media). Elevated values of SIgM in the nasopharyngeal secretion of infants and toddlers with acute and relapsing bronchitis can be considered a risk factor for the development of chronic disease, in particular in case of a permanently reduced SIgA formation also in saliva.

Authors+Show Affiliations

Michalicková J
Centrum pre výzkum zdravia zeny a diet'at'a - oddelenie výskumu zdravia dietata, Bratislava.
Sulko M
No affiliation info available

MeSH

Child, PreschoolChronic DiseaseFemaleHumansImmunoglobulin A, SecretoryImmunoglobulin MInfantMaleNasopharynxRespiratory Tract Diseases

Pub Type(s)

Journal Article

Language

slo

PubMed ID

2208359

Citation

Michalicková, J, and M Sulko. "[Relation Between Chronic Respiratory Diseases in Children and Secretory IgA and IgM]." Ceskoslovenska Pediatrie, vol. 45, no. 2, 1990, pp. 75-7.
Michalicková J, Sulko M. [Relation between chronic respiratory diseases in children and secretory IgA and IgM]. Cesk Pediatr. 1990;45(2):75-7.
Michalicková, J., & Sulko, M. (1990). [Relation between chronic respiratory diseases in children and secretory IgA and IgM]. Ceskoslovenska Pediatrie, 45(2), 75-7.
Michalicková J, Sulko M. [Relation Between Chronic Respiratory Diseases in Children and Secretory IgA and IgM]. Cesk Pediatr. 1990;45(2):75-7. PubMed PMID: 2208359.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Relation between chronic respiratory diseases in children and secretory IgA and IgM]. AU - Michalicková,J, AU - Sulko,M, PY - 1990/2/1/pubmed PY - 1990/2/1/medline PY - 1990/2/1/entrez SP - 75 EP - 7 JF - Ceskoslovenska pediatrie JO - Cesk Pediatr VL - 45 IS - 2 N2 - In 1981-1984 from a total of 288 children aged 6-36 months, suffering from acute and relapsing respiratory disease, in 52 children in the nasopharyngeal secretion IgM was detected in average amounts of 11.3 +/- 9.7 mg/100 ml. In 13 of the children in the course of 1-2 years after the first examination the IgM values in the nasopharyngeal secretion doubled or increased several times (20-50 mg/100 ml). The values in saliva at the age of 5-9 years were in seven of these children lower than the mean physiological values of SIgA in saliva (34.3 +/- 15.9 mg/100 ml). In 12 children in the course of 5-9 years chronic respiratory disease developed--obstructive bronchitis. In six children, where during school age in saliva mean SIgA values lower than normal were recorded, more frequent relapses and complications were recorded (pneumonia, sinobronchial syndrome, otitis media). Elevated values of SIgM in the nasopharyngeal secretion of infants and toddlers with acute and relapsing bronchitis can be considered a risk factor for the development of chronic disease, in particular in case of a permanently reduced SIgA formation also in saliva. SN - 0069-2328 UR - https://www.unboundmedicine.com/medline/citation/2208359/[Relation_between_chronic_respiratory_diseases_in_children_and_secretory_IgA_and_IgM]_ DB - PRIME DP - Unbound Medicine ER -