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Anticandidal activity of the essential oil of Nepeta transcaucasica Grossh.
Chem Biodivers. 2011 Nov; 8(11):2144-8.CB

Abstract

Hydrodistallation of the aerial parts of Nepeta transcaucasica Grossh. (Lamiaceae), collected in Ağrı, Doğubayazıt Province, afforded an essential oil that was characterized by GC and GC/MS analyses. Twenty-seven compounds, representing 97.69% of the total oil composition, were identified, and 4aα,7α,7aβ-nepetalactone (1; 39%), 4aα,7α,7aα-nepetalactone (2; 28%), and germacrene D (3; 15%) constituted the major components. The anticandidal effects of the oil were evaluated against seven Candida strains by using the broth microdilution method. The oil showed good inhibitory effects against C. glabrata and C. tropicalis at minimal inhibitory concentrations (MICs) of 0.09 and 0.375 mg/ml, respectively.

Authors+Show Affiliations

Department of Pharmacognosy, Anadolu University, Faculty of Pharmacy, Eskişehir. giscan@anadolu.edu.trNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

22083927

Citation

Işcan, Gökalp, et al. "Anticandidal Activity of the Essential Oil of Nepeta Transcaucasica Grossh." Chemistry & Biodiversity, vol. 8, no. 11, 2011, pp. 2144-8.
Işcan G, Köse YB, Demirci B, et al. Anticandidal activity of the essential oil of Nepeta transcaucasica Grossh. Chem Biodivers. 2011;8(11):2144-8.
Işcan, G., Köse, Y. B., Demirci, B., & Başer, K. H. (2011). Anticandidal activity of the essential oil of Nepeta transcaucasica Grossh. Chemistry & Biodiversity, 8(11), 2144-8. https://doi.org/10.1002/cbdv.201100091
Işcan G, et al. Anticandidal Activity of the Essential Oil of Nepeta Transcaucasica Grossh. Chem Biodivers. 2011;8(11):2144-8. PubMed PMID: 22083927.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Anticandidal activity of the essential oil of Nepeta transcaucasica Grossh. AU - Işcan,Gökalp, AU - Köse,Y Bülent, AU - Demirci,Betül, AU - Başer,K Hüsnü Can, PY - 2011/11/16/entrez PY - 2011/11/16/pubmed PY - 2012/5/17/medline SP - 2144 EP - 8 JF - Chemistry & biodiversity JO - Chem Biodivers VL - 8 IS - 11 N2 - Hydrodistallation of the aerial parts of Nepeta transcaucasica Grossh. (Lamiaceae), collected in Ağrı, Doğubayazıt Province, afforded an essential oil that was characterized by GC and GC/MS analyses. Twenty-seven compounds, representing 97.69% of the total oil composition, were identified, and 4aα,7α,7aβ-nepetalactone (1; 39%), 4aα,7α,7aα-nepetalactone (2; 28%), and germacrene D (3; 15%) constituted the major components. The anticandidal effects of the oil were evaluated against seven Candida strains by using the broth microdilution method. The oil showed good inhibitory effects against C. glabrata and C. tropicalis at minimal inhibitory concentrations (MICs) of 0.09 and 0.375 mg/ml, respectively. SN - 1612-1880 UR - https://www.unboundmedicine.com/medline/citation/22083927/Anticandidal_activity_of_the_essential_oil_of_Nepeta_transcaucasica_Grossh_ L2 - https://doi.org/10.1002/cbdv.201100091 DB - PRIME DP - Unbound Medicine ER -