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New antioxidant and antiglycation active triterpenoid saponins from the root bark of Aralia taibaiensis.
Fitoterapia. 2012 Jan; 83(1):234-40.F

Abstract

Four new oleanane type triterpenoid saponins (1-4) and a known saponin (5) were isolated from the root bark of Aralia taibaiensis Z.Z. Wang et H.C. Zheng. The structures of the four new compounds were elucidated as 3-O-{β-D-glucopyranosyl-(1→2)-[β-D-glucopyranosyl-(1→3)]-β-D-glucurono-pyranosyl}-olean-11,13(18)-diene-28-oic acid 28-O-β-D-glucopyranosyl ester (1), 3-O-{β-D-gluco-pyranosyl-(1→3)-[α-l-arabinofuranosyl-(1→4)]-β-D-glucuronopyranosyl}-olean-11,13(18)-diene-28-oic acid 28-O-β-D-glucopyranosyl ester (2), 3-O-{β-d-glucopyranosyl-(1→2)-[α-l-arabinofuranosyl-(1→4)]-β-D-glucuronopyranosyl}-oleanolic acid 28-O-β-D-glucopyranosyl ester (3) and 3-O-{β-D-glucopyranosyl-(1→2)-[β-D-glucopyranosyl-(1→3)]-β-D-glucuronopyranosyl}-oleanolic acid 28-O-β-D-glucopyranosyl ester (4), on the basis of extensive spectral analysis and chemical evidence. Compounds 1-5 exhibited moderate effects on antioxidant and antiglycation activities, which correlated with treatment of diabetes mellitus.

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Authors+Show Affiliations

Bi L
Institute of Materia Medica, School of Pharmacy, Fourth Military Medical University, Xi'an 710032, PR China.
Tian X
No affiliation info available
Dou F
No affiliation info available
Hong L
No affiliation info available
Tang H
No affiliation info available
Wang S
No affiliation info available

MeSH

AntioxidantsAraliaMolecular StructurePlant BarkPlant RootsSaponinsTriterpenes

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

22088497

Citation

Bi, Linlin, et al. "New Antioxidant and Antiglycation Active Triterpenoid Saponins From the Root Bark of Aralia Taibaiensis." Fitoterapia, vol. 83, no. 1, 2012, pp. 234-40.
Bi L, Tian X, Dou F, et al. New antioxidant and antiglycation active triterpenoid saponins from the root bark of Aralia taibaiensis. Fitoterapia. 2012;83(1):234-40.
Bi, L., Tian, X., Dou, F., Hong, L., Tang, H., & Wang, S. (2012). New antioxidant and antiglycation active triterpenoid saponins from the root bark of Aralia taibaiensis. Fitoterapia, 83(1), 234-40. https://doi.org/10.1016/j.fitote.2011.11.002
Bi L, et al. New Antioxidant and Antiglycation Active Triterpenoid Saponins From the Root Bark of Aralia Taibaiensis. Fitoterapia. 2012;83(1):234-40. PubMed PMID: 22088497.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - New antioxidant and antiglycation active triterpenoid saponins from the root bark of Aralia taibaiensis. AU - Bi,Linlin, AU - Tian,Xiangrong, AU - Dou,Fang, AU - Hong,Liangjian, AU - Tang,Haifeng, AU - Wang,Siwang, Y1 - 2011/11/09/ PY - 2011/08/31/received PY - 2011/10/25/revised PY - 2011/11/01/accepted PY - 2011/11/18/entrez PY - 2011/11/18/pubmed PY - 2012/4/27/medline SP - 234 EP - 40 JF - Fitoterapia JO - Fitoterapia VL - 83 IS - 1 N2 - Four new oleanane type triterpenoid saponins (1-4) and a known saponin (5) were isolated from the root bark of Aralia taibaiensis Z.Z. Wang et H.C. Zheng. The structures of the four new compounds were elucidated as 3-O-{β-D-glucopyranosyl-(1→2)-[β-D-glucopyranosyl-(1→3)]-β-D-glucurono-pyranosyl}-olean-11,13(18)-diene-28-oic acid 28-O-β-D-glucopyranosyl ester (1), 3-O-{β-D-gluco-pyranosyl-(1→3)-[α-l-arabinofuranosyl-(1→4)]-β-D-glucuronopyranosyl}-olean-11,13(18)-diene-28-oic acid 28-O-β-D-glucopyranosyl ester (2), 3-O-{β-d-glucopyranosyl-(1→2)-[α-l-arabinofuranosyl-(1→4)]-β-D-glucuronopyranosyl}-oleanolic acid 28-O-β-D-glucopyranosyl ester (3) and 3-O-{β-D-glucopyranosyl-(1→2)-[β-D-glucopyranosyl-(1→3)]-β-D-glucuronopyranosyl}-oleanolic acid 28-O-β-D-glucopyranosyl ester (4), on the basis of extensive spectral analysis and chemical evidence. Compounds 1-5 exhibited moderate effects on antioxidant and antiglycation activities, which correlated with treatment of diabetes mellitus. SN - 1873-6971 UR - https://www.unboundmedicine.com/medline/citation/22088497/New_antioxidant_and_antiglycation_active_triterpenoid_saponins_from_the_root_bark_of_Aralia_taibaiensis_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0367-326X(11)00278-4 DB - PRIME DP - Unbound Medicine ER -