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Hydration measurements of the stratum corneum: comparison between the capacitance method (digital version of the Corneometer CM 825®) and the impedance method (Skicon-200EX®).
Skin Res Technol. 2012 Aug; 18(3):316-23.SR

Abstract

BACKGROUND

Measurement of stratum corneum (SC) hydration often involves the use of commercial instruments. The aim of this study was to compare and validate two recent instruments: the Corneometer 825® (digital probe) and the Skicon-200 EX®.

METHODS

In vitro calibration was carried out on filter pads using different solvents, measurements over different layers of plastic foils, and evaluation of desorption kinetics. In vivo measurements were carried out on skin sites covering a range of very dry to well-hydrated skin areas.

RESULTS

Conductance measurements are influenced by electrolytes while capacitance measurements are not. Dielectric constant of the solvents influences the values of both instruments (r respectively 0.92 and 0.99). The capacitance method carries information from deeper layers (up to 45 μm) compared with the conductance instrument (up to 15 μm). Desorption experiments show a strong relation between the amount of water and respectively the capacitance and the conductance values. The in vivo experiments revealed a strong relation between the two methods (r = 0.97). Sensitivity of the capacitance method is limited for the highest hydration values.

CONCLUSIONS

Both instruments allow a certain calibration and both give good estimates of the SC hydration.

Authors+Show Affiliations

Department of Human Biometry and Biomechanics, Faculty of Physical Education and Physiotherapy, Vrije Universiteit Brussel, Brussels, Belgium. pclarys@vub.ac.beNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Evaluation Study
Journal Article

Language

eng

PubMed ID

22092664

Citation

Clarys, Peter, et al. "Hydration Measurements of the Stratum Corneum: Comparison Between the Capacitance Method (digital Version of the Corneometer CM 825®) and the Impedance Method (Skicon-200EX®)." Skin Research and Technology : Official Journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI), vol. 18, no. 3, 2012, pp. 316-23.
Clarys P, Clijsen R, Taeymans J, et al. Hydration measurements of the stratum corneum: comparison between the capacitance method (digital version of the Corneometer CM 825®) and the impedance method (Skicon-200EX®). Skin Res Technol. 2012;18(3):316-23.
Clarys, P., Clijsen, R., Taeymans, J., & Barel, A. O. (2012). Hydration measurements of the stratum corneum: comparison between the capacitance method (digital version of the Corneometer CM 825®) and the impedance method (Skicon-200EX®). Skin Research and Technology : Official Journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI), 18(3), 316-23. https://doi.org/10.1111/j.1600-0846.2011.00573.x
Clarys P, et al. Hydration Measurements of the Stratum Corneum: Comparison Between the Capacitance Method (digital Version of the Corneometer CM 825®) and the Impedance Method (Skicon-200EX®). Skin Res Technol. 2012;18(3):316-23. PubMed PMID: 22092664.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Hydration measurements of the stratum corneum: comparison between the capacitance method (digital version of the Corneometer CM 825®) and the impedance method (Skicon-200EX®). AU - Clarys,Peter, AU - Clijsen,Ron, AU - Taeymans,Jan, AU - Barel,André O, Y1 - 2011/08/24/ PY - 2011/07/07/accepted PY - 2011/11/19/entrez PY - 2011/11/19/pubmed PY - 2012/12/10/medline SP - 316 EP - 23 JF - Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) JO - Skin Res Technol VL - 18 IS - 3 N2 - BACKGROUND: Measurement of stratum corneum (SC) hydration often involves the use of commercial instruments. The aim of this study was to compare and validate two recent instruments: the Corneometer 825® (digital probe) and the Skicon-200 EX®. METHODS: In vitro calibration was carried out on filter pads using different solvents, measurements over different layers of plastic foils, and evaluation of desorption kinetics. In vivo measurements were carried out on skin sites covering a range of very dry to well-hydrated skin areas. RESULTS: Conductance measurements are influenced by electrolytes while capacitance measurements are not. Dielectric constant of the solvents influences the values of both instruments (r respectively 0.92 and 0.99). The capacitance method carries information from deeper layers (up to 45 μm) compared with the conductance instrument (up to 15 μm). Desorption experiments show a strong relation between the amount of water and respectively the capacitance and the conductance values. The in vivo experiments revealed a strong relation between the two methods (r = 0.97). Sensitivity of the capacitance method is limited for the highest hydration values. CONCLUSIONS: Both instruments allow a certain calibration and both give good estimates of the SC hydration. SN - 1600-0846 UR - https://www.unboundmedicine.com/medline/citation/22092664/Hydration_measurements_of_the_stratum_corneum:_comparison_between_the_capacitance_method__digital_version_of_the_Corneometer_CM_825®__and_the_impedance_method__Skicon_200EX®__ L2 - https://doi.org/10.1111/j.1600-0846.2011.00573.x DB - PRIME DP - Unbound Medicine ER -