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Advances in pediatric nonalcoholic fatty liver disease.
Pediatr Clin North Am. 2011 Dec; 58(6):1375-92, x.PC

Abstract

Nonalcoholic fatty liver disease (NAFLD) has emerged as the most common cause of pediatric liver disease in the developed world. Children have a form of NAFLD that is pathologically distinct from adults. Although NAFLD remains a pathologic diagnosis, biomarkers and imaging studies hold promise as noninvasive means of both establishing the diagnosis and following the disease course. Significant advancements have recently been made in genetics, pathophysiology, and the treatment of NAFLD. The purpose of this article is to provide a clinically relevant review of pediatric NAFLD with an emphasis on recent developments in the field.

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Authors+Show Affiliations

Mencin AA
Division of Pediatric Gastroenterology, Hepatology and Nutrition, Columbia University, 3959 Broadway, CHN 702, New York, NY 10032, USA. jl3553@columbia.edu
Lavine JE
No affiliation info available

MeSH

AdolescentBiomarkersChildComorbidityDiagnostic ImagingFatty LiverGenetic Predisposition to DiseaseHumansLife StyleNon-alcoholic Fatty Liver DiseaseObesityPrevalenceUnited StatesWeight Loss

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Review

Language

eng

PubMed ID

22093857

Citation

Mencin, Ali A., and Joel E. Lavine. "Advances in Pediatric Nonalcoholic Fatty Liver Disease." Pediatric Clinics of North America, vol. 58, no. 6, 2011, pp. 1375-92, x.
Mencin AA, Lavine JE. Advances in pediatric nonalcoholic fatty liver disease. Pediatr Clin North Am. 2011;58(6):1375-92, x.
Mencin, A. A., & Lavine, J. E. (2011). Advances in pediatric nonalcoholic fatty liver disease. Pediatric Clinics of North America, 58(6), 1375-92, x. https://doi.org/10.1016/j.pcl.2011.09.005
Mencin AA, Lavine JE. Advances in Pediatric Nonalcoholic Fatty Liver Disease. Pediatr Clin North Am. 2011;58(6):1375-92, x. PubMed PMID: 22093857.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Advances in pediatric nonalcoholic fatty liver disease. AU - Mencin,Ali A, AU - Lavine,Joel E, Y1 - 2011/10/14/ PY - 2011/11/19/entrez PY - 2011/11/19/pubmed PY - 2012/1/14/medline SP - 1375-92, x JF - Pediatric clinics of North America JO - Pediatr Clin North Am VL - 58 IS - 6 N2 - Nonalcoholic fatty liver disease (NAFLD) has emerged as the most common cause of pediatric liver disease in the developed world. Children have a form of NAFLD that is pathologically distinct from adults. Although NAFLD remains a pathologic diagnosis, biomarkers and imaging studies hold promise as noninvasive means of both establishing the diagnosis and following the disease course. Significant advancements have recently been made in genetics, pathophysiology, and the treatment of NAFLD. The purpose of this article is to provide a clinically relevant review of pediatric NAFLD with an emphasis on recent developments in the field. SN - 1557-8240 UR - https://www.unboundmedicine.com/medline/citation/22093857/Advances_in_pediatric_nonalcoholic_fatty_liver_disease_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0031-3955(11)00109-X DB - PRIME DP - Unbound Medicine ER -