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[Study on the distribution and characteristics of Chinese medicine syndrome in patients with nonalcoholic fatty liver disease].
Zhongguo Zhong Xi Yi Jie He Za Zhi. 2011 Oct; 31(10):1332-6.ZZ

Abstract

OBJECTIVE

To supply evidence for establishing the standard for Chinese medicine (CM) syndrome differentiation by investigating the distribution and characteristics of CM syndromes in patients with nonalcoholic fatty liver disease (NAFLD).

METHODS

928 NAFLD patients' symptoms, signs, tongue and pulse parameters were studied by clinical epidemiologic survey. And the results were analyzed by the cluster analysis and factor analysis.

RESULTS

The results of cluster analysis showed that the CM syndrome typings of fatty liver patients were mainly classified as dampness heat accumulation, Pi deficiency with dampness phlegm, Gan-qi stagnation and Pi deficiency, phlegm stasis accumulation, and Gan-Shen insufficiency, which were in accordance with clinical practice. The results of factor analysis indicated that overweight/obesity, abdominal distension, hypochondriac pain, discomfort in the hepatic region were common "condition factors" of fatty liver patients. The 5 "syndrome factors" such as dampness heat accumulation, Pi deficiency with dampness phlegm, Gan-qi stagnation and Pi deficiency, phlegm stasis accumulation, and Gan-Shen insufficiency showed identification significance in syndrome typing.

CONCLUSIONS

The basic CM syndrome typings of NAFLD were dampness heat accumulation, Pi deficiency with dampness phlegm, Gan-qi stagnation and Pi deficiency, phlegm stasis accumulation, and Gan-Shen insufficiency. The four parameters of fatty liver patients could be classified by statistical analysis as condition factors and syndrome factors (which could reflect CM syndrome characteristics), which could provide certain evidence for establishing CM syndrome differentiation standards.

Authors+Show Affiliations

Department of Traditional Chinese Medicine, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou. fxf68@hotmail.comNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article
Research Support, U.S. Gov't, Non-P.H.S.

Language

chi

PubMed ID

22097199

Citation

Fan, Xiao-fen, et al. "[Study On the Distribution and Characteristics of Chinese Medicine Syndrome in Patients With Nonalcoholic Fatty Liver Disease]." Zhongguo Zhong Xi Yi Jie He Za Zhi Zhongguo Zhongxiyi Jiehe Zazhi = Chinese Journal of Integrated Traditional and Western Medicine, vol. 31, no. 10, 2011, pp. 1332-6.
Fan XF, Deng YQ, Wu GL. [Study on the distribution and characteristics of Chinese medicine syndrome in patients with nonalcoholic fatty liver disease]. Zhongguo Zhong Xi Yi Jie He Za Zhi. 2011;31(10):1332-6.
Fan, X. F., Deng, Y. Q., & Wu, G. L. (2011). [Study on the distribution and characteristics of Chinese medicine syndrome in patients with nonalcoholic fatty liver disease]. Zhongguo Zhong Xi Yi Jie He Za Zhi Zhongguo Zhongxiyi Jiehe Zazhi = Chinese Journal of Integrated Traditional and Western Medicine, 31(10), 1332-6.
Fan XF, Deng YQ, Wu GL. [Study On the Distribution and Characteristics of Chinese Medicine Syndrome in Patients With Nonalcoholic Fatty Liver Disease]. Zhongguo Zhong Xi Yi Jie He Za Zhi. 2011;31(10):1332-6. PubMed PMID: 22097199.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Study on the distribution and characteristics of Chinese medicine syndrome in patients with nonalcoholic fatty liver disease]. AU - Fan,Xiao-fen, AU - Deng,Yin-quan, AU - Wu,Guo-lin, PY - 2011/11/22/entrez PY - 2011/11/22/pubmed PY - 2013/8/2/medline SP - 1332 EP - 6 JF - Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine JO - Zhongguo Zhong Xi Yi Jie He Za Zhi VL - 31 IS - 10 N2 - OBJECTIVE: To supply evidence for establishing the standard for Chinese medicine (CM) syndrome differentiation by investigating the distribution and characteristics of CM syndromes in patients with nonalcoholic fatty liver disease (NAFLD). METHODS: 928 NAFLD patients' symptoms, signs, tongue and pulse parameters were studied by clinical epidemiologic survey. And the results were analyzed by the cluster analysis and factor analysis. RESULTS: The results of cluster analysis showed that the CM syndrome typings of fatty liver patients were mainly classified as dampness heat accumulation, Pi deficiency with dampness phlegm, Gan-qi stagnation and Pi deficiency, phlegm stasis accumulation, and Gan-Shen insufficiency, which were in accordance with clinical practice. The results of factor analysis indicated that overweight/obesity, abdominal distension, hypochondriac pain, discomfort in the hepatic region were common "condition factors" of fatty liver patients. The 5 "syndrome factors" such as dampness heat accumulation, Pi deficiency with dampness phlegm, Gan-qi stagnation and Pi deficiency, phlegm stasis accumulation, and Gan-Shen insufficiency showed identification significance in syndrome typing. CONCLUSIONS: The basic CM syndrome typings of NAFLD were dampness heat accumulation, Pi deficiency with dampness phlegm, Gan-qi stagnation and Pi deficiency, phlegm stasis accumulation, and Gan-Shen insufficiency. The four parameters of fatty liver patients could be classified by statistical analysis as condition factors and syndrome factors (which could reflect CM syndrome characteristics), which could provide certain evidence for establishing CM syndrome differentiation standards. SN - 1003-5370 UR - https://www.unboundmedicine.com/medline/citation/22097199/[Study_on_the_distribution_and_characteristics_of_Chinese_medicine_syndrome_in_patients_with_nonalcoholic_fatty_liver_disease]_ DB - PRIME DP - Unbound Medicine ER -