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Effect of daily consumption of probiotic yoghurt on lipid profiles in pregnant women: a randomized controlled clinical trial.
J Matern Fetal Neonatal Med 2012; 25(9):1552-6JM

Abstract

BACKGROUND

Due to enhanced fat storage primarily during the mid-pregnancy period, pregnancy is associated with elevated levels of lipid profiles. To our knowledge, no reports are available indicating the effects of probiotic yoghurt consumption on serum lipid profiles in pregnant women.

OBJECTIVE

This study was designed to determine the effects of daily consumption of probiotic yoghurt on lipid profiles of Iranian pregnant women.

METHODS

This randomized single-blinded controlled clinical trial was performed among 70 pregnant women, primigravida, aged 18-30 years old who were carrying singleton pregnancy at their third trimester. Subjects were randomly assigned to consume 200 g/d of conventional (n=33) or the probiotic group (n=37) for 9 weeks. The probiotic yoghurt was a commercially available product prepared with the starter cultures of Streptococcus thermophilus and Lactobacillus bulgaricus, enriched with probiotic culture of two strains of lactobacilli (Lactobacillus acidophilus LA5) and bifidobacteria (Bifidobacterium animalis BB12) with a total of min 1 × 10(7) colony-forming units. The conventional yoghurt contained the starter cultures of S. thermophilus and L. bulgaricus. Fasting blood samples were taken at baseline and after 9-weeks intervention to measure serum lipid profiles.

RESULTS

Although consumption of probiotic yogurt for 9 weeks had been resulted in a significant reduction in serum total- (-53.7 mg/dL, p=0.001), LDL- (-35.2 mg/dL, p=0.006) and HDL-cholesterol levels (-9.8 mg/dL, p=0.002) as well as serum triglyceride concentrations (-42.8 mg/dL, p=0.029), no significant differences were found comparing probiotic and conventional yogurts in terms of their effect on serum lipid profiles. Within-Group differences in conventional yogurt group revealed a significant reduction in HDL-cholesterol levels (-8.4 mg/dL, p=0.005) and borderline significant reduction in serum total cholesterol concentrations (-21.6 mg/dL, p=0.08).

CONCLUSION

In conclusion, consumption of probiotic yogurt among pregnant women could not affect serum lipid profiles as compared to the conventional yogurt.

Authors+Show Affiliations

Department of Biochemistry and Nutrition, School of Medicine, Kashan University of Medical Sciences, Iran.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

22098090

Citation

Asemi, Zatollah, et al. "Effect of Daily Consumption of Probiotic Yoghurt On Lipid Profiles in Pregnant Women: a Randomized Controlled Clinical Trial." The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, vol. 25, no. 9, 2012, pp. 1552-6.
Asemi Z, Samimi M, Tabasi Z, et al. Effect of daily consumption of probiotic yoghurt on lipid profiles in pregnant women: a randomized controlled clinical trial. J Matern Fetal Neonatal Med. 2012;25(9):1552-6.
Asemi, Z., Samimi, M., Tabasi, Z., Talebian, P., Azarbad, Z., Hydarzadeh, Z., & Esmaillzadeh, A. (2012). Effect of daily consumption of probiotic yoghurt on lipid profiles in pregnant women: a randomized controlled clinical trial. The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 25(9), pp. 1552-6. doi:10.3109/14767058.2011.640372.
Asemi Z, et al. Effect of Daily Consumption of Probiotic Yoghurt On Lipid Profiles in Pregnant Women: a Randomized Controlled Clinical Trial. J Matern Fetal Neonatal Med. 2012;25(9):1552-6. PubMed PMID: 22098090.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Effect of daily consumption of probiotic yoghurt on lipid profiles in pregnant women: a randomized controlled clinical trial. AU - Asemi,Zatollah, AU - Samimi,Mansoreh, AU - Tabasi,Zohreh, AU - Talebian,Parisa, AU - Azarbad,Zohreh, AU - Hydarzadeh,Zahra, AU - Esmaillzadeh,Ahmad, Y1 - 2011/12/13/ PY - 2011/11/22/entrez PY - 2011/11/22/pubmed PY - 2013/1/18/medline SP - 1552 EP - 6 JF - The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians JO - J. Matern. Fetal. Neonatal. Med. VL - 25 IS - 9 N2 - BACKGROUND: Due to enhanced fat storage primarily during the mid-pregnancy period, pregnancy is associated with elevated levels of lipid profiles. To our knowledge, no reports are available indicating the effects of probiotic yoghurt consumption on serum lipid profiles in pregnant women. OBJECTIVE: This study was designed to determine the effects of daily consumption of probiotic yoghurt on lipid profiles of Iranian pregnant women. METHODS: This randomized single-blinded controlled clinical trial was performed among 70 pregnant women, primigravida, aged 18-30 years old who were carrying singleton pregnancy at their third trimester. Subjects were randomly assigned to consume 200 g/d of conventional (n=33) or the probiotic group (n=37) for 9 weeks. The probiotic yoghurt was a commercially available product prepared with the starter cultures of Streptococcus thermophilus and Lactobacillus bulgaricus, enriched with probiotic culture of two strains of lactobacilli (Lactobacillus acidophilus LA5) and bifidobacteria (Bifidobacterium animalis BB12) with a total of min 1 × 10(7) colony-forming units. The conventional yoghurt contained the starter cultures of S. thermophilus and L. bulgaricus. Fasting blood samples were taken at baseline and after 9-weeks intervention to measure serum lipid profiles. RESULTS: Although consumption of probiotic yogurt for 9 weeks had been resulted in a significant reduction in serum total- (-53.7 mg/dL, p=0.001), LDL- (-35.2 mg/dL, p=0.006) and HDL-cholesterol levels (-9.8 mg/dL, p=0.002) as well as serum triglyceride concentrations (-42.8 mg/dL, p=0.029), no significant differences were found comparing probiotic and conventional yogurts in terms of their effect on serum lipid profiles. Within-Group differences in conventional yogurt group revealed a significant reduction in HDL-cholesterol levels (-8.4 mg/dL, p=0.005) and borderline significant reduction in serum total cholesterol concentrations (-21.6 mg/dL, p=0.08). CONCLUSION: In conclusion, consumption of probiotic yogurt among pregnant women could not affect serum lipid profiles as compared to the conventional yogurt. SN - 1476-4954 UR - https://www.unboundmedicine.com/medline/citation/22098090/Effect_of_daily_consumption_of_probiotic_yoghurt_on_lipid_profiles_in_pregnant_women:_a_randomized_controlled_clinical_trial_ L2 - http://www.tandfonline.com/doi/full/10.3109/14767058.2011.640372 DB - PRIME DP - Unbound Medicine ER -