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Autonomic neuropathy in non-insulin-dependent diabetic patients: correlation with age, sex, duration and metabolic control of diabetes.
Diabete Metab. 1990 May-Jun; 16(3):200-6.DM

Abstract

The aim of this study has been to assess the prevalence of autonomic neuropathy among non-insulin dependent diabetic patients, and to determine whether a correlation could be found between autonomic impairment and the following: age, sex, duration of diabetes, body mass and metabolic control. Two hundred and twenty one non-insulin dependent patients were submitted to four cardiovascular tests: heart rate response to deep breathing and to standing up; blood pressure response to handgrip and to standing up. Sixty six percent of patients showed at least one abnormal cardiovascular response. The prevalence of autonomic impairment was higher in non-insulin dependent than in insulin-dependent diabetics. Patients were grouped according to the extent of autonomic impairment: absent (33.5%), early (27.6%), definite (3.6%), severe (4.5%). An atypical pattern (abnormality of blood pressure responses in absence of a definite abnormality of heart rate responses) was found in 30.8% of patients. Heart rate responses correlated significantly with age (p less than 0.001). No correlation between test results and duration was found in the multivariate analysis. The tests' results did not correlate with metabolic control or body mass index. Patients with symptoms of autonomic neuropathy had values for heart rate response to deep breathing and to standing significantly lower than those without (p less than 0.05).

Authors+Show Affiliations

Dipartimento di Medicina ed Oncologia sperimentale, Università di Torino, Italy.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

2210014

Citation

Veglio, M, et al. "Autonomic Neuropathy in Non-insulin-dependent Diabetic Patients: Correlation With Age, Sex, Duration and Metabolic Control of Diabetes." Diabete & Metabolisme, vol. 16, no. 3, 1990, pp. 200-6.
Veglio M, Carpano-Maglioli P, Tonda L, et al. Autonomic neuropathy in non-insulin-dependent diabetic patients: correlation with age, sex, duration and metabolic control of diabetes. Diabete Metab. 1990;16(3):200-6.
Veglio, M., Carpano-Maglioli, P., Tonda, L., Quadri, R., Giannella, R., Rosa, C., & Fonzo, D. (1990). Autonomic neuropathy in non-insulin-dependent diabetic patients: correlation with age, sex, duration and metabolic control of diabetes. Diabete & Metabolisme, 16(3), 200-6.
Veglio M, et al. Autonomic Neuropathy in Non-insulin-dependent Diabetic Patients: Correlation With Age, Sex, Duration and Metabolic Control of Diabetes. Diabete Metab. 1990 May-Jun;16(3):200-6. PubMed PMID: 2210014.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Autonomic neuropathy in non-insulin-dependent diabetic patients: correlation with age, sex, duration and metabolic control of diabetes. AU - Veglio,M, AU - Carpano-Maglioli,P, AU - Tonda,L, AU - Quadri,R, AU - Giannella,R, AU - Rosa,C, AU - Fonzo,D, PY - 1990/5/1/pubmed PY - 2000/3/11/medline PY - 1990/5/1/entrez SP - 200 EP - 6 JF - Diabete & metabolisme JO - Diabete Metab VL - 16 IS - 3 N2 - The aim of this study has been to assess the prevalence of autonomic neuropathy among non-insulin dependent diabetic patients, and to determine whether a correlation could be found between autonomic impairment and the following: age, sex, duration of diabetes, body mass and metabolic control. Two hundred and twenty one non-insulin dependent patients were submitted to four cardiovascular tests: heart rate response to deep breathing and to standing up; blood pressure response to handgrip and to standing up. Sixty six percent of patients showed at least one abnormal cardiovascular response. The prevalence of autonomic impairment was higher in non-insulin dependent than in insulin-dependent diabetics. Patients were grouped according to the extent of autonomic impairment: absent (33.5%), early (27.6%), definite (3.6%), severe (4.5%). An atypical pattern (abnormality of blood pressure responses in absence of a definite abnormality of heart rate responses) was found in 30.8% of patients. Heart rate responses correlated significantly with age (p less than 0.001). No correlation between test results and duration was found in the multivariate analysis. The tests' results did not correlate with metabolic control or body mass index. Patients with symptoms of autonomic neuropathy had values for heart rate response to deep breathing and to standing significantly lower than those without (p less than 0.05). SN - 0338-1684 UR - https://www.unboundmedicine.com/medline/citation/2210014/Autonomic_neuropathy_in_non_insulin_dependent_diabetic_patients:_correlation_with_age_sex_duration_and_metabolic_control_of_diabetes_ L2 - https://www.diseaseinfosearch.org/result/2236 DB - PRIME DP - Unbound Medicine ER -