Tags

Type your tag names separated by a space and hit enter

Efficacy of enzymatic debridement of deeply burned hands.
Burns 2012; 38(1):108-12B

Abstract

BACKGROUND

The burned hand is a common and difficult to care-for entity in the field of burns. Due to the anatomy of the hand (important and delicate structures crowded in a small limited space without sub-dermal soft tissue), surgical debridement of the burned tissue is technically difficult and may cause considerable complications and, therefore, should be performed judiciously. Selective enzymatic debridement of the burn wound can preserve the spontaneous epithelialisation potential and reduce the added injury to the traumatised tissue added by a surgical debridement.

OBJECTIVE

The aim of the study was to assess the implication of a selective enzymatic compound (Debrase(®) - Ds) in the special field of deep hand burns, by comparing the actual burn area that required surgical coverage after enzymatic debridement to the burn area clinically judged to require skin grafting prior to debridement.

MATERIALS AND METHODS

This was a retrospective data collection and analysis from 154 complete files of prospective, open-label study in 275 hospitalised, Ds-treated burn patients.

RESULTS

A total of 69 hand burns diagnosed as 'deep' was analysed; 36% of the wounds required surgical intervention after enzymatic debridement; 28.6% of the total burned area estimated initially as deep was covered by skin graft (statistically significant p<0.001).

CONCLUSION

Debridement of deep-hand burns with a selective enzymatic agent decreased the perceived full-thickness wound area and skin-graft use.

Authors+Show Affiliations

Department of Plastic Surgery, Soroka University Medical Center, The Ben-Gurion University of the Negev, 8 Irus Street, Omer 84965, Beer Sheva, Israel. yuvalkr@bgu.ac.ilNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

22103988

Citation

Krieger, Yuval, et al. "Efficacy of Enzymatic Debridement of Deeply Burned Hands." Burns : Journal of the International Society for Burn Injuries, vol. 38, no. 1, 2012, pp. 108-12.
Krieger Y, Bogdanov-Berezovsky A, Gurfinkel R, et al. Efficacy of enzymatic debridement of deeply burned hands. Burns. 2012;38(1):108-12.
Krieger, Y., Bogdanov-Berezovsky, A., Gurfinkel, R., Silberstein, E., Sagi, A., & Rosenberg, L. (2012). Efficacy of enzymatic debridement of deeply burned hands. Burns : Journal of the International Society for Burn Injuries, 38(1), pp. 108-12. doi:10.1016/j.burns.2011.06.002.
Krieger Y, et al. Efficacy of Enzymatic Debridement of Deeply Burned Hands. Burns. 2012;38(1):108-12. PubMed PMID: 22103988.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Efficacy of enzymatic debridement of deeply burned hands. AU - Krieger,Yuval, AU - Bogdanov-Berezovsky,Alexander, AU - Gurfinkel,Reuven, AU - Silberstein,Eldad, AU - Sagi,Amiram, AU - Rosenberg,Lior, Y1 - 2011/11/21/ PY - 2010/01/09/received PY - 2011/05/28/revised PY - 2011/06/14/accepted PY - 2011/11/23/entrez PY - 2011/11/23/pubmed PY - 2012/3/10/medline SP - 108 EP - 12 JF - Burns : journal of the International Society for Burn Injuries JO - Burns VL - 38 IS - 1 N2 - BACKGROUND: The burned hand is a common and difficult to care-for entity in the field of burns. Due to the anatomy of the hand (important and delicate structures crowded in a small limited space without sub-dermal soft tissue), surgical debridement of the burned tissue is technically difficult and may cause considerable complications and, therefore, should be performed judiciously. Selective enzymatic debridement of the burn wound can preserve the spontaneous epithelialisation potential and reduce the added injury to the traumatised tissue added by a surgical debridement. OBJECTIVE: The aim of the study was to assess the implication of a selective enzymatic compound (Debrase(®) - Ds) in the special field of deep hand burns, by comparing the actual burn area that required surgical coverage after enzymatic debridement to the burn area clinically judged to require skin grafting prior to debridement. MATERIALS AND METHODS: This was a retrospective data collection and analysis from 154 complete files of prospective, open-label study in 275 hospitalised, Ds-treated burn patients. RESULTS: A total of 69 hand burns diagnosed as 'deep' was analysed; 36% of the wounds required surgical intervention after enzymatic debridement; 28.6% of the total burned area estimated initially as deep was covered by skin graft (statistically significant p<0.001). CONCLUSION: Debridement of deep-hand burns with a selective enzymatic agent decreased the perceived full-thickness wound area and skin-graft use. SN - 1879-1409 UR - https://www.unboundmedicine.com/medline/citation/22103988/Efficacy_of_enzymatic_debridement_of_deeply_burned_hands_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0305-4179(11)00183-5 DB - PRIME DP - Unbound Medicine ER -