Tags

Type your tag names separated by a space and hit enter

Mutations in rice (Oryza sativa) heavy metal ATPase 2 (OsHMA2) restrict the translocation of zinc and cadmium.
Plant Cell Physiol. 2012 Jan; 53(1):213-24.PC

Abstract

Widespread soil contamination with heavy metals has fostered the need for plant breeders to develop new crops that do not accumulate heavy metals. Metal-transporting transmembrane proteins that transport heavy metals across the plant plasma membrane are key targets for developing these new crops. Oryza sativa heavy metal ATPase 3 (OsHMA3) is known to be a useful gene for limiting cadmium (Cd) accumulation in rice. OsHMA2 is a close homolog of OsHMA3, but the function of OsHMA2 is unknown. To gain insight into the function of OsHMA2, we analyzed three Tos17 insertion mutants. The translocation ratios of zinc (Zn) and Cd were clearly lower in all mutants than in the wild type, suggesting that OsHMA2 is a major transporter of Zn and Cd from roots to shoots. By comparing each allele in the OsHMA2 protein structure and measuring the Cd translocation ratio, we identified the C-terminal region as essential for Cd translocation into shoots. Two alleles were identified as good material for breeding rice that does not contain Cd in the grain but does contain some Zn, and that grows normally.

Authors+Show Affiliations

Department of Biological Production, Faculty of Bioresource Sciences, Akita Prefectural University, Shimoshinjyo-Nakano, Akita, Japan. satohnagasawa@akita-pu.ac.jpNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

22123790

Citation

Satoh-Nagasawa, Namiko, et al. "Mutations in Rice (Oryza Sativa) Heavy Metal ATPase 2 (OsHMA2) Restrict the Translocation of Zinc and Cadmium." Plant & Cell Physiology, vol. 53, no. 1, 2012, pp. 213-24.
Satoh-Nagasawa N, Mori M, Nakazawa N, et al. Mutations in rice (Oryza sativa) heavy metal ATPase 2 (OsHMA2) restrict the translocation of zinc and cadmium. Plant Cell Physiol. 2012;53(1):213-24.
Satoh-Nagasawa, N., Mori, M., Nakazawa, N., Kawamoto, T., Nagato, Y., Sakurai, K., Takahashi, H., Watanabe, A., & Akagi, H. (2012). Mutations in rice (Oryza sativa) heavy metal ATPase 2 (OsHMA2) restrict the translocation of zinc and cadmium. Plant & Cell Physiology, 53(1), 213-24. https://doi.org/10.1093/pcp/pcr166
Satoh-Nagasawa N, et al. Mutations in Rice (Oryza Sativa) Heavy Metal ATPase 2 (OsHMA2) Restrict the Translocation of Zinc and Cadmium. Plant Cell Physiol. 2012;53(1):213-24. PubMed PMID: 22123790.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Mutations in rice (Oryza sativa) heavy metal ATPase 2 (OsHMA2) restrict the translocation of zinc and cadmium. AU - Satoh-Nagasawa,Namiko, AU - Mori,Mikako, AU - Nakazawa,Nobushige, AU - Kawamoto,Tomohiko, AU - Nagato,Yasuo, AU - Sakurai,Kenji, AU - Takahashi,Hidekazu, AU - Watanabe,Akio, AU - Akagi,Hiromori, Y1 - 2011/11/28/ PY - 2011/11/30/entrez PY - 2011/11/30/pubmed PY - 2012/5/12/medline SP - 213 EP - 24 JF - Plant & cell physiology JO - Plant Cell Physiol VL - 53 IS - 1 N2 - Widespread soil contamination with heavy metals has fostered the need for plant breeders to develop new crops that do not accumulate heavy metals. Metal-transporting transmembrane proteins that transport heavy metals across the plant plasma membrane are key targets for developing these new crops. Oryza sativa heavy metal ATPase 3 (OsHMA3) is known to be a useful gene for limiting cadmium (Cd) accumulation in rice. OsHMA2 is a close homolog of OsHMA3, but the function of OsHMA2 is unknown. To gain insight into the function of OsHMA2, we analyzed three Tos17 insertion mutants. The translocation ratios of zinc (Zn) and Cd were clearly lower in all mutants than in the wild type, suggesting that OsHMA2 is a major transporter of Zn and Cd from roots to shoots. By comparing each allele in the OsHMA2 protein structure and measuring the Cd translocation ratio, we identified the C-terminal region as essential for Cd translocation into shoots. Two alleles were identified as good material for breeding rice that does not contain Cd in the grain but does contain some Zn, and that grows normally. SN - 1471-9053 UR - https://www.unboundmedicine.com/medline/citation/22123790/Mutations_in_rice__Oryza_sativa__heavy_metal_ATPase_2__OsHMA2__restrict_the_translocation_of_zinc_and_cadmium_ DB - PRIME DP - Unbound Medicine ER -