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Red blood cell aggregation in diabetes mellitus.
Int Angiol. 1990 Jan-Mar; 9(1):11-5.IA

Abstract

The aim of this work is to study the red blood cell aggregation in diabetic patients. Investigations have been performed via rheometric technics on four various types of diabetics (diabetics with good metabolic control, diabetics with poor metabolic control, diabetics with a distal angiopathy, without clinical signs, diabetics with a distal angiopathy characterized by cutaneous trophic disorders). Results, compared with those of healthy subjects, show that the reversible phenomenon of erythrocyte aggregation is significantly modified in diabetic. Indeed, the red cell aggregation tendency is found to be increased in diabetics. This hyperaggregation becomes more important when the diabetes is characterized by a poor metabolic control or a distal angiopathy with or without cutaneous trophic disorders. Disturbances of red cell aggregation observed in this report are discussed as a result of plasma protein changes and may confirm the role of hemorheological properties in the pathogenesis of diabetic angiopathy.

Authors+Show Affiliations

Unité de Recherches d'Hémorhéologie Clinique, Centre Hospitalier de Nevers, France.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

2212794

Citation

Le Devehat, C, et al. "Red Blood Cell Aggregation in Diabetes Mellitus." International Angiology : a Journal of the International Union of Angiology, vol. 9, no. 1, 1990, pp. 11-5.
Le Devehat C, Vimeux M, Bondoux G, et al. Red blood cell aggregation in diabetes mellitus. Int Angiol. 1990;9(1):11-5.
Le Devehat, C., Vimeux, M., Bondoux, G., & Khodabandehlou, T. (1990). Red blood cell aggregation in diabetes mellitus. International Angiology : a Journal of the International Union of Angiology, 9(1), 11-5.
Le Devehat C, et al. Red Blood Cell Aggregation in Diabetes Mellitus. Int Angiol. 1990;9(1):11-5. PubMed PMID: 2212794.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Red blood cell aggregation in diabetes mellitus. AU - Le Devehat,C, AU - Vimeux,M, AU - Bondoux,G, AU - Khodabandehlou,T, PY - 1990/1/1/pubmed PY - 1990/1/1/medline PY - 1990/1/1/entrez SP - 11 EP - 5 JF - International angiology : a journal of the International Union of Angiology JO - Int Angiol VL - 9 IS - 1 N2 - The aim of this work is to study the red blood cell aggregation in diabetic patients. Investigations have been performed via rheometric technics on four various types of diabetics (diabetics with good metabolic control, diabetics with poor metabolic control, diabetics with a distal angiopathy, without clinical signs, diabetics with a distal angiopathy characterized by cutaneous trophic disorders). Results, compared with those of healthy subjects, show that the reversible phenomenon of erythrocyte aggregation is significantly modified in diabetic. Indeed, the red cell aggregation tendency is found to be increased in diabetics. This hyperaggregation becomes more important when the diabetes is characterized by a poor metabolic control or a distal angiopathy with or without cutaneous trophic disorders. Disturbances of red cell aggregation observed in this report are discussed as a result of plasma protein changes and may confirm the role of hemorheological properties in the pathogenesis of diabetic angiopathy. SN - 0392-9590 UR - https://www.unboundmedicine.com/medline/citation/2212794/Red_blood_cell_aggregation_in_diabetes_mellitus_ L2 - http://www.diseaseinfosearch.org/result/2236 DB - PRIME DP - Unbound Medicine ER -