Tags

Type your tag names separated by a space and hit enter

An updated analysis of hepatitis C virus genotypes and subtypes based on the complete coding region.
Liver Int. 2012 Feb; 32(2):339-45.LI

Abstract

BACKGROUND

The hepatitis C virus (HCV) genomic database is expanding rapidly.

AIMS

There is a need to provide an updated phylogenetic tree analysis based on the complete coding region of HCV.

METHODS

All available HCV complete genome sequences in the HCV databases available through October 2010 were analyzed.

RESULTS

The assignment of all known complete sequences up-to-date confirmed the previous six major genotypes and one new sequence, which have been provisionally assigned as subtype 7a. New recombinant forms of HCV, although uncommon, have been detected and were found to have different crossover points.

CONCLUSION

This updated analysis based on the complete region of HCV confirmed the validity of the previously assigned genotypes/subtypes and provided an up-to-date reference for future basic research and clinical studies.

Authors+Show Affiliations

Department of Internal Medicine, Fujita Health University Nanakuri Sanatorium, Mie, Japan.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

22142261

Citation

Nakano, Tatsunori, et al. "An Updated Analysis of Hepatitis C Virus Genotypes and Subtypes Based On the Complete Coding Region." Liver International : Official Journal of the International Association for the Study of the Liver, vol. 32, no. 2, 2012, pp. 339-45.
Nakano T, Lau GM, Lau GM, et al. An updated analysis of hepatitis C virus genotypes and subtypes based on the complete coding region. Liver Int. 2012;32(2):339-45.
Nakano, T., Lau, G. M., Lau, G. M., Sugiyama, M., & Mizokami, M. (2012). An updated analysis of hepatitis C virus genotypes and subtypes based on the complete coding region. Liver International : Official Journal of the International Association for the Study of the Liver, 32(2), 339-45. https://doi.org/10.1111/j.1478-3231.2011.02684.x
Nakano T, et al. An Updated Analysis of Hepatitis C Virus Genotypes and Subtypes Based On the Complete Coding Region. Liver Int. 2012;32(2):339-45. PubMed PMID: 22142261.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - An updated analysis of hepatitis C virus genotypes and subtypes based on the complete coding region. AU - Nakano,Tatsunori, AU - Lau,Gillian M G, AU - Lau,Grace M L, AU - Sugiyama,Masaya, AU - Mizokami,Masashi, Y1 - 2011/12/05/ PY - 2011/08/09/received PY - 2011/10/09/accepted PY - 2011/12/7/entrez PY - 2011/12/7/pubmed PY - 2012/5/4/medline SP - 339 EP - 45 JF - Liver international : official journal of the International Association for the Study of the Liver JO - Liver Int VL - 32 IS - 2 N2 - BACKGROUND: The hepatitis C virus (HCV) genomic database is expanding rapidly. AIMS: There is a need to provide an updated phylogenetic tree analysis based on the complete coding region of HCV. METHODS: All available HCV complete genome sequences in the HCV databases available through October 2010 were analyzed. RESULTS: The assignment of all known complete sequences up-to-date confirmed the previous six major genotypes and one new sequence, which have been provisionally assigned as subtype 7a. New recombinant forms of HCV, although uncommon, have been detected and were found to have different crossover points. CONCLUSION: This updated analysis based on the complete region of HCV confirmed the validity of the previously assigned genotypes/subtypes and provided an up-to-date reference for future basic research and clinical studies. SN - 1478-3231 UR - https://www.unboundmedicine.com/medline/citation/22142261/An_updated_analysis_of_hepatitis_C_virus_genotypes_and_subtypes_based_on_the_complete_coding_region_ L2 - https://doi.org/10.1111/j.1478-3231.2011.02684.x DB - PRIME DP - Unbound Medicine ER -