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Prevalence and risk factors for primary open-angle glaucoma in a rural northeast China population: a population-based survey in Bin County, Harbin.
Eye (Lond) 2012; 26(2):283-91E

Abstract

PURPOSE

To estimate the prevalence and associated risk factors of primary open-angle glaucoma (POAG) in a rural population in northeast China.

METHODS

A population-based survey was conducted within Bin County, Harbin of northeast China. Glaucoma was diagnosed using International Society of Geographical and Epidemiological Ophthalmology criteria. All the subjects underwent a complete ophthalmic examination.

RESULTS

A total of 4956 (86.0%) of 5762 subjects aged 40 years or older were examined. The mean intraocular pressure (IOP) of right eyes was 14.0 (95% confidence interval (CI), 13.9 to 14.1) mm Hg. The prevalence of POAG was 0.71% (35/4956, 95% CI, 0.47 to 0.93). In these POAG subjects, 17 (48.6%) had elevated IOP >21 mm Hg in either eye, 3 (8.8%) participants had been treated by laser trabeculoplasty or trabeculectomy and were known to have POAG. Vision impairment to varying degrees was present in 20 subjects (58.8%) with 1 subject blind in both eyes and 8 subjects blind in one eye. On multivariate analysis, age, family history of glaucoma, systemic hypertension, and IOP were regarded as significant independent risk factors.

CONCLUSIONS

POAG is a disease of serious consequence and of low diagnosis and treatment rates in rural northeast China. Age, family history of glaucoma, systemic hypertension, and IOP remain as significant independent risk factors for POAG.

Authors+Show Affiliations

Department of Ophthalmology, The Second Affiliated Hospital, Harbin Medical University, Harbin, Heilongjiang, China.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

22157917

Citation

Sun, J, et al. "Prevalence and Risk Factors for Primary Open-angle Glaucoma in a Rural Northeast China Population: a Population-based Survey in Bin County, Harbin." Eye (London, England), vol. 26, no. 2, 2012, pp. 283-91.
Sun J, Zhou X, Kang Y, et al. Prevalence and risk factors for primary open-angle glaucoma in a rural northeast China population: a population-based survey in Bin County, Harbin. Eye (Lond). 2012;26(2):283-91.
Sun, J., Zhou, X., Kang, Y., Yan, L., Sun, X., Sui, H., ... Yuan, H. (2012). Prevalence and risk factors for primary open-angle glaucoma in a rural northeast China population: a population-based survey in Bin County, Harbin. Eye (London, England), 26(2), pp. 283-91. doi:10.1038/eye.2011.243.
Sun J, et al. Prevalence and Risk Factors for Primary Open-angle Glaucoma in a Rural Northeast China Population: a Population-based Survey in Bin County, Harbin. Eye (Lond). 2012;26(2):283-91. PubMed PMID: 22157917.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Prevalence and risk factors for primary open-angle glaucoma in a rural northeast China population: a population-based survey in Bin County, Harbin. AU - Sun,J, AU - Zhou,X, AU - Kang,Y, AU - Yan,L, AU - Sun,X, AU - Sui,H, AU - Qin,D, AU - Yuan,H, Y1 - 2011/12/09/ PY - 2011/12/14/entrez PY - 2011/12/14/pubmed PY - 2012/3/29/medline SP - 283 EP - 91 JF - Eye (London, England) JO - Eye (Lond) VL - 26 IS - 2 N2 - PURPOSE: To estimate the prevalence and associated risk factors of primary open-angle glaucoma (POAG) in a rural population in northeast China. METHODS: A population-based survey was conducted within Bin County, Harbin of northeast China. Glaucoma was diagnosed using International Society of Geographical and Epidemiological Ophthalmology criteria. All the subjects underwent a complete ophthalmic examination. RESULTS: A total of 4956 (86.0%) of 5762 subjects aged 40 years or older were examined. The mean intraocular pressure (IOP) of right eyes was 14.0 (95% confidence interval (CI), 13.9 to 14.1) mm Hg. The prevalence of POAG was 0.71% (35/4956, 95% CI, 0.47 to 0.93). In these POAG subjects, 17 (48.6%) had elevated IOP >21 mm Hg in either eye, 3 (8.8%) participants had been treated by laser trabeculoplasty or trabeculectomy and were known to have POAG. Vision impairment to varying degrees was present in 20 subjects (58.8%) with 1 subject blind in both eyes and 8 subjects blind in one eye. On multivariate analysis, age, family history of glaucoma, systemic hypertension, and IOP were regarded as significant independent risk factors. CONCLUSIONS: POAG is a disease of serious consequence and of low diagnosis and treatment rates in rural northeast China. Age, family history of glaucoma, systemic hypertension, and IOP remain as significant independent risk factors for POAG. SN - 1476-5454 UR - https://www.unboundmedicine.com/medline/citation/22157917/Prevalence_and_risk_factors_for_primary_open_angle_glaucoma_in_a_rural_northeast_China_population:_a_population_based_survey_in_Bin_County_Harbin_ L2 - http://dx.doi.org/10.1038/eye.2011.243 DB - PRIME DP - Unbound Medicine ER -