Tags

Type your tag names separated by a space and hit enter

Dietary antioxidant intake is associated with the prevalence but not incidence of age-related hearing loss.
J Nutr Health Aging 2011; 15(10):896-900JN

Abstract

OBJECTIVES

Diet is one of the few modifiable risk factors for age-related hearing loss. We aimed to examine the link between dietary and supplement intakes of antioxidants, and both the prevalence and 5-year incidence of measured hearing loss.

DESIGN

Cross-sectional and 5-year longitudinal analyses.

SETTING

Blue Mountains, Sydney, Australia.

PARTICIPANTS

2,956 Blue Mountains Hearing Study participants aged 50+ at baseline, examined during 1997-9 to 2002-4.

MEASUREMENTS

Age-related hearing loss was measured and defined as the pure-tone average of frequencies 0.5, 1.0, 2.0 and 4.0 kHz >25 dB HL. Dietary data were collected in a semi-quantitative food frequency questionnaire, and intakes of α-carotene; β-carotene; β-cryptoxanthin; lutein and zeaxanthin; lycopene; vitamins A, C and E; iron and zinc were calculated.

RESULTS

After adjusting for age, sex, smoking, education, occupational noise exposure, family history of hearing loss, history of diagnosed diabetes and stroke, each standard deviation (SD) increase in dietary vitamin E intake was associated with a 14% reduced likelihood of prevalent hearing loss, odds ratio, OR, 0.86 (95% confidence interval, CI, 0.78-0.98). Those in the highest quintile of dietary vitamin A intake had a 47% reduced risk of having moderate or greater hearing loss (>40 dB HL) compared to those in the lowest quintile of intake, multivariable-adjusted OR 0.53 (CI 0.30-0.92), P for trend = 0.04. However, dietary antioxidant intake was not associated with the 5-year incidence of hearing loss.

CONCLUSIONS

Dietary vitamin A and vitamin E intake were significantly associated with the prevalence of hearing loss. However, dietary antioxidant intake did not increase the risk of incident hearing loss. Further large, prospective studies are warranted to assess these relationships in older adults.

Authors+Show Affiliations

Centre for Vision Research, Department of Ophthalmology, University of Sydney, NSW, Australia.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

22159779

Citation

Gopinath, B, et al. "Dietary Antioxidant Intake Is Associated With the Prevalence but Not Incidence of Age-related Hearing Loss." The Journal of Nutrition, Health & Aging, vol. 15, no. 10, 2011, pp. 896-900.
Gopinath B, Flood VM, McMahon CM, et al. Dietary antioxidant intake is associated with the prevalence but not incidence of age-related hearing loss. J Nutr Health Aging. 2011;15(10):896-900.
Gopinath, B., Flood, V. M., McMahon, C. M., Burlutsky, G., Spankovich, C., Hood, L. J., & Mitchell, P. (2011). Dietary antioxidant intake is associated with the prevalence but not incidence of age-related hearing loss. The Journal of Nutrition, Health & Aging, 15(10), pp. 896-900.
Gopinath B, et al. Dietary Antioxidant Intake Is Associated With the Prevalence but Not Incidence of Age-related Hearing Loss. J Nutr Health Aging. 2011;15(10):896-900. PubMed PMID: 22159779.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Dietary antioxidant intake is associated with the prevalence but not incidence of age-related hearing loss. AU - Gopinath,B, AU - Flood,V M, AU - McMahon,C M, AU - Burlutsky,G, AU - Spankovich,C, AU - Hood,L J, AU - Mitchell,P, PY - 2011/12/14/entrez PY - 2011/12/14/pubmed PY - 2012/6/6/medline SP - 896 EP - 900 JF - The journal of nutrition, health & aging JO - J Nutr Health Aging VL - 15 IS - 10 N2 - OBJECTIVES: Diet is one of the few modifiable risk factors for age-related hearing loss. We aimed to examine the link between dietary and supplement intakes of antioxidants, and both the prevalence and 5-year incidence of measured hearing loss. DESIGN: Cross-sectional and 5-year longitudinal analyses. SETTING: Blue Mountains, Sydney, Australia. PARTICIPANTS: 2,956 Blue Mountains Hearing Study participants aged 50+ at baseline, examined during 1997-9 to 2002-4. MEASUREMENTS: Age-related hearing loss was measured and defined as the pure-tone average of frequencies 0.5, 1.0, 2.0 and 4.0 kHz >25 dB HL. Dietary data were collected in a semi-quantitative food frequency questionnaire, and intakes of α-carotene; β-carotene; β-cryptoxanthin; lutein and zeaxanthin; lycopene; vitamins A, C and E; iron and zinc were calculated. RESULTS: After adjusting for age, sex, smoking, education, occupational noise exposure, family history of hearing loss, history of diagnosed diabetes and stroke, each standard deviation (SD) increase in dietary vitamin E intake was associated with a 14% reduced likelihood of prevalent hearing loss, odds ratio, OR, 0.86 (95% confidence interval, CI, 0.78-0.98). Those in the highest quintile of dietary vitamin A intake had a 47% reduced risk of having moderate or greater hearing loss (>40 dB HL) compared to those in the lowest quintile of intake, multivariable-adjusted OR 0.53 (CI 0.30-0.92), P for trend = 0.04. However, dietary antioxidant intake was not associated with the 5-year incidence of hearing loss. CONCLUSIONS: Dietary vitamin A and vitamin E intake were significantly associated with the prevalence of hearing loss. However, dietary antioxidant intake did not increase the risk of incident hearing loss. Further large, prospective studies are warranted to assess these relationships in older adults. SN - 1760-4788 UR - https://www.unboundmedicine.com/medline/citation/22159779/Dietary_antioxidant_intake_is_associated_with_the_prevalence_but_not_incidence_of_age_related_hearing_loss_ L2 - https://medlineplus.gov/vitamina.html DB - PRIME DP - Unbound Medicine ER -