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Chemical composition and anticandidal properties of the essential oil isolated from aerial parts of Cotula cinerea: a rare and threatened medicinal plant in Morocco.
Nat Prod Commun. 2011 Oct; 6(10):1491-4.NP

Abstract

The chemical composition and anticandidal properties of the essential oil of Moroccan Cotula cinerea aerial parts have been examined. GC-MS data were used to identify 24 constituents. Oxygenated monoterpenes constituted the main fraction with trans-thujone (41.4%), cis-verbenyl acetate (24.7%), 1,8-cineole (8.2%) and camphor (5.5%) as the major components. The anticandidal activity of the essential oil was evaluated using a panel of human pathogenic fungi (Candida albicans CCMM L4 and CCMM L5, C. krusei CCMM L10, C. glabrata CCMM L7 and C. parapsilosis CCMM L18). The oil showed high anticandidal activity against all investigated strains with minimal inhibitory concentrations of 3.2 to 4.7 mg/mL depending on the tested yeast and 5.9 mg/mL as a minimal candidicidal concentration value. These findings add significant information to the pharmacological activity of Cotula cinerea essential oil, which may present a good alternative to antibiotics for the treatment of resistant strains of Candida.

Authors+Show Affiliations

Laboratoire de Biotechnologies, Protections et Valorisation des Ressources Végétale, Faculté des Sciences, Semlalia, Université Cadi Ayyad, Marrakech, Morocco.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

22164791

Citation

El Bouzidi, Leila, et al. "Chemical Composition and Anticandidal Properties of the Essential Oil Isolated From Aerial Parts of Cotula Cinerea: a Rare and Threatened Medicinal Plant in Morocco." Natural Product Communications, vol. 6, no. 10, 2011, pp. 1491-4.
El Bouzidi L, Abbad A, Fattarsi K, et al. Chemical composition and anticandidal properties of the essential oil isolated from aerial parts of Cotula cinerea: a rare and threatened medicinal plant in Morocco. Nat Prod Commun. 2011;6(10):1491-4.
El Bouzidi, L., Abbad, A., Fattarsi, K., Hassani, L., Leach, D., Markouk, M., Legendre, L., & Bekkouche, K. (2011). Chemical composition and anticandidal properties of the essential oil isolated from aerial parts of Cotula cinerea: a rare and threatened medicinal plant in Morocco. Natural Product Communications, 6(10), 1491-4.
El Bouzidi L, et al. Chemical Composition and Anticandidal Properties of the Essential Oil Isolated From Aerial Parts of Cotula Cinerea: a Rare and Threatened Medicinal Plant in Morocco. Nat Prod Commun. 2011;6(10):1491-4. PubMed PMID: 22164791.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Chemical composition and anticandidal properties of the essential oil isolated from aerial parts of Cotula cinerea: a rare and threatened medicinal plant in Morocco. AU - El Bouzidi,Leila, AU - Abbad,Abdelaziz, AU - Fattarsi,Karine, AU - Hassani,Lahcen, AU - Leach,David, AU - Markouk,Mohammed, AU - Legendre,Laurent, AU - Bekkouche,Khalid, PY - 2011/12/15/entrez PY - 2011/12/15/pubmed PY - 2012/3/1/medline SP - 1491 EP - 4 JF - Natural product communications JO - Nat Prod Commun VL - 6 IS - 10 N2 - The chemical composition and anticandidal properties of the essential oil of Moroccan Cotula cinerea aerial parts have been examined. GC-MS data were used to identify 24 constituents. Oxygenated monoterpenes constituted the main fraction with trans-thujone (41.4%), cis-verbenyl acetate (24.7%), 1,8-cineole (8.2%) and camphor (5.5%) as the major components. The anticandidal activity of the essential oil was evaluated using a panel of human pathogenic fungi (Candida albicans CCMM L4 and CCMM L5, C. krusei CCMM L10, C. glabrata CCMM L7 and C. parapsilosis CCMM L18). The oil showed high anticandidal activity against all investigated strains with minimal inhibitory concentrations of 3.2 to 4.7 mg/mL depending on the tested yeast and 5.9 mg/mL as a minimal candidicidal concentration value. These findings add significant information to the pharmacological activity of Cotula cinerea essential oil, which may present a good alternative to antibiotics for the treatment of resistant strains of Candida. SN - 1934-578X UR - https://www.unboundmedicine.com/medline/citation/22164791/Chemical_composition_and_anticandidal_properties_of_the_essential_oil_isolated_from_aerial_parts_of_Cotula_cinerea:_a_rare_and_threatened_medicinal_plant_in_Morocco_ DB - PRIME DP - Unbound Medicine ER -