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Pulmonary coccidioidomycosis.
Semin Respir Crit Care Med. 2011 Dec; 32(6):754-63.SR

Abstract

Coccidioidomycosis refers to the spectrum of disease caused by the dimorphic fungi Coccidioides immitis and Coccidioides posadasii. Clinical manifestations vary depending upon both the extent of infection and the immune status of the host. Coccidioidomycosis has been reported to involve almost all organ systems; however, pulmonary disease is the most common clinical manifestation. The incidence of coccidioidomycosis continues to rise, and primary coccidioidal pneumonia accounts for 17 to 29% of all cases of community-acquired pneumonia in endemic regions. The majority of patients with coccidioidomycosis resolve their initial infection without sequelae; however, several patients develop complications of disease ranging in severity from complicated pulmonary coccidioidomycosis to widely disseminated disease with immediately life-threatening manifestations. This review focuses on complications of pulmonary coccidioidomycosis with an emphasis on the management of primary coccidioidal infection, solitary pulmonary nodules, pleural effusions, cavitary disease, acute respiratory distress syndrome (ARDS), miliary disease, and sepsis.

Authors+Show Affiliations

Department of Internal Medicine, Division of Infectious Diseases, University of California-Davis, Davis, California 95616, USA. grthompson@ucdavis.edu

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

22167403

Citation

Thompson, George R.. "Pulmonary Coccidioidomycosis." Seminars in Respiratory and Critical Care Medicine, vol. 32, no. 6, 2011, pp. 754-63.
Thompson GR. Pulmonary coccidioidomycosis. Semin Respir Crit Care Med. 2011;32(6):754-63.
Thompson, G. R. (2011). Pulmonary coccidioidomycosis. Seminars in Respiratory and Critical Care Medicine, 32(6), 754-63. https://doi.org/10.1055/s-0031-1295723
Thompson GR. Pulmonary Coccidioidomycosis. Semin Respir Crit Care Med. 2011;32(6):754-63. PubMed PMID: 22167403.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Pulmonary coccidioidomycosis. A1 - Thompson,George R,3rd Y1 - 2011/12/13/ PY - 2011/12/15/entrez PY - 2011/12/15/pubmed PY - 2012/4/4/medline SP - 754 EP - 63 JF - Seminars in respiratory and critical care medicine JO - Semin Respir Crit Care Med VL - 32 IS - 6 N2 - Coccidioidomycosis refers to the spectrum of disease caused by the dimorphic fungi Coccidioides immitis and Coccidioides posadasii. Clinical manifestations vary depending upon both the extent of infection and the immune status of the host. Coccidioidomycosis has been reported to involve almost all organ systems; however, pulmonary disease is the most common clinical manifestation. The incidence of coccidioidomycosis continues to rise, and primary coccidioidal pneumonia accounts for 17 to 29% of all cases of community-acquired pneumonia in endemic regions. The majority of patients with coccidioidomycosis resolve their initial infection without sequelae; however, several patients develop complications of disease ranging in severity from complicated pulmonary coccidioidomycosis to widely disseminated disease with immediately life-threatening manifestations. This review focuses on complications of pulmonary coccidioidomycosis with an emphasis on the management of primary coccidioidal infection, solitary pulmonary nodules, pleural effusions, cavitary disease, acute respiratory distress syndrome (ARDS), miliary disease, and sepsis. SN - 1098-9048 UR - https://www.unboundmedicine.com/medline/citation/22167403/full_citation L2 - http://www.thieme-connect.com/DOI/DOI?10.1055/s-0031-1295723 DB - PRIME DP - Unbound Medicine ER -