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Preoperative erectile function represents a significant predictor of postoperative urinary continence recovery in patients treated with bilateral nerve sparing radical prostatectomy.
J Urol. 2012 Feb; 187(2):569-74.JU

Abstract

PURPOSE

The association between baseline functional status and urinary continence recovery after radical prostatectomy remains controversial. We tested the hypothesis that baseline erectile and urinary function predicts urinary continence recovery after bilateral nerve sparing radical prostatectomy.

MATERIALS AND METHODS

The study included 752 patients with prostate cancer treated with bilateral nerve sparing radical prostatectomy between 2003 and 2009. All patients had preoperative functional and oncological data available, including age at surgery, body mass index, prostate specific antigen, and erectile and urinary function. Preoperatively erectile and urinary function was assessed by the erectile function domain of the International Index of Erectile Function and the International Prostatic Symptoms Score. Urinary continence was defined as wearing no pads. Univariate and multivariate Cox regression models were used to test the association between predictors and urinary continence recovery after surgery.

RESULTS

At a mean postoperative followup of 30.7 months (median 29, range 1 to 80) 611 patients (81.3%) had recovered urinary continence. Overall the urinary continence recovery rate at 1 and 3 years was 73.9% and 82.2%, respectively. On univariate Cox regression analysis patient age and the preoperative score on the erectile function domain of the International Index of Erectile Function were significantly associated with urinary continence recovery (each p ≤ 0.04). On multivariate analysis age at surgery and the preoperative erectile function domain of the International Index of Erectile Function were the only independent predictors of urinary continence recovery after bilateral nerve sparing radical prostatectomy (each p ≤ 0.04).

CONCLUSIONS

Age and preoperative erectile function should be considered for urinary continence predictions after bilateral nerve sparing radical prostatectomy and for accurate patient counseling before surgery. Preoperative erectile function might be a marker of pelvic vascular disease, which may affect the status of the external urinary sphincter.

Authors+Show Affiliations

Department of Urology, University Vita-Salute San Raffaele, Milan, Italy. giorgan10@libero.itNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

22177170

Citation

Gandaglia, Giorgio, et al. "Preoperative Erectile Function Represents a Significant Predictor of Postoperative Urinary Continence Recovery in Patients Treated With Bilateral Nerve Sparing Radical Prostatectomy." The Journal of Urology, vol. 187, no. 2, 2012, pp. 569-74.
Gandaglia G, Suardi N, Gallina A, et al. Preoperative erectile function represents a significant predictor of postoperative urinary continence recovery in patients treated with bilateral nerve sparing radical prostatectomy. J Urol. 2012;187(2):569-74.
Gandaglia, G., Suardi, N., Gallina, A., Capitanio, U., Abdollah, F., Salonia, A., Nava, L., Colombo, R., Guazzoni, G., Rigatti, P., Montorsi, F., & Briganti, A. (2012). Preoperative erectile function represents a significant predictor of postoperative urinary continence recovery in patients treated with bilateral nerve sparing radical prostatectomy. The Journal of Urology, 187(2), 569-74. https://doi.org/10.1016/j.juro.2011.10.034
Gandaglia G, et al. Preoperative Erectile Function Represents a Significant Predictor of Postoperative Urinary Continence Recovery in Patients Treated With Bilateral Nerve Sparing Radical Prostatectomy. J Urol. 2012;187(2):569-74. PubMed PMID: 22177170.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Preoperative erectile function represents a significant predictor of postoperative urinary continence recovery in patients treated with bilateral nerve sparing radical prostatectomy. AU - Gandaglia,Giorgio, AU - Suardi,Nazareno, AU - Gallina,Andrea, AU - Capitanio,Umberto, AU - Abdollah,Firas, AU - Salonia,Andrea, AU - Nava,Luciano, AU - Colombo,Renzo, AU - Guazzoni,Giorgio, AU - Rigatti,Patrizio, AU - Montorsi,Francesco, AU - Briganti,Alberto, Y1 - 2011/12/15/ PY - 2011/06/09/received PY - 2011/12/20/entrez PY - 2011/12/20/pubmed PY - 2012/3/7/medline SP - 569 EP - 74 JF - The Journal of urology JO - J Urol VL - 187 IS - 2 N2 - PURPOSE: The association between baseline functional status and urinary continence recovery after radical prostatectomy remains controversial. We tested the hypothesis that baseline erectile and urinary function predicts urinary continence recovery after bilateral nerve sparing radical prostatectomy. MATERIALS AND METHODS: The study included 752 patients with prostate cancer treated with bilateral nerve sparing radical prostatectomy between 2003 and 2009. All patients had preoperative functional and oncological data available, including age at surgery, body mass index, prostate specific antigen, and erectile and urinary function. Preoperatively erectile and urinary function was assessed by the erectile function domain of the International Index of Erectile Function and the International Prostatic Symptoms Score. Urinary continence was defined as wearing no pads. Univariate and multivariate Cox regression models were used to test the association between predictors and urinary continence recovery after surgery. RESULTS: At a mean postoperative followup of 30.7 months (median 29, range 1 to 80) 611 patients (81.3%) had recovered urinary continence. Overall the urinary continence recovery rate at 1 and 3 years was 73.9% and 82.2%, respectively. On univariate Cox regression analysis patient age and the preoperative score on the erectile function domain of the International Index of Erectile Function were significantly associated with urinary continence recovery (each p ≤ 0.04). On multivariate analysis age at surgery and the preoperative erectile function domain of the International Index of Erectile Function were the only independent predictors of urinary continence recovery after bilateral nerve sparing radical prostatectomy (each p ≤ 0.04). CONCLUSIONS: Age and preoperative erectile function should be considered for urinary continence predictions after bilateral nerve sparing radical prostatectomy and for accurate patient counseling before surgery. Preoperative erectile function might be a marker of pelvic vascular disease, which may affect the status of the external urinary sphincter. SN - 1527-3792 UR - https://www.unboundmedicine.com/medline/citation/22177170/Preoperative_erectile_function_represents_a_significant_predictor_of_postoperative_urinary_continence_recovery_in_patients_treated_with_bilateral_nerve_sparing_radical_prostatectomy_ L2 - https://www.jurology.com/doi/10.1016/j.juro.2011.10.034?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -