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[Pulmonary cryptococcosis: analysis of 38 cases].
Zhonghua Jie He He Hu Xi Za Zhi. 2011 Sep; 34(9):653-6.ZJ

Abstract

OBJECTIVE

To investigate the clinical features, radiology, diagnosis and treatment of pulmonary cryptococcosis.

METHODS

A total of 38 cases of pulmonary cryptococcosis, confirmed by pathological examinations at Fuzhou General Clinical Medical College, Fujian Medical University from March 2003 to February 2010, were retrospectively studied.

RESULTS

All of the cases were community-acquired. The patients consisted of 29 males and 9 females, aged from 21 to 70 years. There were no underlying diseases in 29 cases. The CD(4) cell numbers were normal in 20 patients. Radiological study showed that the majority of the lesions (35 cases) were close to the pleura. Lower lungs were often involved (left 21 and right 23). Pulmonary nodules, either solitary nodules (11 cases) or multiple nodules (16 cases), were the most common CT finding. The lesions had a higher standardized uptake value (SUV) in 4 patients with a PET-CT scan. The lung specimens of 33 cases were obtained by CT guided transthoracic needle aspiration biopsy. The disease was cured in 34 cases, and improved in 3 cases, but 1 died.

CONCLUSIONS

Pulmonary cryptococcosis must be considered in the differential diagnosis of lesions of the lungs. The disease has some characteristics on radiology, such as multiple lesions, always close to the pleura and occurs frequently in the lower lungs. CT guided percutaneous biopsy is a safe and effective method for diagnosis.

Links

Publisher Full Text

Authors+Show Affiliations

Xu LY
Divison of Pulmonary & Critical Care Medicine, Fuzhou General Hospital of Nanjing Military Command, Fuzhou 350025, China.
Liu DL
No affiliation info available
Yu YH
No affiliation info available
Wang TZ
No affiliation info available
Liu DM
No affiliation info available
Lai GX
No affiliation info available

MeSH

AdultAgedCryptococcosisCryptococcusFemaleHumansLungLung Diseases, FungalMaleMiddle AgedRetrospective StudiesYoung Adult

Pub Type(s)

English Abstract
Journal Article

Language

chi

PubMed ID

22177488

Citation

Xu, Li-yu, et al. "[Pulmonary Cryptococcosis: Analysis of 38 Cases]." Zhonghua Jie He He Hu Xi Za Zhi = Zhonghua Jiehe He Huxi Zazhi = Chinese Journal of Tuberculosis and Respiratory Diseases, vol. 34, no. 9, 2011, pp. 653-6.
Xu LY, Liu DL, Yu YH, et al. [Pulmonary cryptococcosis: analysis of 38 cases]. Zhonghua Jie He He Hu Xi Za Zhi. 2011;34(9):653-6.
Xu, L. Y., Liu, D. L., Yu, Y. H., Wang, T. Z., Liu, D. M., & Lai, G. X. (2011). [Pulmonary cryptococcosis: analysis of 38 cases]. Zhonghua Jie He He Hu Xi Za Zhi = Zhonghua Jiehe He Huxi Zazhi = Chinese Journal of Tuberculosis and Respiratory Diseases, 34(9), 653-6.
Xu LY, et al. [Pulmonary Cryptococcosis: Analysis of 38 Cases]. Zhonghua Jie He He Hu Xi Za Zhi. 2011;34(9):653-6. PubMed PMID: 22177488.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Pulmonary cryptococcosis: analysis of 38 cases]. AU - Xu,Li-yu, AU - Liu,De-ling, AU - Yu,Ying-hao, AU - Wang,Tie-zhu, AU - Liu,Dao-ming, AU - Lai,Guo-xiang, PY - 2011/12/20/entrez PY - 2011/12/20/pubmed PY - 2012/10/23/medline SP - 653 EP - 6 JF - Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases JO - Zhonghua Jie He He Hu Xi Za Zhi VL - 34 IS - 9 N2 - OBJECTIVE: To investigate the clinical features, radiology, diagnosis and treatment of pulmonary cryptococcosis. METHODS: A total of 38 cases of pulmonary cryptococcosis, confirmed by pathological examinations at Fuzhou General Clinical Medical College, Fujian Medical University from March 2003 to February 2010, were retrospectively studied. RESULTS: All of the cases were community-acquired. The patients consisted of 29 males and 9 females, aged from 21 to 70 years. There were no underlying diseases in 29 cases. The CD(4) cell numbers were normal in 20 patients. Radiological study showed that the majority of the lesions (35 cases) were close to the pleura. Lower lungs were often involved (left 21 and right 23). Pulmonary nodules, either solitary nodules (11 cases) or multiple nodules (16 cases), were the most common CT finding. The lesions had a higher standardized uptake value (SUV) in 4 patients with a PET-CT scan. The lung specimens of 33 cases were obtained by CT guided transthoracic needle aspiration biopsy. The disease was cured in 34 cases, and improved in 3 cases, but 1 died. CONCLUSIONS: Pulmonary cryptococcosis must be considered in the differential diagnosis of lesions of the lungs. The disease has some characteristics on radiology, such as multiple lesions, always close to the pleura and occurs frequently in the lower lungs. CT guided percutaneous biopsy is a safe and effective method for diagnosis. SN - 1001-0939 UR - https://www.unboundmedicine.com/medline/citation/22177488/[Pulmonary_cryptococcosis:_analysis_of_38_cases]_ L2 - http://journal.yiigle.com/LinkIn.do?linkin_type=pubmed&issn=1001-0939&year=2011&vol=34&issue=9&fpage=653 DB - PRIME DP - Unbound Medicine ER -