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Methicillin-resistant Staphylococcus aureus colonization in otitis-prone children.
OBJECTIVESTo examine the prevalence of methicillin-resistant Staphylococcus aureus (MRSA) colonization among children undergoing bilateral myringotomy and tube insertion with or without adenoidectomy for chronic otitis media with effusion or recurrent acute otitis media, as well as to examine the occurrence of postoperative otorrhea in children who have vs do not have MRSA colonization.
DESIGNProspective cohort study.
SETTINGHospital-based pediatric otolaryngology practice in a metropolitan area.
PATIENTSSeventy-six children (51 boys and 25 girls), with a mean (SD) age of 3.6 (1.8) years.
INTERVENTIONSCultures for S aureus from the nasopharynx, external auditory canals, middle ears, and adenoid were obtained at the time of surgery, as well as middle ear cultures for bacteriologic culture and sensitivity. Patients were followed up for the development of otorrhea.
MAIN OUTCOME MEASURESPrevalence of MRSA colonization and predictors of subsequent otorrhea.
RESULTSThe prevalence of S aureus colonization at the time of bilateral myringotomy and tube insertion was 7.9% (95% CI, 3.0%-16.4%), and the prevalence of MRSA colonization was 3.9% (95% CI, 0.8%-11.1%). All MRSA-positive specimens were resistant to erythromycin, and 2 were resistant to clindamycin. The mean (SD) follow-up period was 11.6 (3.6) months. Twenty-seven patients (35.5% [95% CI, 25.1%-46.9%]) developed at least 1 episode of otorrhea. One of 3 patients with MRSA colonization had subsequent otorrhea. The only predictor of otorrhea was younger age.
CONCLUSIONSThe prevalence of MRSA colonization among otitis-prone children was similar to rates reported among the general pediatric community. Methicillin-resistant S aureus colonization at the time of bilateral myringotomy and tube insertion was not predictive of subsequent otorrhea.
Division of Pediatric Otolaryngology, State University of New York Downstate Medical Center, 450 Clarkson Avenue, Brooklyn, NY 11203, USA., , , ,
Archives of otolaryngology--head & neck surgery 137:12 2011 Dec pg 1217-22
Methicillin-Resistant Staphylococcus aureus
Microbial Sensitivity Tests
Middle Ear Ventilation
New York City
Otitis Media with Effusion
Otitis Media, Suppurative
Pub Type(s)Journal Article
Research Support, Non-U.S. Gov't