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[Elental prevented and reduced oral mucositis during chemotherapy in patients esophageal cancer].
Gan To Kagaku Ryoho. 2011 Dec; 38(13):2597-601.GT

Abstract

Stomatitis is a side effect caused frequently by chemotherapy in patients with esophageal cancer, but a standard treatment for it has not been established. Reactive oxygen species are known to be among the causes of stomatitis induced by chemotherapy or radiotherapy, and some reports suggest that their influences might be reduced by the oral supplementation of glutamine. Elental® is one of the widely-used nutritional supplements, and its pack contains 1, 932 mg of L-glutamine (an especially high amount.). Therefore, we examined the preventive or reducing effects Elental® mey have on oral mucositis. Fifteen patients with esophageal cancer received chemotherapy, six of whom had grade one oral mucositis. All of those six patients entered the investigation, and seven courses of Elental® were administered. After seven courses, all six patients oral mucositis declined from grade 1 to grade 0. This result suggests that Elental® has preventive or reducing effects on oral mucositis.

Authors+Show Affiliations

Dept. of Clinical Oncology, Yamagata University.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article

Language

jpn

PubMed ID

22189225

Citation

Fukui, Tadahisa, et al. "[Elental Prevented and Reduced Oral Mucositis During Chemotherapy in Patients Esophageal Cancer]." Gan to Kagaku Ryoho. Cancer & Chemotherapy, vol. 38, no. 13, 2011, pp. 2597-601.
Fukui T, Itoh Y, Orihara M, et al. [Elental prevented and reduced oral mucositis during chemotherapy in patients esophageal cancer]. Gan To Kagaku Ryoho. 2011;38(13):2597-601.
Fukui, T., Itoh, Y., Orihara, M., Yoshizawa, K., Takeda, H., Kawada, S., & Yoshioka, T. (2011). [Elental prevented and reduced oral mucositis during chemotherapy in patients esophageal cancer]. Gan to Kagaku Ryoho. Cancer & Chemotherapy, 38(13), 2597-601.
Fukui T, et al. [Elental Prevented and Reduced Oral Mucositis During Chemotherapy in Patients Esophageal Cancer]. Gan To Kagaku Ryoho. 2011;38(13):2597-601. PubMed PMID: 22189225.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Elental prevented and reduced oral mucositis during chemotherapy in patients esophageal cancer]. AU - Fukui,Tadahisa, AU - Itoh,Yuriko, AU - Orihara,Mika, AU - Yoshizawa,Kazuya, AU - Takeda,Hiroaki, AU - Kawada,Sumio, AU - Yoshioka,Takashi, PY - 2011/12/23/entrez PY - 2011/12/23/pubmed PY - 2012/2/24/medline SP - 2597 EP - 601 JF - Gan to kagaku ryoho. Cancer & chemotherapy JO - Gan To Kagaku Ryoho VL - 38 IS - 13 N2 - Stomatitis is a side effect caused frequently by chemotherapy in patients with esophageal cancer, but a standard treatment for it has not been established. Reactive oxygen species are known to be among the causes of stomatitis induced by chemotherapy or radiotherapy, and some reports suggest that their influences might be reduced by the oral supplementation of glutamine. Elental® is one of the widely-used nutritional supplements, and its pack contains 1, 932 mg of L-glutamine (an especially high amount.). Therefore, we examined the preventive or reducing effects Elental® mey have on oral mucositis. Fifteen patients with esophageal cancer received chemotherapy, six of whom had grade one oral mucositis. All of those six patients entered the investigation, and seven courses of Elental® were administered. After seven courses, all six patients oral mucositis declined from grade 1 to grade 0. This result suggests that Elental® has preventive or reducing effects on oral mucositis. SN - 0385-0684 UR - https://www.unboundmedicine.com/medline/citation/22189225/[Elental_prevented_and_reduced_oral_mucositis_during_chemotherapy_in_patients_esophageal_cancer]_ L2 - http://www.pieronline.jp/openurl?issn=0385-0684&volume=38&issue=13&spage=2597 DB - PRIME DP - Unbound Medicine ER -