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Efficacy of a baiting system for vaccinating foxes against rabies with vaccinia-rabies recombinant virus.
Vet Rec. 1990 Aug 18; 127(7):165-7.VR

Abstract

The efficacy of a vaccinia-rabies recombinant virus (10(8) TCID50) contained in a machine-made baiting system has been tested in 22 captive young foxes which were divided into three experimental groups of six and a control group of four foxes. Each fox in groups 1, 2 and 3 were fed one, two and three vaccine-baits, respectively, on successive days. The four unvaccinated foxes were housed separately. As shown by the incorporation of a tetracycline biomarker into their bones, all the baited foxes ingested at least one bait. Thirty days after baiting seroconversion to rabies was observed in 15 (83 per cent) of the foxes and seroconversion to vaccinia in 14 (78 per cent). Sixteen of the 18 (89 per cent) baited foxes resisted a rabies challenge 30 days after baiting. One cub was protected against rabies despite the absence of detectable anti-rabies antibody. The results demonstrate that the bait-sachet system permits a good release of the virus suspension into the mouth.

Authors+Show Affiliations

Department of Virology and Immunology, Faculty of Veterinary Medicine, University of Liège, Brussels, Belgium.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

2219648

Citation

Brochier, B M., et al. "Efficacy of a Baiting System for Vaccinating Foxes Against Rabies With Vaccinia-rabies Recombinant Virus." The Veterinary Record, vol. 127, no. 7, 1990, pp. 165-7.
Brochier BM, Languet B, Artois M, et al. Efficacy of a baiting system for vaccinating foxes against rabies with vaccinia-rabies recombinant virus. Vet Rec. 1990;127(7):165-7.
Brochier, B. M., Languet, B., Artois, M., Zanker, S., Guittre, C., Blancou, J., Chappuis, G., Desmettre, P., & Pastoret, P. P. (1990). Efficacy of a baiting system for vaccinating foxes against rabies with vaccinia-rabies recombinant virus. The Veterinary Record, 127(7), 165-7.
Brochier BM, et al. Efficacy of a Baiting System for Vaccinating Foxes Against Rabies With Vaccinia-rabies Recombinant Virus. Vet Rec. 1990 Aug 18;127(7):165-7. PubMed PMID: 2219648.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Efficacy of a baiting system for vaccinating foxes against rabies with vaccinia-rabies recombinant virus. AU - Brochier,B M, AU - Languet,B, AU - Artois,M, AU - Zanker,S, AU - Guittre,C, AU - Blancou,J, AU - Chappuis,G, AU - Desmettre,P, AU - Pastoret,P P, PY - 1990/8/18/pubmed PY - 1990/8/18/medline PY - 1990/8/18/entrez SP - 165 EP - 7 JF - The Veterinary record JO - Vet Rec VL - 127 IS - 7 N2 - The efficacy of a vaccinia-rabies recombinant virus (10(8) TCID50) contained in a machine-made baiting system has been tested in 22 captive young foxes which were divided into three experimental groups of six and a control group of four foxes. Each fox in groups 1, 2 and 3 were fed one, two and three vaccine-baits, respectively, on successive days. The four unvaccinated foxes were housed separately. As shown by the incorporation of a tetracycline biomarker into their bones, all the baited foxes ingested at least one bait. Thirty days after baiting seroconversion to rabies was observed in 15 (83 per cent) of the foxes and seroconversion to vaccinia in 14 (78 per cent). Sixteen of the 18 (89 per cent) baited foxes resisted a rabies challenge 30 days after baiting. One cub was protected against rabies despite the absence of detectable anti-rabies antibody. The results demonstrate that the bait-sachet system permits a good release of the virus suspension into the mouth. SN - 0042-4900 UR - https://www.unboundmedicine.com/medline/citation/2219648/Efficacy_of_a_baiting_system_for_vaccinating_foxes_against_rabies_with_vaccinia_rabies_recombinant_virus_ L2 - https://medlineplus.gov/rabies.html DB - PRIME DP - Unbound Medicine ER -