Tags

Type your tag names separated by a space and hit enter

A case of malignant migrating partial seizures in infancy as a continuum of infantile epileptic encephalopathy.
Brain Dev. 2012 Oct; 34(9):768-72.BD

Abstract

The syndrome of malignant migrating partial seizures in infancy (MMPSI) is characterized by onset before the age of 6 months, nearly continuous electrographic seizures involving multiple independent areas of onset in both hemispheres, and poor developmental outcome. This report presents a case involving a patient with MMPSI, who later developed West syndrome. At the age of 2 months old, he showed multifocal partial seizures, which were refractory to antiepileptic drugs. His electroencephalogram (EEG) revealed characteristic migrating multifocal epileptiform activities and neuroimaging finding was normal. The focal seizures were refractory to antiepileptic drugs and ketogenic diet. When he was 9 months old, epilepic spasms were observed with hypsarrhythmia on EEG. He also showed severe developmental delay. MMPSI may be a continuum of infantile epileptic encephalpathy and could evolve to West syndrome.

Authors+Show Affiliations

Department of Pediatrics, College of Medicine, Kyung Hee University, Seoul, Republic of Korea.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

22197566

Citation

Lee, Eun Hye, et al. "A Case of Malignant Migrating Partial Seizures in Infancy as a Continuum of Infantile Epileptic Encephalopathy." Brain & Development, vol. 34, no. 9, 2012, pp. 768-72.
Lee EH, Yum MS, Jeong MH, et al. A case of malignant migrating partial seizures in infancy as a continuum of infantile epileptic encephalopathy. Brain Dev. 2012;34(9):768-72.
Lee, E. H., Yum, M. S., Jeong, M. H., Lee, K. Y., & Ko, T. S. (2012). A case of malignant migrating partial seizures in infancy as a continuum of infantile epileptic encephalopathy. Brain & Development, 34(9), 768-72. https://doi.org/10.1016/j.braindev.2011.11.011
Lee EH, et al. A Case of Malignant Migrating Partial Seizures in Infancy as a Continuum of Infantile Epileptic Encephalopathy. Brain Dev. 2012;34(9):768-72. PubMed PMID: 22197566.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A case of malignant migrating partial seizures in infancy as a continuum of infantile epileptic encephalopathy. AU - Lee,Eun Hye, AU - Yum,Mi-Sun, AU - Jeong,Min-Hee, AU - Lee,Kyung Yeon, AU - Ko,Tae-Sung, Y1 - 2011/12/24/ PY - 2011/08/26/received PY - 2011/11/28/revised PY - 2011/11/28/accepted PY - 2011/12/27/entrez PY - 2011/12/27/pubmed PY - 2013/1/29/medline SP - 768 EP - 72 JF - Brain & development JO - Brain Dev VL - 34 IS - 9 N2 - The syndrome of malignant migrating partial seizures in infancy (MMPSI) is characterized by onset before the age of 6 months, nearly continuous electrographic seizures involving multiple independent areas of onset in both hemispheres, and poor developmental outcome. This report presents a case involving a patient with MMPSI, who later developed West syndrome. At the age of 2 months old, he showed multifocal partial seizures, which were refractory to antiepileptic drugs. His electroencephalogram (EEG) revealed characteristic migrating multifocal epileptiform activities and neuroimaging finding was normal. The focal seizures were refractory to antiepileptic drugs and ketogenic diet. When he was 9 months old, epilepic spasms were observed with hypsarrhythmia on EEG. He also showed severe developmental delay. MMPSI may be a continuum of infantile epileptic encephalpathy and could evolve to West syndrome. SN - 1872-7131 UR - https://www.unboundmedicine.com/medline/citation/22197566/A_case_of_malignant_migrating_partial_seizures_in_infancy_as_a_continuum_of_infantile_epileptic_encephalopathy_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0387-7604(11)00336-6 DB - PRIME DP - Unbound Medicine ER -