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HIV stigma and depressive symptoms are related to adherence and virological response to antiretroviral treatment among immigrant and indigenous HIV infected patients.
AIDS Behav. 2012 Aug; 16(6):1681-9.AB

Abstract

We compared adherence to cART and virological response between indigenous and immigrant HIV-infected patients in the Netherlands, and investigated if a possible difference was related to a difference in the psychosocial variables: HIV-stigma, quality-of-life, depression and beliefs about medications. Psychosocial variables were assessed using validated questionnaires administered during a face-to-face interview. Adherence was assessed trough pharmacy-refill monitoring. We assessed associations between psychosocial variables and non-adherence and having detectable plasma viral load using logistic regression analyses. Two-hundred-two patients participated of whom 112 (55%) were immigrants. Viral load was detectable in 6% of indigenous patients and in 15% of the immigrants (P < 0.01). In multivariate analyses, higher HIV-stigma and prior virological failure were associated with non-adherence, and depressive symptoms, prior virological failure and non-adherence with detectable viral load. Our findings suggest that HIV-stigma and depressive symptoms may be targets for interventions aimed at improving adherence and virological response among indigenous and immigrant HIV-infected patients.

Authors+Show Affiliations

Department of Medical Psychology, Academic Medical Center, Amsterdam, The Netherlands.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

22198315

Citation

Sumari-de Boer, I Marion, et al. "HIV Stigma and Depressive Symptoms Are Related to Adherence and Virological Response to Antiretroviral Treatment Among Immigrant and Indigenous HIV Infected Patients." AIDS and Behavior, vol. 16, no. 6, 2012, pp. 1681-9.
Sumari-de Boer IM, Sprangers MA, Prins JM, et al. HIV stigma and depressive symptoms are related to adherence and virological response to antiretroviral treatment among immigrant and indigenous HIV infected patients. AIDS Behav. 2012;16(6):1681-9.
Sumari-de Boer, I. M., Sprangers, M. A., Prins, J. M., & Nieuwkerk, P. T. (2012). HIV stigma and depressive symptoms are related to adherence and virological response to antiretroviral treatment among immigrant and indigenous HIV infected patients. AIDS and Behavior, 16(6), 1681-9. https://doi.org/10.1007/s10461-011-0112-y
Sumari-de Boer IM, et al. HIV Stigma and Depressive Symptoms Are Related to Adherence and Virological Response to Antiretroviral Treatment Among Immigrant and Indigenous HIV Infected Patients. AIDS Behav. 2012;16(6):1681-9. PubMed PMID: 22198315.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - HIV stigma and depressive symptoms are related to adherence and virological response to antiretroviral treatment among immigrant and indigenous HIV infected patients. AU - Sumari-de Boer,I Marion, AU - Sprangers,Mirjam A G, AU - Prins,Jan M, AU - Nieuwkerk,Pythia T, PY - 2011/12/27/entrez PY - 2011/12/27/pubmed PY - 2012/9/27/medline SP - 1681 EP - 9 JF - AIDS and behavior JO - AIDS Behav VL - 16 IS - 6 N2 - We compared adherence to cART and virological response between indigenous and immigrant HIV-infected patients in the Netherlands, and investigated if a possible difference was related to a difference in the psychosocial variables: HIV-stigma, quality-of-life, depression and beliefs about medications. Psychosocial variables were assessed using validated questionnaires administered during a face-to-face interview. Adherence was assessed trough pharmacy-refill monitoring. We assessed associations between psychosocial variables and non-adherence and having detectable plasma viral load using logistic regression analyses. Two-hundred-two patients participated of whom 112 (55%) were immigrants. Viral load was detectable in 6% of indigenous patients and in 15% of the immigrants (P < 0.01). In multivariate analyses, higher HIV-stigma and prior virological failure were associated with non-adherence, and depressive symptoms, prior virological failure and non-adherence with detectable viral load. Our findings suggest that HIV-stigma and depressive symptoms may be targets for interventions aimed at improving adherence and virological response among indigenous and immigrant HIV-infected patients. SN - 1573-3254 UR - https://www.unboundmedicine.com/medline/citation/22198315/HIV_stigma_and_depressive_symptoms_are_related_to_adherence_and_virological_response_to_antiretroviral_treatment_among_immigrant_and_indigenous_HIV_infected_patients_ L2 - https://doi.org/10.1007/s10461-011-0112-y DB - PRIME DP - Unbound Medicine ER -