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Comparison of the validity of the Chinese versions of the Hypomania Symptom Checklist-32 (HCL-32) and Mood Disorder Questionnaire (MDQ) for the detection of bipolar disorder in medicated patients with major depressive disorder.
Int J Psychiatry Clin Pract. 2012 Jun; 16(2):132-7.IJ

Abstract

OBJECTIVE

The sensitivity and specificity of the Chinese versions of the Hypomania Symptom Checklist-32 (HCL-32) and Mood Disorder Questionnaire (MDQ) for detecting bipolar disorder in Taiwan were explored in this study.

METHODS

In total, 59 participants who were initially diagnosed with unipolar depression were recruited from an outpatient clinic and were screened for bipolar disorder using the HCL-32 and MDQ; each participant also underwent a diagnostic interview based on the Structured Clinical Interview for DSM-IV Axis disorder patients (SCID).

RESULTS

The results showed that the HCL-32 yielded the best combination of sensitivity (100%) and specificity (46.2%) at a cut-off point of 7/8, and the MDQ yielded the best combination of sensitivity (71.4%) and specificity (76.9%) at a cut-off point of 6/7.

CONCLUSION

The results of our study demonstrate that the HCL-32 and MDQ are of reasonable validity to distinguish between bipolar disorder and major depressive disorder. However small sample size may limit generalization of the results.

Authors+Show Affiliations

Department of Psychiatry, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Research Support, Non-U.S. Gov't
Validation Study

Language

eng

PubMed ID

22208673

Citation

Chou, Chia Chi, et al. "Comparison of the Validity of the Chinese Versions of the Hypomania Symptom Checklist-32 (HCL-32) and Mood Disorder Questionnaire (MDQ) for the Detection of Bipolar Disorder in Medicated Patients With Major Depressive Disorder." International Journal of Psychiatry in Clinical Practice, vol. 16, no. 2, 2012, pp. 132-7.
Chou CC, Lee IH, Yeh TL, et al. Comparison of the validity of the Chinese versions of the Hypomania Symptom Checklist-32 (HCL-32) and Mood Disorder Questionnaire (MDQ) for the detection of bipolar disorder in medicated patients with major depressive disorder. Int J Psychiatry Clin Pract. 2012;16(2):132-7.
Chou, C. C., Lee, I. H., Yeh, T. L., Chen, K. C., Chen, P. S., Chen, W. T., Lu, R. B., & Yang, Y. K. (2012). Comparison of the validity of the Chinese versions of the Hypomania Symptom Checklist-32 (HCL-32) and Mood Disorder Questionnaire (MDQ) for the detection of bipolar disorder in medicated patients with major depressive disorder. International Journal of Psychiatry in Clinical Practice, 16(2), 132-7. https://doi.org/10.3109/13651501.2011.644563
Chou CC, et al. Comparison of the Validity of the Chinese Versions of the Hypomania Symptom Checklist-32 (HCL-32) and Mood Disorder Questionnaire (MDQ) for the Detection of Bipolar Disorder in Medicated Patients With Major Depressive Disorder. Int J Psychiatry Clin Pract. 2012;16(2):132-7. PubMed PMID: 22208673.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Comparison of the validity of the Chinese versions of the Hypomania Symptom Checklist-32 (HCL-32) and Mood Disorder Questionnaire (MDQ) for the detection of bipolar disorder in medicated patients with major depressive disorder. AU - Chou,Chia Chi, AU - Lee,I Hui, AU - Yeh,Tzung Lieh, AU - Chen,Kao Chin, AU - Chen,Po See, AU - Chen,Wei Tseng, AU - Lu,Ru-Band, AU - Yang,Yen Kuang, Y1 - 2012/01/02/ PY - 2012/1/3/entrez PY - 2012/1/3/pubmed PY - 2012/7/24/medline SP - 132 EP - 7 JF - International journal of psychiatry in clinical practice JO - Int J Psychiatry Clin Pract VL - 16 IS - 2 N2 - OBJECTIVE: The sensitivity and specificity of the Chinese versions of the Hypomania Symptom Checklist-32 (HCL-32) and Mood Disorder Questionnaire (MDQ) for detecting bipolar disorder in Taiwan were explored in this study. METHODS: In total, 59 participants who were initially diagnosed with unipolar depression were recruited from an outpatient clinic and were screened for bipolar disorder using the HCL-32 and MDQ; each participant also underwent a diagnostic interview based on the Structured Clinical Interview for DSM-IV Axis disorder patients (SCID). RESULTS: The results showed that the HCL-32 yielded the best combination of sensitivity (100%) and specificity (46.2%) at a cut-off point of 7/8, and the MDQ yielded the best combination of sensitivity (71.4%) and specificity (76.9%) at a cut-off point of 6/7. CONCLUSION: The results of our study demonstrate that the HCL-32 and MDQ are of reasonable validity to distinguish between bipolar disorder and major depressive disorder. However small sample size may limit generalization of the results. SN - 1471-1788 UR - https://www.unboundmedicine.com/medline/citation/22208673/Comparison_of_the_validity_of_the_Chinese_versions_of_the_Hypomania_Symptom_Checklist_32__HCL_32__and_Mood_Disorder_Questionnaire__MDQ__for_the_detection_of_bipolar_disorder_in_medicated_patients_with_major_depressive_disorder_ L2 - https://www.tandfonline.com/doi/full/10.3109/13651501.2011.644563 DB - PRIME DP - Unbound Medicine ER -