Tags

Type your tag names separated by a space and hit enter

Shorter hospitalization trends among children with sickle cell disease.
Pediatr Blood Cancer. 2012 Oct; 59(4):679-84.PB

Abstract

BACKGROUND

Vaso-occlusive crises (VOC) contribute to frequent hospitalizations among children with sickle cell disease (SCD). The objective of this study was to determine whether length of stay (LOS) has decreased for VOC hospitalizations between 1997 and 2009.

PROCEDURE

We analyzed pediatric discharges (aged 0-18) with a primary or secondary diagnosis of SCD with crisis from the Kid's Inpatient Database (years 1997, 2003, and 2009), a nationally representative sample of pediatric hospital discharges. We conducted bivariate and multivariate, sample-weighted linear regression analyses to determine associations between independent variables (patient demographics, hospital characteristics, co-diagnoses, and procedures) and LOS.

RESULTS

Both the number (22,661-21,741) and proportion of VOC hospitalizations (0.34-0.29%) among all pediatric hospitalizations marginally decreased between 1997 and 2009 (P < 0.01). Mean LOS decreased from 4.59 to 4.21 days (P < 0.01). For all study years, older age was the only socio-demographic variable associated with longer LOS, controlling for other factors. Between 1997 and 2009, LOS decreased for all age categories, with the largest statistically significant reduction occurring among adolescents (5.69-4.76 days).

CONCLUSIONS

Nationally representative hospital data indicate modest but meaningful reductions in LOS for children with VOC over a 12-year period. Adolescents who typically have the greatest disease severity showed the largest reduction in LOS. However, adolescents continue to account for a large proportion of inpatient stays for VOC. These findings illustrate that the adolescent period is a critical time in the lifespan for targeted intervention.

Authors+Show Affiliations

Department of Pediatrics, Baylor College of Medicine, Texas Children's Cancer Center, Houston, Texas 77030, USA. Raphael@bcm.eduNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

22223395

Citation

Raphael, Jean L., et al. "Shorter Hospitalization Trends Among Children With Sickle Cell Disease." Pediatric Blood & Cancer, vol. 59, no. 4, 2012, pp. 679-84.
Raphael JL, Mueller BU, Kowalkowski MA, et al. Shorter hospitalization trends among children with sickle cell disease. Pediatr Blood Cancer. 2012;59(4):679-84.
Raphael, J. L., Mueller, B. U., Kowalkowski, M. A., & Oyeku, S. O. (2012). Shorter hospitalization trends among children with sickle cell disease. Pediatric Blood & Cancer, 59(4), 679-84. https://doi.org/10.1002/pbc.24065
Raphael JL, et al. Shorter Hospitalization Trends Among Children With Sickle Cell Disease. Pediatr Blood Cancer. 2012;59(4):679-84. PubMed PMID: 22223395.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Shorter hospitalization trends among children with sickle cell disease. AU - Raphael,Jean L, AU - Mueller,Brigitta U, AU - Kowalkowski,Marc A, AU - Oyeku,Suzette O, Y1 - 2012/01/04/ PY - 2011/10/03/received PY - 2011/12/05/accepted PY - 2012/1/7/entrez PY - 2012/1/10/pubmed PY - 2012/10/16/medline SP - 679 EP - 84 JF - Pediatric blood & cancer JO - Pediatr Blood Cancer VL - 59 IS - 4 N2 - BACKGROUND: Vaso-occlusive crises (VOC) contribute to frequent hospitalizations among children with sickle cell disease (SCD). The objective of this study was to determine whether length of stay (LOS) has decreased for VOC hospitalizations between 1997 and 2009. PROCEDURE: We analyzed pediatric discharges (aged 0-18) with a primary or secondary diagnosis of SCD with crisis from the Kid's Inpatient Database (years 1997, 2003, and 2009), a nationally representative sample of pediatric hospital discharges. We conducted bivariate and multivariate, sample-weighted linear regression analyses to determine associations between independent variables (patient demographics, hospital characteristics, co-diagnoses, and procedures) and LOS. RESULTS: Both the number (22,661-21,741) and proportion of VOC hospitalizations (0.34-0.29%) among all pediatric hospitalizations marginally decreased between 1997 and 2009 (P < 0.01). Mean LOS decreased from 4.59 to 4.21 days (P < 0.01). For all study years, older age was the only socio-demographic variable associated with longer LOS, controlling for other factors. Between 1997 and 2009, LOS decreased for all age categories, with the largest statistically significant reduction occurring among adolescents (5.69-4.76 days). CONCLUSIONS: Nationally representative hospital data indicate modest but meaningful reductions in LOS for children with VOC over a 12-year period. Adolescents who typically have the greatest disease severity showed the largest reduction in LOS. However, adolescents continue to account for a large proportion of inpatient stays for VOC. These findings illustrate that the adolescent period is a critical time in the lifespan for targeted intervention. SN - 1545-5017 UR - https://www.unboundmedicine.com/medline/citation/22223395/Shorter_hospitalization_trends_among_children_with_sickle_cell_disease_ L2 - https://doi.org/10.1002/pbc.24065 DB - PRIME DP - Unbound Medicine ER -