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Chemical fingerprint analysis of phenolics of Albizia chinensis based on ultra-performance LC-electrospray ionization-quadrupole time-of-flight mass spectrometry and antioxidant activity.
Nat Prod Commun. 2011 Nov; 6(11):1617-20.NP

Abstract

Albizia species have been shown to have anti-inflammatory and anti-allergic properties. However, efficient analytical methods for identification of their active constituents are still lacking. Ultra-performance liquid chromatography coupled with electrospray ionization-quadrupole time-of-flight mass spectrometry (UPLC-ESI-QTOF-MS) was used to study the phenolic composition of the ethanolic extracts of different parts (flowers, leaves, pods and bark) of A. chinensis. In addition, the antioxidant activity of the ethanolic extracts was evaluated by the 1,1-diphenyl-2-picryl hydrazyl (DPPH) free-radical and 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid (ABTS) radical cation scavenging methods. Four compounds were isolated from the ethanolic extract of the flowers and characterized by 1H and 13C NMR spectroscopy as quercetin-3-O-rhamnoside, quercetin, quercetin-3-O-arabinofuranoside, and myricetin-3-O-rhamnoside. Separation and quantification of the phenolics was accomplished using a reversed-phase BEH C18 column with the mobile phase of methanol-water (0.05% formic acid), and detection wavelengths of 360 and 254 nm.

Authors+Show Affiliations

Natural Plant Products Division, Institute of Himalayan Bioresource Technology (Council of Scientific and Industrial research), Palampur, Himachal Pradesh 176 061, India.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

22224274

Citation

Chaudhary, Abha, et al. "Chemical Fingerprint Analysis of Phenolics of Albizia Chinensis Based On Ultra-performance LC-electrospray Ionization-quadrupole Time-of-flight Mass Spectrometry and Antioxidant Activity." Natural Product Communications, vol. 6, no. 11, 2011, pp. 1617-20.
Chaudhary A, Kaur P, Kumar N, et al. Chemical fingerprint analysis of phenolics of Albizia chinensis based on ultra-performance LC-electrospray ionization-quadrupole time-of-flight mass spectrometry and antioxidant activity. Nat Prod Commun. 2011;6(11):1617-20.
Chaudhary, A., Kaur, P., Kumar, N., Singh, B., Awasthi, S., & Lal, B. (2011). Chemical fingerprint analysis of phenolics of Albizia chinensis based on ultra-performance LC-electrospray ionization-quadrupole time-of-flight mass spectrometry and antioxidant activity. Natural Product Communications, 6(11), 1617-20.
Chaudhary A, et al. Chemical Fingerprint Analysis of Phenolics of Albizia Chinensis Based On Ultra-performance LC-electrospray Ionization-quadrupole Time-of-flight Mass Spectrometry and Antioxidant Activity. Nat Prod Commun. 2011;6(11):1617-20. PubMed PMID: 22224274.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Chemical fingerprint analysis of phenolics of Albizia chinensis based on ultra-performance LC-electrospray ionization-quadrupole time-of-flight mass spectrometry and antioxidant activity. AU - Chaudhary,Abha, AU - Kaur,Pushpinder, AU - Kumar,Neeraj, AU - Singh,Bikram, AU - Awasthi,Shiv, AU - Lal,Brij, PY - 2012/1/10/entrez PY - 2012/1/10/pubmed PY - 2012/2/14/medline SP - 1617 EP - 20 JF - Natural product communications JO - Nat Prod Commun VL - 6 IS - 11 N2 - Albizia species have been shown to have anti-inflammatory and anti-allergic properties. However, efficient analytical methods for identification of their active constituents are still lacking. Ultra-performance liquid chromatography coupled with electrospray ionization-quadrupole time-of-flight mass spectrometry (UPLC-ESI-QTOF-MS) was used to study the phenolic composition of the ethanolic extracts of different parts (flowers, leaves, pods and bark) of A. chinensis. In addition, the antioxidant activity of the ethanolic extracts was evaluated by the 1,1-diphenyl-2-picryl hydrazyl (DPPH) free-radical and 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid (ABTS) radical cation scavenging methods. Four compounds were isolated from the ethanolic extract of the flowers and characterized by 1H and 13C NMR spectroscopy as quercetin-3-O-rhamnoside, quercetin, quercetin-3-O-arabinofuranoside, and myricetin-3-O-rhamnoside. Separation and quantification of the phenolics was accomplished using a reversed-phase BEH C18 column with the mobile phase of methanol-water (0.05% formic acid), and detection wavelengths of 360 and 254 nm. SN - 1934-578X UR - https://www.unboundmedicine.com/medline/citation/22224274/Chemical_fingerprint_analysis_of_phenolics_of_Albizia_chinensis_based_on_ultra_performance_LC_electrospray_ionization_quadrupole_time_of_flight_mass_spectrometry_and_antioxidant_activity_ L2 - https://medlineplus.gov/antioxidants.html DB - PRIME DP - Unbound Medicine ER -