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SF-6D values stratified by specific diagnostic indication.
Spine (Phila Pa 1976). 2012 Jun 01; 37(13):E804-8.S

Abstract

STUDY DESIGN

Longitudinal cohort.

OBJECTIVE

To present Oswestry Disability Index scores and SF-6D utility values among patients with different diagnostic etiologies who underwent fusion surgery.

SUMMARY OF BACKGROUND DATA

Several studies have increased our understanding of health-related quality-of-life measures in patients with low back pain. With rising health care costs, cost-utility analysis is increasingly used by decision makers. Thus, clinicians and researchers need to understand the psychometrics and clinical importance of health state utility values in patients with spine disorders.

METHODS

A total of 1104 patients who had decompression and lumbar fusion with complete data to compute the SF-6D score at baseline and 2-year follow-up were identified. Primary surgical cases were classified as disc pathology (n = 200), spondylolisthesis (n = 288), instability (n = 43), stenosis (n = 134), or scoliosis (n = 44). Revision cases were classified as nonunion (n = 94), adjacent-level degeneration (n = 98), or postdiscectomy revision (n = 203). Baseline SF-6D and change in SF-6D scores at 2 years were compared among the groups as well as primary versus revision cases.

RESULTS

There were 674 women and 430 men. The mean age at surgery was 56.65 ± 12.7 years. There were 220 (19.9%) smokers. The worst mean baseline SF-6D score was in patients with nonunion (0.492), followed by disc pathology (0.493), adjacent-level degeneration (0.494), postdiscectomy revision (0.499), stenosis (0.504), instability (0.512), spondylolisthesis (0.520), and scoliosis (0.530). There was a statistically significant difference in baseline SF-6D score among the different groups (P = 0.002). The mean change in SF-6D score was greatest in patients with stenosis (0.088), followed by spondylolisthesis (0.085), scoliosis (0.076), disc pathology (0.076), instability (0.073), postdiscectomy revision (0.070), adjacent-level degeneration (0.066), and nonunion (0.050). There was no statistically significant difference in change in SF-6D score among the different groups (P = 0.096). However, revision cases had statistically significantly smaller gains in SF-6D score (0.064) than primary cases (0.082, P = 0.012).

CONCLUSION

Patients with lumbar degenerative disorders have health state values similar to patients with chronic renal disease, Crohn's disease, or coronary artery disease. Health state values of patients with different indications for surgery differ at baseline and after surgery. Revision cases have worse baseline SF-6D scores and less improvement in scores at 2 years after surgery than primary cases. Further studies are needed to gain a greater understanding of health state utility values in patients with lumbar degenerative disorders.

Authors+Show Affiliations

Norton Leatherman Spine Center, Louisville, KY 40202, USA. leah.carreon@nortonhealthcare.orgNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

22228327

Citation

Carreon, Leah Y., et al. "SF-6D Values Stratified By Specific Diagnostic Indication." Spine, vol. 37, no. 13, 2012, pp. E804-8.
Carreon LY, Djurasovic M, Canan CE, et al. SF-6D values stratified by specific diagnostic indication. Spine (Phila Pa 1976). 2012;37(13):E804-8.
Carreon, L. Y., Djurasovic, M., Canan, C. E., Burke, L. O., & Glassman, S. D. (2012). SF-6D values stratified by specific diagnostic indication. Spine, 37(13), E804-8. https://doi.org/10.1097/BRS.0b013e318247821b
Carreon LY, et al. SF-6D Values Stratified By Specific Diagnostic Indication. Spine (Phila Pa 1976). 2012 Jun 1;37(13):E804-8. PubMed PMID: 22228327.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - SF-6D values stratified by specific diagnostic indication. AU - Carreon,Leah Y, AU - Djurasovic,Mladen, AU - Canan,Chelsea E, AU - Burke,Lauren O, AU - Glassman,Steven D, PY - 2012/1/10/entrez PY - 2012/1/10/pubmed PY - 2012/10/4/medline SP - E804 EP - 8 JF - Spine JO - Spine (Phila Pa 1976) VL - 37 IS - 13 N2 - STUDY DESIGN: Longitudinal cohort. OBJECTIVE: To present Oswestry Disability Index scores and SF-6D utility values among patients with different diagnostic etiologies who underwent fusion surgery. SUMMARY OF BACKGROUND DATA: Several studies have increased our understanding of health-related quality-of-life measures in patients with low back pain. With rising health care costs, cost-utility analysis is increasingly used by decision makers. Thus, clinicians and researchers need to understand the psychometrics and clinical importance of health state utility values in patients with spine disorders. METHODS: A total of 1104 patients who had decompression and lumbar fusion with complete data to compute the SF-6D score at baseline and 2-year follow-up were identified. Primary surgical cases were classified as disc pathology (n = 200), spondylolisthesis (n = 288), instability (n = 43), stenosis (n = 134), or scoliosis (n = 44). Revision cases were classified as nonunion (n = 94), adjacent-level degeneration (n = 98), or postdiscectomy revision (n = 203). Baseline SF-6D and change in SF-6D scores at 2 years were compared among the groups as well as primary versus revision cases. RESULTS: There were 674 women and 430 men. The mean age at surgery was 56.65 ± 12.7 years. There were 220 (19.9%) smokers. The worst mean baseline SF-6D score was in patients with nonunion (0.492), followed by disc pathology (0.493), adjacent-level degeneration (0.494), postdiscectomy revision (0.499), stenosis (0.504), instability (0.512), spondylolisthesis (0.520), and scoliosis (0.530). There was a statistically significant difference in baseline SF-6D score among the different groups (P = 0.002). The mean change in SF-6D score was greatest in patients with stenosis (0.088), followed by spondylolisthesis (0.085), scoliosis (0.076), disc pathology (0.076), instability (0.073), postdiscectomy revision (0.070), adjacent-level degeneration (0.066), and nonunion (0.050). There was no statistically significant difference in change in SF-6D score among the different groups (P = 0.096). However, revision cases had statistically significantly smaller gains in SF-6D score (0.064) than primary cases (0.082, P = 0.012). CONCLUSION: Patients with lumbar degenerative disorders have health state values similar to patients with chronic renal disease, Crohn's disease, or coronary artery disease. Health state values of patients with different indications for surgery differ at baseline and after surgery. Revision cases have worse baseline SF-6D scores and less improvement in scores at 2 years after surgery than primary cases. Further studies are needed to gain a greater understanding of health state utility values in patients with lumbar degenerative disorders. SN - 1528-1159 UR - https://www.unboundmedicine.com/medline/citation/22228327/SF_6D_values_stratified_by_specific_diagnostic_indication_ L2 - https://doi.org/10.1097/BRS.0b013e318247821b DB - PRIME DP - Unbound Medicine ER -