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Nonalcoholic fatty liver disease in pediatric patients.
JPEN J Parenter Enteral Nutr. 2012 Jan; 36(1 Suppl):43S-8S.JJ

Abstract

Nonalcoholic fatty liver disease is a spectrum of liver disease ranging from simple hepatic steatosis to steatohepatitis, hepatic fibrosis, and cirrhosis. It is highly associated with obesity and insulin resistance, and with the dramatic increase in childhood and adolescent obesity, it has become the most common form of chronic liver disease in these age groups. Genetic and environmental factors both appear to play a role in the development of nonalcoholic fatty liver disease. There is currently no established effective therapy, and decreasing the prevalence of this disorder will require a reduction in the current obesity epidemic.

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    Authors+Show Affiliations

    Sinatra FR
    Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA. sinatra@usc.edu

    MeSH

    ChildChronic DiseaseClinical Trials as TopicFatty LiverHumansInsulin ResistanceLiver CirrhosisNon-alcoholic Fatty Liver DiseaseObesityPrevalence

    Pub Type(s)

    Journal Article
    Review

    Language

    eng

    PubMed ID

    22237875

    Citation

    Sinatra, Frank R.. "Nonalcoholic Fatty Liver Disease in Pediatric Patients." JPEN. Journal of Parenteral and Enteral Nutrition, vol. 36, no. 1 Suppl, 2012, 43S-8S.
    Sinatra FR. Nonalcoholic fatty liver disease in pediatric patients. JPEN J Parenter Enteral Nutr. 2012;36(1 Suppl):43S-8S.
    Sinatra, F. R. (2012). Nonalcoholic fatty liver disease in pediatric patients. JPEN. Journal of Parenteral and Enteral Nutrition, 36(1 Suppl), 43S-8S. https://doi.org/10.1177/0148607111421610
    Sinatra FR. Nonalcoholic Fatty Liver Disease in Pediatric Patients. JPEN J Parenter Enteral Nutr. 2012;36(1 Suppl):43S-8S. PubMed PMID: 22237875.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Nonalcoholic fatty liver disease in pediatric patients. A1 - Sinatra,Frank R, PY - 2012/1/13/entrez PY - 2012/1/18/pubmed PY - 2012/5/4/medline SP - 43S EP - 8S JF - JPEN. Journal of parenteral and enteral nutrition JO - JPEN J Parenter Enteral Nutr VL - 36 IS - 1 Suppl N2 - Nonalcoholic fatty liver disease is a spectrum of liver disease ranging from simple hepatic steatosis to steatohepatitis, hepatic fibrosis, and cirrhosis. It is highly associated with obesity and insulin resistance, and with the dramatic increase in childhood and adolescent obesity, it has become the most common form of chronic liver disease in these age groups. Genetic and environmental factors both appear to play a role in the development of nonalcoholic fatty liver disease. There is currently no established effective therapy, and decreasing the prevalence of this disorder will require a reduction in the current obesity epidemic. SN - 1941-2444 UR - https://www.unboundmedicine.com/medline/citation/22237875/Nonalcoholic_fatty_liver_disease_in_pediatric_patients_ L2 - https://doi.org/10.1177/0148607111421610 DB - PRIME DP - Unbound Medicine ER -