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Outbreaks of human monkeypox after cessation of smallpox vaccination.
Trends Microbiol. 2012 Feb; 20(2):80-7.TM

Abstract

The recent observation of a surge in human monkeypox in the Democratic Republic of the Congo (DRC) prompts the question of whether cessation of smallpox vaccination is driving the phenomenon, and if so, why is re-emergence not universal throughout the historic geographic range of the virus? Research addressing the virus's mechanisms for immune evasion and induction, as well as that directed at elucidating the genes involved in pathogenesis in different viral lineages (West African vs Congo Basin), provide insights to help explain why emergence appears to be geographically limited. Novel vaccines offer one solution to curtail the spread of this disease.

Authors+Show Affiliations

Division of High-consequence Pathogens and Pathology, US Centers for Disease Control and Prevention, 1600 Clifton Rd NE, Mailstop G-43, Atlanta, GA 30333, USA.No affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

22239910

Citation

Reynolds, Mary G., and Inger K. Damon. "Outbreaks of Human Monkeypox After Cessation of Smallpox Vaccination." Trends in Microbiology, vol. 20, no. 2, 2012, pp. 80-7.
Reynolds MG, Damon IK. Outbreaks of human monkeypox after cessation of smallpox vaccination. Trends Microbiol. 2012;20(2):80-7.
Reynolds, M. G., & Damon, I. K. (2012). Outbreaks of human monkeypox after cessation of smallpox vaccination. Trends in Microbiology, 20(2), 80-7. https://doi.org/10.1016/j.tim.2011.12.001
Reynolds MG, Damon IK. Outbreaks of Human Monkeypox After Cessation of Smallpox Vaccination. Trends Microbiol. 2012;20(2):80-7. PubMed PMID: 22239910.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Outbreaks of human monkeypox after cessation of smallpox vaccination. AU - Reynolds,Mary G, AU - Damon,Inger K, Y1 - 2012/01/10/ PY - 2011/09/30/received PY - 2011/12/02/revised PY - 2011/12/08/accepted PY - 2012/1/14/entrez PY - 2012/1/14/pubmed PY - 2012/6/26/medline SP - 80 EP - 7 JF - Trends in microbiology JO - Trends Microbiol VL - 20 IS - 2 N2 - The recent observation of a surge in human monkeypox in the Democratic Republic of the Congo (DRC) prompts the question of whether cessation of smallpox vaccination is driving the phenomenon, and if so, why is re-emergence not universal throughout the historic geographic range of the virus? Research addressing the virus's mechanisms for immune evasion and induction, as well as that directed at elucidating the genes involved in pathogenesis in different viral lineages (West African vs Congo Basin), provide insights to help explain why emergence appears to be geographically limited. Novel vaccines offer one solution to curtail the spread of this disease. SN - 1878-4380 UR - https://www.unboundmedicine.com/medline/citation/22239910/Outbreaks_of_human_monkeypox_after_cessation_of_smallpox_vaccination_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0966-842X(11)00212-5 DB - PRIME DP - Unbound Medicine ER -