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Better to give than to take? Interactive social decision-making in severe major depressive disorder.
J Affect Disord. 2012 Mar; 137(1-3):98-105.JA

Abstract

BACKGROUND

Although recent studies focusing on major depressive disorder (MDD) suggest altered social decision-making, studies using the Ultimatum Game (UG) in patients with severe, clinical MDD do not exist. Moreover, all aforementioned studies so far focused on responder behavior and thus fairness considerations; to this date, no one investigated social interactive behavior which involves proposer behavior possibly requiring second-order mentalizing as well.

METHODS

Thirty-nine MDD patients and 22 healthy controls played a modified UG, both in the roles of responder and proposer against the same partner.

RESULTS

MDD patients accepted both fair and unfair offers as many times as the healthy controls in their role as responder. Importantly, however, in the role of proposer MDD patients offered significantly more than the control group did.

LIMITATIONS

Most patients were treated with psychotropic medication.

CONCLUSIONS

Responder behavior demonstrates that MDD patients are capable of making social decisions on fairness considerations in the same way as healthy controls do. The observed proposer behavior, however, could indicate that MDD patients are more focused on avoiding rejection. These findings provide unique evidence that social decision-making--as studied in a realistic context--is disturbed in MDD.

Authors+Show Affiliations

Collaborative Antwerp Psychiatric Research Institute (CAPRI), University of Antwerp, Universiteitsplein 1, Antwerp, Belgium. marianne.destoop@ua.ac.beNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

22240086

Citation

Destoop, Marianne, et al. "Better to Give Than to Take? Interactive Social Decision-making in Severe Major Depressive Disorder." Journal of Affective Disorders, vol. 137, no. 1-3, 2012, pp. 98-105.
Destoop M, Schrijvers D, De Grave C, et al. Better to give than to take? Interactive social decision-making in severe major depressive disorder. J Affect Disord. 2012;137(1-3):98-105.
Destoop, M., Schrijvers, D., De Grave, C., Sabbe, B., & De Bruijn, E. R. (2012). Better to give than to take? Interactive social decision-making in severe major depressive disorder. Journal of Affective Disorders, 137(1-3), 98-105. https://doi.org/10.1016/j.jad.2011.12.010
Destoop M, et al. Better to Give Than to Take? Interactive Social Decision-making in Severe Major Depressive Disorder. J Affect Disord. 2012;137(1-3):98-105. PubMed PMID: 22240086.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Better to give than to take? Interactive social decision-making in severe major depressive disorder. AU - Destoop,Marianne, AU - Schrijvers,Didier, AU - De Grave,Carmen, AU - Sabbe,Bernard, AU - De Bruijn,Ellen R A, Y1 - 2012/01/10/ PY - 2011/10/19/received PY - 2011/12/12/revised PY - 2011/12/13/accepted PY - 2012/1/14/entrez PY - 2012/1/14/pubmed PY - 2012/4/28/medline SP - 98 EP - 105 JF - Journal of affective disorders JO - J Affect Disord VL - 137 IS - 1-3 N2 - BACKGROUND: Although recent studies focusing on major depressive disorder (MDD) suggest altered social decision-making, studies using the Ultimatum Game (UG) in patients with severe, clinical MDD do not exist. Moreover, all aforementioned studies so far focused on responder behavior and thus fairness considerations; to this date, no one investigated social interactive behavior which involves proposer behavior possibly requiring second-order mentalizing as well. METHODS: Thirty-nine MDD patients and 22 healthy controls played a modified UG, both in the roles of responder and proposer against the same partner. RESULTS: MDD patients accepted both fair and unfair offers as many times as the healthy controls in their role as responder. Importantly, however, in the role of proposer MDD patients offered significantly more than the control group did. LIMITATIONS: Most patients were treated with psychotropic medication. CONCLUSIONS: Responder behavior demonstrates that MDD patients are capable of making social decisions on fairness considerations in the same way as healthy controls do. The observed proposer behavior, however, could indicate that MDD patients are more focused on avoiding rejection. These findings provide unique evidence that social decision-making--as studied in a realistic context--is disturbed in MDD. SN - 1573-2517 UR - https://www.unboundmedicine.com/medline/citation/22240086/Better_to_give_than_to_take_Interactive_social_decision_making_in_severe_major_depressive_disorder_ DB - PRIME DP - Unbound Medicine ER -