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First coronary heart disease event rates in relation to major risk factors: Quebec cardiovascular study.
Can J Cardiol. 1990 Sep; 6(7):274-80.CJ

Abstract

The incidence of first coronary heart disease (CHD) events was evaluated prospectively in relation to the baseline measurements of systolic and diastolic blood pressure, serum cholesterol, smoking status and education in a cohort of 4576 Quebec men aged 35 to 64 and free from CHD at entry in 1974. From 1974 to 1986, 603 first CHD events were documented. The most frequent first manifestation was angina (6.7/1000 person-years) followed by nonfatal myocardial infarction (4.7/1000) and CHD death 2.2/1000). There was a positive relationship between the first CHD event and systolic (Z = 4.67) and diastolic (Z = 6.50) blood pressure. This relation was observed for angina, nonfatal myocardial infarction and CHD death. Serum cholesterol was also related to all events (Z = 4.99) but more specifically to angina and nonfatal myocardial infarction. Cigarette smoking was significantly related to first CHD manifestations. This relationship for specific CHD events was observed in men who smoked more than 20 cigarettes per day. Men who discontinued smoking one year before the study had a risk not different from those who never smoked. No relationship was observed between years of schooling and CHD events. Blood pressure, cholesterol and smoking constituted nearly two-thirds of the attributable risk of first CHD events.

Authors+Show Affiliations

Department of Medicine, Faculty of Medicine, Laval University, Quebec.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

2224616

Citation

Dagenais, G R., et al. "First Coronary Heart Disease Event Rates in Relation to Major Risk Factors: Quebec Cardiovascular Study." The Canadian Journal of Cardiology, vol. 6, no. 7, 1990, pp. 274-80.
Dagenais GR, Robitaille NM, Lupien PJ, et al. First coronary heart disease event rates in relation to major risk factors: Quebec cardiovascular study. Can J Cardiol. 1990;6(7):274-80.
Dagenais, G. R., Robitaille, N. M., Lupien, P. J., Christen, A., Gingras, S., Moorjani, S., Meyer, F., & Rochon, J. (1990). First coronary heart disease event rates in relation to major risk factors: Quebec cardiovascular study. The Canadian Journal of Cardiology, 6(7), 274-80.
Dagenais GR, et al. First Coronary Heart Disease Event Rates in Relation to Major Risk Factors: Quebec Cardiovascular Study. Can J Cardiol. 1990;6(7):274-80. PubMed PMID: 2224616.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - First coronary heart disease event rates in relation to major risk factors: Quebec cardiovascular study. AU - Dagenais,G R, AU - Robitaille,N M, AU - Lupien,P J, AU - Christen,A, AU - Gingras,S, AU - Moorjani,S, AU - Meyer,F, AU - Rochon,J, PY - 1990/9/1/pubmed PY - 1990/9/1/medline PY - 1990/9/1/entrez SP - 274 EP - 80 JF - The Canadian journal of cardiology JO - Can J Cardiol VL - 6 IS - 7 N2 - The incidence of first coronary heart disease (CHD) events was evaluated prospectively in relation to the baseline measurements of systolic and diastolic blood pressure, serum cholesterol, smoking status and education in a cohort of 4576 Quebec men aged 35 to 64 and free from CHD at entry in 1974. From 1974 to 1986, 603 first CHD events were documented. The most frequent first manifestation was angina (6.7/1000 person-years) followed by nonfatal myocardial infarction (4.7/1000) and CHD death 2.2/1000). There was a positive relationship between the first CHD event and systolic (Z = 4.67) and diastolic (Z = 6.50) blood pressure. This relation was observed for angina, nonfatal myocardial infarction and CHD death. Serum cholesterol was also related to all events (Z = 4.99) but more specifically to angina and nonfatal myocardial infarction. Cigarette smoking was significantly related to first CHD manifestations. This relationship for specific CHD events was observed in men who smoked more than 20 cigarettes per day. Men who discontinued smoking one year before the study had a risk not different from those who never smoked. No relationship was observed between years of schooling and CHD events. Blood pressure, cholesterol and smoking constituted nearly two-thirds of the attributable risk of first CHD events. SN - 0828-282X UR - https://www.unboundmedicine.com/medline/citation/2224616/First_coronary_heart_disease_event_rates_in_relation_to_major_risk_factors:_Quebec_cardiovascular_study_ L2 - http://www.diseaseinfosearch.org/result/130 DB - PRIME DP - Unbound Medicine ER -