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Copper and selenium status of healthy pregnant women in Enugu, southeastern Nigeria.
Niger J Clin Pract. 2011 Oct-Dec; 14(4):408-12.NJ

Abstract

BACKGROUND

Copper and selenium are important trace elements in man. They function as antioxidants and play roles in oxido-reductase reactions. Several imported multivitamin preparations are given to our women during pregnancy and lactation to correct possible deficiencies.

OBJECTIVE

The aim of the study is to determine the serum level of these micronutrients (selenium and copper) in a cross section of pregnant women in Enugu, southeastern Nigeria.

MATERIALS AND METHODS

A cross section of 130 healthy pregnant women at different trimesters of pregnancy and 30 non-pregnant controls were selected from two health facilities in Enugu, southeastern Nigeria. Serum from the samples collected was assayed for copper and selenium using atomic absorption spectrophotometer.

RESULTS

The mean copper level increased (P = 0.018), while the selenium level decreased (P < 0.0001) as pregnancy advanced.

CONCLUSION

High copper levels indicate that supplementation should not be undertaken during normal pregnancy. Dietary intake should be modified to ensure optimal selenium levels during pregnancy.

Authors+Show Affiliations

Department of Physiology/Obstetrics and Gynecology, University of Nigeria, Enugu campus, Nigeria. uchenwagha@yahoo.comNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

22248939

Citation

Nwagha, U I., et al. "Copper and Selenium Status of Healthy Pregnant Women in Enugu, Southeastern Nigeria." Nigerian Journal of Clinical Practice, vol. 14, no. 4, 2011, pp. 408-12.
Nwagha UI, Ogbodo SO, Nwogu-Ikojo EE, et al. Copper and selenium status of healthy pregnant women in Enugu, southeastern Nigeria. Niger J Clin Pract. 2011;14(4):408-12.
Nwagha, U. I., Ogbodo, S. O., Nwogu-Ikojo, E. E., Ibegbu, D. M., Ejezie, F. E., Nwagha, T. U., & Dim, C. C. (2011). Copper and selenium status of healthy pregnant women in Enugu, southeastern Nigeria. Nigerian Journal of Clinical Practice, 14(4), 408-12. https://doi.org/10.4103/1119-3077.91745
Nwagha UI, et al. Copper and Selenium Status of Healthy Pregnant Women in Enugu, Southeastern Nigeria. Niger J Clin Pract. 2011 Oct-Dec;14(4):408-12. PubMed PMID: 22248939.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Copper and selenium status of healthy pregnant women in Enugu, southeastern Nigeria. AU - Nwagha,U I, AU - Ogbodo,S O, AU - Nwogu-Ikojo,E E, AU - Ibegbu,D M, AU - Ejezie,F E, AU - Nwagha,T U, AU - Dim,C C, PY - 2012/1/18/entrez PY - 2012/1/18/pubmed PY - 2012/5/17/medline SP - 408 EP - 12 JF - Nigerian journal of clinical practice JO - Niger J Clin Pract VL - 14 IS - 4 N2 - BACKGROUND: Copper and selenium are important trace elements in man. They function as antioxidants and play roles in oxido-reductase reactions. Several imported multivitamin preparations are given to our women during pregnancy and lactation to correct possible deficiencies. OBJECTIVE: The aim of the study is to determine the serum level of these micronutrients (selenium and copper) in a cross section of pregnant women in Enugu, southeastern Nigeria. MATERIALS AND METHODS: A cross section of 130 healthy pregnant women at different trimesters of pregnancy and 30 non-pregnant controls were selected from two health facilities in Enugu, southeastern Nigeria. Serum from the samples collected was assayed for copper and selenium using atomic absorption spectrophotometer. RESULTS: The mean copper level increased (P = 0.018), while the selenium level decreased (P < 0.0001) as pregnancy advanced. CONCLUSION: High copper levels indicate that supplementation should not be undertaken during normal pregnancy. Dietary intake should be modified to ensure optimal selenium levels during pregnancy. SN - 1119-3077 UR - https://www.unboundmedicine.com/medline/citation/22248939/Copper_and_selenium_status_of_healthy_pregnant_women_in_Enugu_southeastern_Nigeria_ L2 - http://www.njcponline.com/article.asp?issn=1119-3077;year=2011;volume=14;issue=4;spage=408;epage=412;aulast=Nwagha DB - PRIME DP - Unbound Medicine ER -