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Antioxidant phenolic compounds from the stems of Entada phaseoloides.
Chem Biodivers. 2012 Jan; 9(1):68-79.CB

Abstract

The EtOH extract of the stems of Entada phaseoloides displayed potent antioxidant activity when assessed by the 1,1-diphenyl-2-picrylhydrazyl (DPPH) and 2,2'-azinobis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) radical-scavenging, reducing power, β-carotene-bleaching, and superoxide radical-scavenging analyses. Fractionation of the EtOH extracts showed that the AcOEt fraction is the most active, followed by the H(2) O fraction, while BuOH fraction was least active. Further activity-guided fractionation studies on the active fractions resulted in the isolation of 22 compounds. The identities of these compounds were established based on extensive spectroscopic studies. Furthermore, the antioxidant activities of the isolated compounds were evaluated by using the above-mentioned five assays. The results demonstrated that the EtOH extract of E. phaseoloides stems exhibits an excellent antioxidant activity and thus presents a great potential as a source of natural antioxidants.

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Publisher Full Text (DOI)

Authors+Show Affiliations

Dong Y
School of Pharmacy, Shanghai Jiao Tong University, No. 800 Dongchuan Road, Minhang District, Shanghai 200240, P. R. China.
Shi H
No affiliation info available
Yang H
No affiliation info available
Peng Y
No affiliation info available
Wang M
No affiliation info available
Li X
No affiliation info available

MeSH

AntioxidantsFabaceaePhenolsPlant Stems

Pub Type(s)

Journal Article

Language

eng

PubMed ID

22253104

Citation

Dong, Yuqiong, et al. "Antioxidant Phenolic Compounds From the Stems of Entada Phaseoloides." Chemistry & Biodiversity, vol. 9, no. 1, 2012, pp. 68-79.
Dong Y, Shi H, Yang H, et al. Antioxidant phenolic compounds from the stems of Entada phaseoloides. Chem Biodivers. 2012;9(1):68-79.
Dong, Y., Shi, H., Yang, H., Peng, Y., Wang, M., & Li, X. (2012). Antioxidant phenolic compounds from the stems of Entada phaseoloides. Chemistry & Biodiversity, 9(1), 68-79. https://doi.org/10.1002/cbdv.201100002
Dong Y, et al. Antioxidant Phenolic Compounds From the Stems of Entada Phaseoloides. Chem Biodivers. 2012;9(1):68-79. PubMed PMID: 22253104.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Antioxidant phenolic compounds from the stems of Entada phaseoloides. AU - Dong,Yuqiong, AU - Shi,Haiming, AU - Yang,Haisha, AU - Peng,Yunhua, AU - Wang,Mengyue, AU - Li,Xiaobo, PY - 2012/1/19/entrez PY - 2012/1/19/pubmed PY - 2012/5/15/medline SP - 68 EP - 79 JF - Chemistry & biodiversity JO - Chem Biodivers VL - 9 IS - 1 N2 - The EtOH extract of the stems of Entada phaseoloides displayed potent antioxidant activity when assessed by the 1,1-diphenyl-2-picrylhydrazyl (DPPH) and 2,2'-azinobis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) radical-scavenging, reducing power, β-carotene-bleaching, and superoxide radical-scavenging analyses. Fractionation of the EtOH extracts showed that the AcOEt fraction is the most active, followed by the H(2) O fraction, while BuOH fraction was least active. Further activity-guided fractionation studies on the active fractions resulted in the isolation of 22 compounds. The identities of these compounds were established based on extensive spectroscopic studies. Furthermore, the antioxidant activities of the isolated compounds were evaluated by using the above-mentioned five assays. The results demonstrated that the EtOH extract of E. phaseoloides stems exhibits an excellent antioxidant activity and thus presents a great potential as a source of natural antioxidants. SN - 1612-1880 UR - https://www.unboundmedicine.com/medline/citation/22253104/Antioxidant_phenolic_compounds_from_the_stems_of_Entada_phaseoloides_ L2 - https://doi.org/10.1002/cbdv.201100002 DB - PRIME DP - Unbound Medicine ER -