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[Chemical constituents from root bark of Tripterygium hypoglaucum].
Zhongguo Zhong Yao Za Zhi. 2011 Sep; 36(18):2503-6.ZZ

Abstract

OBJECTIVE

To investigate chemical constituents of the root bark of Tripterygium hypoglaucum.

METHOD

Compounds were isolated by column chromatography on silica gel and Sephadex LH-20, and their structures were identified on the basis of spectral data (MS, 1H-NMR and 13C-NMR).

RESULT

Twelve compounds were isolated and identified as friedelin (1), 3-oxo-olean-9(11),12-diene (2), canophyllal (3), 3-acetoxy oleanolic acid (4), triptophenolide (5), triptonoterpene methyl ether (6), tricosanoic acid (7), beta-sitosterol (8), stearic acid (9), glut-5-en-3beta,28-diol (10), palmitic acid (11) and daucostorol (12).

CONCLUSION

Compounds 1, 2, 3, 7 and 10 were isolated from T. hypoglaucum and 7 from the genus Tripterygium for the first time.

Authors+Show Affiliations

Liu Z
Institute of Medicinal Plant Development, Chinese Academy of Medical Science & Peking Union Medical College, Beijing 100193, China.
Zhao R
No affiliation info available
Zou Z
No affiliation info available

MeSH

ChromatographyDiterpenesFatty Acids, UnsaturatedMagnetic Resonance SpectroscopyMass SpectrometryOleanolic AcidOrganic ChemicalsPalmitic AcidPlant RootsSitosterolsStearic AcidsTripterygiumTriterpenes

Pub Type(s)

Journal Article

Language

chi

PubMed ID

22256754

Citation

Liu, Zhenzhen, et al. "[Chemical Constituents From Root Bark of Tripterygium Hypoglaucum]." Zhongguo Zhong Yao Za Zhi = Zhongguo Zhongyao Zazhi = China Journal of Chinese Materia Medica, vol. 36, no. 18, 2011, pp. 2503-6.
Liu Z, Zhao R, Zou Z. [Chemical constituents from root bark of Tripterygium hypoglaucum]. Zhongguo Zhong Yao Za Zhi. 2011;36(18):2503-6.
Liu, Z., Zhao, R., & Zou, Z. (2011). [Chemical constituents from root bark of Tripterygium hypoglaucum]. Zhongguo Zhong Yao Za Zhi = Zhongguo Zhongyao Zazhi = China Journal of Chinese Materia Medica, 36(18), 2503-6.
Liu Z, Zhao R, Zou Z. [Chemical Constituents From Root Bark of Tripterygium Hypoglaucum]. Zhongguo Zhong Yao Za Zhi. 2011;36(18):2503-6. PubMed PMID: 22256754.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Chemical constituents from root bark of Tripterygium hypoglaucum]. AU - Liu,Zhenzhen, AU - Zhao,Ronghua, AU - Zou,Zhongmei, PY - 2012/1/20/entrez PY - 2012/1/20/pubmed PY - 2012/2/14/medline SP - 2503 EP - 6 JF - Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica JO - Zhongguo Zhong Yao Za Zhi VL - 36 IS - 18 N2 - OBJECTIVE: To investigate chemical constituents of the root bark of Tripterygium hypoglaucum. METHOD: Compounds were isolated by column chromatography on silica gel and Sephadex LH-20, and their structures were identified on the basis of spectral data (MS, 1H-NMR and 13C-NMR). RESULT: Twelve compounds were isolated and identified as friedelin (1), 3-oxo-olean-9(11),12-diene (2), canophyllal (3), 3-acetoxy oleanolic acid (4), triptophenolide (5), triptonoterpene methyl ether (6), tricosanoic acid (7), beta-sitosterol (8), stearic acid (9), glut-5-en-3beta,28-diol (10), palmitic acid (11) and daucostorol (12). CONCLUSION: Compounds 1, 2, 3, 7 and 10 were isolated from T. hypoglaucum and 7 from the genus Tripterygium for the first time. SN - 1001-5302 UR - https://www.unboundmedicine.com/medline/citation/22256754/[Chemical_constituents_from_root_bark_of_Tripterygium_hypoglaucum]_ DB - PRIME DP - Unbound Medicine ER -