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[Triterpenes and sterols from Nauclea latifolia].
Zhongguo Zhong Yao Za Zhi. 2011 Sep; 36(18):2511-4.ZZ

Abstract

OBJECTIVE

To investigate the chemical constituents of Nauclea latifolia, which is an African folk medicine and collected from Guinea.

METHOD

The chemical constituents were isolated by silica gel and Sephadex LH-20 column chromatographies, and structurally elucidated by spectral evidence together with physiochemical properties.

RESULT

Twelve compounds including 8 triterpenes and 4 sterols were isolated from the roots of N. latifolia, and their structures were defined as 24-en-cycloartenone (1), ursolic aldehyde (2), quinovic acid (3), rotundic acid (4), 3beta,19alpha,23,24-tetrahydroxyurs-12-en-28-oic acid (5), pyrocincholic acid 3beta-O-beta-D-fucopyranoside (6), quinovic acid 3beta-O-beta-D-glucopyranoside (7), quinovic acid-3b-O-D-glucopyranosyl-(28-->1)-beta-D-glucopyranosyl ester (8), beta-sitosterol (9), stigmastan-3,6-dione (10), stigmast-4-en-6beta-ol-3-one (11) and daucosterol (12) .

CONCLUSION

All compounds except for 4,9, andl2 are isolated from this plant for the fist time, while compounds 2, 6, 10, and 11 are isolated from the genus Nauclea for the first time.

Authors+Show Affiliations

Key Laboratory of Modern Chinese Medicines, China Pharmaceutical University, Ministry of Education, Research Department of Pharmacognosy, China Pharmaceutical University, Nanjing 211198, China.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article

Language

chi

PubMed ID

22256756

Citation

Wang, Ling, et al. "[Triterpenes and Sterols From Nauclea Latifolia]." Zhongguo Zhong Yao Za Zhi = Zhongguo Zhongyao Zazhi = China Journal of Chinese Materia Medica, vol. 36, no. 18, 2011, pp. 2511-4.
Wang L, Zhang C, Layba M, et al. [Triterpenes and sterols from Nauclea latifolia]. Zhongguo Zhong Yao Za Zhi. 2011;36(18):2511-4.
Wang, L., Zhang, C., Layba, M., & Zhang, M. (2011). [Triterpenes and sterols from Nauclea latifolia]. Zhongguo Zhong Yao Za Zhi = Zhongguo Zhongyao Zazhi = China Journal of Chinese Materia Medica, 36(18), 2511-4.
Wang L, et al. [Triterpenes and Sterols From Nauclea Latifolia]. Zhongguo Zhong Yao Za Zhi. 2011;36(18):2511-4. PubMed PMID: 22256756.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Triterpenes and sterols from Nauclea latifolia]. AU - Wang,Ling, AU - Zhang,Chaofeng, AU - Layba,Mara, AU - Zhang,Mian, PY - 2012/1/20/entrez PY - 2012/1/20/pubmed PY - 2012/2/14/medline SP - 2511 EP - 4 JF - Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica JO - Zhongguo Zhong Yao Za Zhi VL - 36 IS - 18 N2 - OBJECTIVE: To investigate the chemical constituents of Nauclea latifolia, which is an African folk medicine and collected from Guinea. METHOD: The chemical constituents were isolated by silica gel and Sephadex LH-20 column chromatographies, and structurally elucidated by spectral evidence together with physiochemical properties. RESULT: Twelve compounds including 8 triterpenes and 4 sterols were isolated from the roots of N. latifolia, and their structures were defined as 24-en-cycloartenone (1), ursolic aldehyde (2), quinovic acid (3), rotundic acid (4), 3beta,19alpha,23,24-tetrahydroxyurs-12-en-28-oic acid (5), pyrocincholic acid 3beta-O-beta-D-fucopyranoside (6), quinovic acid 3beta-O-beta-D-glucopyranoside (7), quinovic acid-3b-O-D-glucopyranosyl-(28-->1)-beta-D-glucopyranosyl ester (8), beta-sitosterol (9), stigmastan-3,6-dione (10), stigmast-4-en-6beta-ol-3-one (11) and daucosterol (12) . CONCLUSION: All compounds except for 4,9, andl2 are isolated from this plant for the fist time, while compounds 2, 6, 10, and 11 are isolated from the genus Nauclea for the first time. SN - 1001-5302 UR - https://www.unboundmedicine.com/medline/citation/22256756/[Triterpenes_and_sterols_from_Nauclea_latifolia]_ DB - PRIME DP - Unbound Medicine ER -