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Verrucous carcinoma of the esophagus: a rare variant of squamous cell carcinoma for which a preoperative diagnosis can be a difficult one to make.
J La State Med Soc. 2011 Sep-Oct; 163(5):251-3.JL

Abstract

Verrucous carcinoma of the esophagus is an extremely rare entity. It is associated with severe epithelial hyperplasia and parakeratosis of the epithelial layers. Superficial biopsies are usually falsely negative for malignant cells, as the biopsied mucosa usually demonstrates the hyperplastic epithelium. The tumor spread is through submucosal and paraesophageal infiltration. Endoscopically, verrucous carcinoma appears as a wartlike, exophytic lesion, hence the name verrucous. The diagnosis can be difficult to make, even after repeated endoscopic biopsies. We report a rare case of verrucous carcinoma of the esophagus in a 45-year-old man whose final pathologic diagnosis was confirmed only after an Ivor-Lewis esophagectomy was performed.

Authors+Show Affiliations

Division of Surgical Oncology, Louisiana State University Health Science Center, Feist-Weiller Cancer Center, Shreveport, USA.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

22272545

Citation

Chu, Quyen, et al. "Verrucous Carcinoma of the Esophagus: a Rare Variant of Squamous Cell Carcinoma for Which a Preoperative Diagnosis Can Be a Difficult One to Make." The Journal of the Louisiana State Medical Society : Official Organ of the Louisiana State Medical Society, vol. 163, no. 5, 2011, pp. 251-3.
Chu Q, Jaganmohan S, Kelly B, et al. Verrucous carcinoma of the esophagus: a rare variant of squamous cell carcinoma for which a preoperative diagnosis can be a difficult one to make. J La State Med Soc. 2011;163(5):251-3.
Chu, Q., Jaganmohan, S., Kelly, B., & Hobley, J. (2011). Verrucous carcinoma of the esophagus: a rare variant of squamous cell carcinoma for which a preoperative diagnosis can be a difficult one to make. The Journal of the Louisiana State Medical Society : Official Organ of the Louisiana State Medical Society, 163(5), 251-3.
Chu Q, et al. Verrucous Carcinoma of the Esophagus: a Rare Variant of Squamous Cell Carcinoma for Which a Preoperative Diagnosis Can Be a Difficult One to Make. J La State Med Soc. 2011;163(5):251-3. PubMed PMID: 22272545.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Verrucous carcinoma of the esophagus: a rare variant of squamous cell carcinoma for which a preoperative diagnosis can be a difficult one to make. AU - Chu,Quyen, AU - Jaganmohan,Sathya, AU - Kelly,Brandi, AU - Hobley,James, PY - 2012/1/26/entrez PY - 2012/1/26/pubmed PY - 2012/3/2/medline SP - 251 EP - 3 JF - The Journal of the Louisiana State Medical Society : official organ of the Louisiana State Medical Society JO - J La State Med Soc VL - 163 IS - 5 N2 - Verrucous carcinoma of the esophagus is an extremely rare entity. It is associated with severe epithelial hyperplasia and parakeratosis of the epithelial layers. Superficial biopsies are usually falsely negative for malignant cells, as the biopsied mucosa usually demonstrates the hyperplastic epithelium. The tumor spread is through submucosal and paraesophageal infiltration. Endoscopically, verrucous carcinoma appears as a wartlike, exophytic lesion, hence the name verrucous. The diagnosis can be difficult to make, even after repeated endoscopic biopsies. We report a rare case of verrucous carcinoma of the esophagus in a 45-year-old man whose final pathologic diagnosis was confirmed only after an Ivor-Lewis esophagectomy was performed. SN - 0024-6921 UR - https://www.unboundmedicine.com/medline/citation/22272545/Verrucous_carcinoma_of_the_esophagus:_a_rare_variant_of_squamous_cell_carcinoma_for_which_a_preoperative_diagnosis_can_be_a_difficult_one_to_make_ L2 - http://www.diseaseinfosearch.org/result/1077 DB - PRIME DP - Unbound Medicine ER -