Tags

Type your tag names separated by a space and hit enter

Versatile synthesis of isocoumarins and α-pyrones by ruthenium-catalyzed oxidative C-H/O-H bond cleavages.
Org Lett. 2012 Feb 03; 14(3):930-3.OL

Abstract

An inexpensive cationic ruthenium(II) catalyst enabled the expedient synthesis of isocoumarins through oxidative annulations of alkynes by benzoic acids. This C-H/O-H bond functionalization process also proved applicable to the preparation of α-pyrones and was shown to proceed by rate-limiting C-H bond ruthenation.

Links

Publisher Full Text (DOI)

Authors+Show Affiliations

Ackermann L
Institut für Organische und Biomolekulare Chemie, Georg-August-Universität, Tammannstrasse 2, 37077 Göttingen, Germany. Lutz.Ackermann@chemie.uni-goettingen.de
Pospech J
No affiliation info available
Graczyk K
No affiliation info available
Rauch K
No affiliation info available

MeSH

CatalysisIsocoumarinsMolecular StructureOxidation-ReductionPyronesRuthenium

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

22273364

Citation

Ackermann, Lutz, et al. "Versatile Synthesis of Isocoumarins and Α-pyrones By Ruthenium-catalyzed Oxidative C-H/O-H Bond Cleavages." Organic Letters, vol. 14, no. 3, 2012, pp. 930-3.
Ackermann L, Pospech J, Graczyk K, et al. Versatile synthesis of isocoumarins and α-pyrones by ruthenium-catalyzed oxidative C-H/O-H bond cleavages. Org Lett. 2012;14(3):930-3.
Ackermann, L., Pospech, J., Graczyk, K., & Rauch, K. (2012). Versatile synthesis of isocoumarins and α-pyrones by ruthenium-catalyzed oxidative C-H/O-H bond cleavages. Organic Letters, 14(3), 930-3. https://doi.org/10.1021/ol2034614
Ackermann L, et al. Versatile Synthesis of Isocoumarins and Α-pyrones By Ruthenium-catalyzed Oxidative C-H/O-H Bond Cleavages. Org Lett. 2012 Feb 3;14(3):930-3. PubMed PMID: 22273364.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Versatile synthesis of isocoumarins and α-pyrones by ruthenium-catalyzed oxidative C-H/O-H bond cleavages. AU - Ackermann,Lutz, AU - Pospech,Jola, AU - Graczyk,Karolina, AU - Rauch,Karsten, Y1 - 2012/01/24/ PY - 2012/1/26/entrez PY - 2012/1/26/pubmed PY - 2012/5/5/medline SP - 930 EP - 3 JF - Organic letters JO - Org Lett VL - 14 IS - 3 N2 - An inexpensive cationic ruthenium(II) catalyst enabled the expedient synthesis of isocoumarins through oxidative annulations of alkynes by benzoic acids. This C-H/O-H bond functionalization process also proved applicable to the preparation of α-pyrones and was shown to proceed by rate-limiting C-H bond ruthenation. SN - 1523-7052 UR - https://www.unboundmedicine.com/medline/citation/22273364/Versatile_synthesis_of_isocoumarins_and_α_pyrones_by_ruthenium_catalyzed_oxidative_C_H/O_H_bond_cleavages_ L2 - https://doi.org/10.1021/ol2034614 DB - PRIME DP - Unbound Medicine ER -