Tags

Type your tag names separated by a space and hit enter

[Venous constriction by local administration of ruscus extract].
Fortschr Med. 1990 Aug 20; 108(24):473-6.FM

Abstract

The venoconstrictive action of the topical application of Ruscus extract was evaluated in a randomized, double-blind study involving 18 healthy volunteers, using duplex B-scan ultrasonography. Within 2 1/2 hours of the application of 4 to 6 g of a cream containing 64 to 96 mg Ruscus extract, the diameter of the femoral vein decreased by an average (median) of 1.25 mm, while placebo (base of the cream) was associated with a diameter increase of 0.5 mm (means) (p = 0.014). The decrease in venous diameter reflects good percutaneous absorption of the active substance. To date, venoconstrictive action has been demonstrable only indirectly with the aid of plethysmographic methods; it has now been measured directly under orthostatic conditions.

Authors

No affiliation info available

Pub Type(s)

Clinical Trial
English Abstract
Journal Article
Randomized Controlled Trial

Language

ger

PubMed ID

2227746

Citation

Berg, D. "[Venous Constriction By Local Administration of Ruscus Extract]." Fortschritte Der Medizin, vol. 108, no. 24, 1990, pp. 473-6.
Berg D. [Venous constriction by local administration of ruscus extract]. Fortschr Med. 1990;108(24):473-6.
Berg, D. (1990). [Venous constriction by local administration of ruscus extract]. Fortschritte Der Medizin, 108(24), 473-6.
Berg D. [Venous Constriction By Local Administration of Ruscus Extract]. Fortschr Med. 1990 Aug 20;108(24):473-6. PubMed PMID: 2227746.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Venous constriction by local administration of ruscus extract]. A1 - Berg,D, PY - 1990/8/20/pubmed PY - 1990/8/20/medline PY - 1990/8/20/entrez SP - 473 EP - 6 JF - Fortschritte der Medizin JO - Fortschr Med VL - 108 IS - 24 N2 - The venoconstrictive action of the topical application of Ruscus extract was evaluated in a randomized, double-blind study involving 18 healthy volunteers, using duplex B-scan ultrasonography. Within 2 1/2 hours of the application of 4 to 6 g of a cream containing 64 to 96 mg Ruscus extract, the diameter of the femoral vein decreased by an average (median) of 1.25 mm, while placebo (base of the cream) was associated with a diameter increase of 0.5 mm (means) (p = 0.014). The decrease in venous diameter reflects good percutaneous absorption of the active substance. To date, venoconstrictive action has been demonstrable only indirectly with the aid of plethysmographic methods; it has now been measured directly under orthostatic conditions. SN - 0015-8178 UR - https://www.unboundmedicine.com/medline/citation/2227746/[Venous_constriction_by_local_administration_of_ruscus_extract]_ DB - PRIME DP - Unbound Medicine ER -