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Spontaneous diabetes in BB rats: evidence for insulin dependent liver microsomal delta 6 and delta 5 desaturase activities.
Horm Metab Res. 1990 Aug; 22(8):405-7.HM

Abstract

We studied linoleic acid delta 5 and dihomo-gamma-linolenic acid delta 5 desaturations, and fatty acid composition, of liver microsomes in the insulin-dependent spontaneously diabetic adult female BB rat. These desaturations were defective along the normo- and hyper-glycemic period and restored during the hypoglycemic period which followed the insulin injection to the diabetic rats. The fatty acid composition of BB rats microsomes was not consistent with the desaturase activities at the different periods of glycemia, probably because other factors than desaturation impairments were involved in the evolution of fatty acid composition.

Authors+Show Affiliations

Laboratoire de Physiologie Animale et de la Nutrition, Faculté des Sciences Mirande, Dijon, France.No affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

2227799

Citation

Mimouni, V, and J P. Poisson. "Spontaneous Diabetes in BB Rats: Evidence for Insulin Dependent Liver Microsomal Delta 6 and Delta 5 Desaturase Activities." Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Metabolisme, vol. 22, no. 8, 1990, pp. 405-7.
Mimouni V, Poisson JP. Spontaneous diabetes in BB rats: evidence for insulin dependent liver microsomal delta 6 and delta 5 desaturase activities. Horm Metab Res. 1990;22(8):405-7.
Mimouni, V., & Poisson, J. P. (1990). Spontaneous diabetes in BB rats: evidence for insulin dependent liver microsomal delta 6 and delta 5 desaturase activities. Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Metabolisme, 22(8), 405-7.
Mimouni V, Poisson JP. Spontaneous Diabetes in BB Rats: Evidence for Insulin Dependent Liver Microsomal Delta 6 and Delta 5 Desaturase Activities. Horm Metab Res. 1990;22(8):405-7. PubMed PMID: 2227799.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Spontaneous diabetes in BB rats: evidence for insulin dependent liver microsomal delta 6 and delta 5 desaturase activities. AU - Mimouni,V, AU - Poisson,J P, PY - 1990/8/1/pubmed PY - 1990/8/1/medline PY - 1990/8/1/entrez SP - 405 EP - 7 JF - Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme JO - Horm Metab Res VL - 22 IS - 8 N2 - We studied linoleic acid delta 5 and dihomo-gamma-linolenic acid delta 5 desaturations, and fatty acid composition, of liver microsomes in the insulin-dependent spontaneously diabetic adult female BB rat. These desaturations were defective along the normo- and hyper-glycemic period and restored during the hypoglycemic period which followed the insulin injection to the diabetic rats. The fatty acid composition of BB rats microsomes was not consistent with the desaturase activities at the different periods of glycemia, probably because other factors than desaturation impairments were involved in the evolution of fatty acid composition. SN - 0018-5043 UR - https://www.unboundmedicine.com/medline/citation/2227799/Spontaneous_diabetes_in_BB_rats:_evidence_for_insulin_dependent_liver_microsomal_delta_6_and_delta_5_desaturase_activities_ L2 - http://www.thieme-connect.com/DOI/DOI?10.1055/s-2007-1004934 DB - PRIME DP - Unbound Medicine ER -