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Comparison of the prognostic predictive value of the TIMI, PAMI, CADILLAC, and GRACE risk scores in STEACS undergoing primary or rescue PCI.
Rev Esp Cardiol (Engl Ed). 2012 Mar; 65(3):227-33.RE

Abstract

INTRODUCTION AND OBJECTIVES

We sought to compare the predictive value of the Thrombolysis In Myocardial Infarction (TIMI), Controlled Abciximab and Device Investigation to Lower Late Angioplasty Complications (CADILLAC), Primary Angioplasty in Myocardial Infarction (PAMI), and Global Registry for Acute Coronary Events (GRACE) scores for the outcome of ST-segment elevation acute coronary syndrome undergoing urgent percutaneous coronary intervention.

METHODS

We performed a retrospective analysis of a cohort composed of all consecutive patients with ST-segment elevation acute coronary syndrome treated by urgent percutaneous coronary intervention between 2006 and 2010 (n=1503). TIMI, PAMI, CADILLAC, and GRACE risk scores were calculated for each patient according to different clinical variables. We assessed the predictive accuracy of these scores for death, reinfarction, and target-vessel revascularization at 30 days and 1 year, using the C statistic, which was obtained by means of logistic regression and ROC curves.

RESULTS

The TIMI, PAMI, CADILLAC and GRACE showed an excellent predictive value for 30-day and 1-year mortality (C statistic range, 0.8-0.9), with superiority of the TIMI, CADILLAC, and GRACE risk models. The performance of these 4 scores was poor for both reinfarction and target-vessel revascularization (C statistic, 0.5-0.6).

CONCLUSIONS

The TIMI, PAMI, CADILLAC, and GRACE scores provide excellent information to stratify the risk of mortality in patients treated by percutaneous coronary intervention. The TIMI, CADILLAC, and GRACE models have higher predictive accuracy. The usefulness of these models for reinfarction and target-vessel revascularization prediction is questionable.

Authors+Show Affiliations

Unidad de Hemodinámica, Servicio de Cardiología, Complexo Hospitalario Universitario A Coruña, A Coruña, Spain.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng spa

PubMed ID

22281285

Citation

Méndez-Eirín, Elizabet, et al. "Comparison of the Prognostic Predictive Value of the TIMI, PAMI, CADILLAC, and GRACE Risk Scores in STEACS Undergoing Primary or Rescue PCI." Revista Espanola De Cardiologia (English Ed.), vol. 65, no. 3, 2012, pp. 227-33.
Méndez-Eirín E, Flores-Ríos X, García-López F, et al. Comparison of the prognostic predictive value of the TIMI, PAMI, CADILLAC, and GRACE risk scores in STEACS undergoing primary or rescue PCI. Rev Esp Cardiol (Engl Ed). 2012;65(3):227-33.
Méndez-Eirín, E., Flores-Ríos, X., García-López, F., Pérez-Pérez, A. J., Estévez-Loureiro, R., Piñón-Esteban, P., Aldama-López, G., Salgado-Fernández, J., Calviño-Santos, R. A., Vázquez Rodríguez, J. M., Vázquez-González, N., & Castro-Beiras, A. (2012). Comparison of the prognostic predictive value of the TIMI, PAMI, CADILLAC, and GRACE risk scores in STEACS undergoing primary or rescue PCI. Revista Espanola De Cardiologia (English Ed.), 65(3), 227-33. https://doi.org/10.1016/j.recesp.2011.10.019
Méndez-Eirín E, et al. Comparison of the Prognostic Predictive Value of the TIMI, PAMI, CADILLAC, and GRACE Risk Scores in STEACS Undergoing Primary or Rescue PCI. Rev Esp Cardiol (Engl Ed). 2012;65(3):227-33. PubMed PMID: 22281285.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Comparison of the prognostic predictive value of the TIMI, PAMI, CADILLAC, and GRACE risk scores in STEACS undergoing primary or rescue PCI. AU - Méndez-Eirín,Elizabet, AU - Flores-Ríos,Xacobe, AU - García-López,Fernando, AU - Pérez-Pérez,Alberto J, AU - Estévez-Loureiro,Rodrigo, AU - Piñón-Esteban,Pablo, AU - Aldama-López,Guillermo, AU - Salgado-Fernández,Jorge, AU - Calviño-Santos,Ramón A, AU - Vázquez Rodríguez,José M, AU - Vázquez-González,Nicolás, AU - Castro-Beiras,Alfonso, Y1 - 2012/01/26/ PY - 2011/08/05/received PY - 2011/10/24/accepted PY - 2012/1/28/entrez PY - 2012/1/28/pubmed PY - 2012/7/3/medline SP - 227 EP - 33 JF - Revista espanola de cardiologia (English ed.) JO - Rev Esp Cardiol (Engl Ed) VL - 65 IS - 3 N2 - INTRODUCTION AND OBJECTIVES: We sought to compare the predictive value of the Thrombolysis In Myocardial Infarction (TIMI), Controlled Abciximab and Device Investigation to Lower Late Angioplasty Complications (CADILLAC), Primary Angioplasty in Myocardial Infarction (PAMI), and Global Registry for Acute Coronary Events (GRACE) scores for the outcome of ST-segment elevation acute coronary syndrome undergoing urgent percutaneous coronary intervention. METHODS: We performed a retrospective analysis of a cohort composed of all consecutive patients with ST-segment elevation acute coronary syndrome treated by urgent percutaneous coronary intervention between 2006 and 2010 (n=1503). TIMI, PAMI, CADILLAC, and GRACE risk scores were calculated for each patient according to different clinical variables. We assessed the predictive accuracy of these scores for death, reinfarction, and target-vessel revascularization at 30 days and 1 year, using the C statistic, which was obtained by means of logistic regression and ROC curves. RESULTS: The TIMI, PAMI, CADILLAC and GRACE showed an excellent predictive value for 30-day and 1-year mortality (C statistic range, 0.8-0.9), with superiority of the TIMI, CADILLAC, and GRACE risk models. The performance of these 4 scores was poor for both reinfarction and target-vessel revascularization (C statistic, 0.5-0.6). CONCLUSIONS: The TIMI, PAMI, CADILLAC, and GRACE scores provide excellent information to stratify the risk of mortality in patients treated by percutaneous coronary intervention. The TIMI, CADILLAC, and GRACE models have higher predictive accuracy. The usefulness of these models for reinfarction and target-vessel revascularization prediction is questionable. SN - 1885-5857 UR - https://www.unboundmedicine.com/medline/citation/22281285/Comparison_of_the_prognostic_predictive_value_of_the_TIMI_PAMI_CADILLAC_and_GRACE_risk_scores_in_STEACS_undergoing_primary_or_rescue_PCI_ L2 - http://www.revespcardiol.org/en/linksolver/ft/pii/S0300-8932(11)00891-8 DB - PRIME DP - Unbound Medicine ER -