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[Visceral leishmaniasis (Kala-Azar) in a 3-year-old German infant (author's transl)].
Klin Padiatr. 1979 May; 191(3):311-7.KP

Abstract

The article reports on a case of visceral leishmaniasis in a 3-year-old child of German residents in Rome who had passed two vacations on the isle of Ischia. Initial signs were intermittent temperatures, marked anorexia, hepatosplenomegaly and pancytopenia, with spontaneous recovery after three weeks. At that time, leishmania serology was already positive, whereas no leishmania were found in several bone marrow preparations despite a most thorough search. During the following eight weeks, the patient had chickenpox and mumps. During the mumps, relapse of the visceral leishmaniasis occurred, associated with a dramatic increase of the hepatosplenomegaly and recurring pancytopenia. It was only now that we could discover multiple leishmania infection of the bone marrow. Subsequent therapy with sodium stibogluconate (Pentostam) was effective without any complications, and eventually cured the patient.

Authors

Wittermann C
No affiliation info available
Bienzle U
No affiliation info available
Betke K
No affiliation info available

MeSH

Antimony Sodium GluconateChickenpoxChild, PreschoolHepatomegalyHumansLeishmaniasis, VisceralMaleMumpsPancytopeniaSplenomegaly

Pub Type(s)

Case Reports
English Abstract
Journal Article

Language

ger

PubMed ID

222940

Citation

Wittermann, C, et al. "[Visceral Leishmaniasis (Kala-Azar) in a 3-year-old German Infant (author's Transl)]." Klinische Padiatrie, vol. 191, no. 3, 1979, pp. 311-7.
Wittermann C, Bienzle U, Betke K. [Visceral leishmaniasis (Kala-Azar) in a 3-year-old German infant (author's transl)]. Klin Padiatr. 1979;191(3):311-7.
Wittermann, C., Bienzle, U., & Betke, K. (1979). [Visceral leishmaniasis (Kala-Azar) in a 3-year-old German infant (author's transl)]. Klinische Padiatrie, 191(3), 311-7.
Wittermann C, Bienzle U, Betke K. [Visceral Leishmaniasis (Kala-Azar) in a 3-year-old German Infant (author's Transl)]. Klin Padiatr. 1979;191(3):311-7. PubMed PMID: 222940.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Visceral leishmaniasis (Kala-Azar) in a 3-year-old German infant (author's transl)]. AU - Wittermann,C, AU - Bienzle,U, AU - Betke,K, PY - 1979/5/1/pubmed PY - 1979/5/1/medline PY - 1979/5/1/entrez SP - 311 EP - 7 JF - Klinische Padiatrie JO - Klin Padiatr VL - 191 IS - 3 N2 - The article reports on a case of visceral leishmaniasis in a 3-year-old child of German residents in Rome who had passed two vacations on the isle of Ischia. Initial signs were intermittent temperatures, marked anorexia, hepatosplenomegaly and pancytopenia, with spontaneous recovery after three weeks. At that time, leishmania serology was already positive, whereas no leishmania were found in several bone marrow preparations despite a most thorough search. During the following eight weeks, the patient had chickenpox and mumps. During the mumps, relapse of the visceral leishmaniasis occurred, associated with a dramatic increase of the hepatosplenomegaly and recurring pancytopenia. It was only now that we could discover multiple leishmania infection of the bone marrow. Subsequent therapy with sodium stibogluconate (Pentostam) was effective without any complications, and eventually cured the patient. SN - 0300-8630 UR - https://www.unboundmedicine.com/medline/citation/222940/[Visceral_leishmaniasis__Kala_Azar__in_a_3_year_old_German_infant__author's_transl_]_ L2 - https://www.diseaseinfosearch.org/result/4166 DB - PRIME DP - Unbound Medicine ER -