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Study on the influence of cranberry extract Żuravit S·O·S(®) on the properties of uropathogenic Escherichia coli strains, their ability to form biofilm and its antioxidant properties.
Phytomedicine. 2012 Apr 15; 19(6):506-14.P

Abstract

Consumption of cranberries is known to exert positive health effects, especially against urinary tract infections. For this reason, presumably, they are widely used in folk medicine. Different aspects of cranberry phenolics activity were studied in individual papers but complex study in this matter is missing. The aim of the present study is to provide complex data concerning various aspects of cranberry extract activity. We studied the effects of subinhibitory concentrations of commercially available extract (Żuravit S·O·S(®)) against two Escherichia coli strains isolated from urine of patients with pyelonephritis. Additionally the main extract anthocyanins were characterized. The activity of extract against lipid peroxidation and its radical scavenging ability were also assessed. Żuravit S·O·S(®) decreased the hydrophobicity of one of the studied E. coli strains, reduced swimming motility and adhesion to epithelial cells of both studied strains, it also limited the ability of bacteria to form biofilm. Expression of curli was not affected by cranberry extract, the assessment of P fimbriae expression was not reliable due to extract-induced agglutination of erythrocytes. Cranberry extract caused filamentation in both studied E. coli strains. It also showed pronounced antioxidant and radical scavenging properties. The properties of the studied cranberry extract show that it could be effectively used in prevention and/or elimination of urinary tract infections, specially the recurrent ones.

Authors+Show Affiliations

Department of Medical Biology and Parasitology, Wrocław Medical University, Mikulicza-Radeckiego 9, 50-367 Wrocław, Poland.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

22306419

Citation

Wojnicz, Dorota, et al. "Study On the Influence of Cranberry Extract Żuravit S·O·S(®) On the Properties of Uropathogenic Escherichia Coli Strains, Their Ability to Form Biofilm and Its Antioxidant Properties." Phytomedicine : International Journal of Phytotherapy and Phytopharmacology, vol. 19, no. 6, 2012, pp. 506-14.
Wojnicz D, Sycz Z, Walkowski S, et al. Study on the influence of cranberry extract Żuravit S·O·S(®) on the properties of uropathogenic Escherichia coli strains, their ability to form biofilm and its antioxidant properties. Phytomedicine. 2012;19(6):506-14.
Wojnicz, D., Sycz, Z., Walkowski, S., Gabrielska, J., Aleksandra, W., Alicja, K., Anna, S. Ł., & Hendrich, A. B. (2012). Study on the influence of cranberry extract Żuravit S·O·S(®) on the properties of uropathogenic Escherichia coli strains, their ability to form biofilm and its antioxidant properties. Phytomedicine : International Journal of Phytotherapy and Phytopharmacology, 19(6), 506-14. https://doi.org/10.1016/j.phymed.2011.12.013
Wojnicz D, et al. Study On the Influence of Cranberry Extract Żuravit S·O·S(®) On the Properties of Uropathogenic Escherichia Coli Strains, Their Ability to Form Biofilm and Its Antioxidant Properties. Phytomedicine. 2012 Apr 15;19(6):506-14. PubMed PMID: 22306419.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Study on the influence of cranberry extract Żuravit S·O·S(®) on the properties of uropathogenic Escherichia coli strains, their ability to form biofilm and its antioxidant properties. AU - Wojnicz,Dorota, AU - Sycz,Zuzanna, AU - Walkowski,Stefan, AU - Gabrielska,Janina, AU - Aleksandra,Włoch, AU - Alicja,Kucharska, AU - Anna,Sokół-Łętowska, AU - Hendrich,Andrzej B, Y1 - 2012/02/04/ PY - 2011/07/13/received PY - 2011/11/21/revised PY - 2011/12/25/accepted PY - 2012/2/7/entrez PY - 2012/2/7/pubmed PY - 2012/7/31/medline SP - 506 EP - 14 JF - Phytomedicine : international journal of phytotherapy and phytopharmacology JO - Phytomedicine VL - 19 IS - 6 N2 - Consumption of cranberries is known to exert positive health effects, especially against urinary tract infections. For this reason, presumably, they are widely used in folk medicine. Different aspects of cranberry phenolics activity were studied in individual papers but complex study in this matter is missing. The aim of the present study is to provide complex data concerning various aspects of cranberry extract activity. We studied the effects of subinhibitory concentrations of commercially available extract (Żuravit S·O·S(®)) against two Escherichia coli strains isolated from urine of patients with pyelonephritis. Additionally the main extract anthocyanins were characterized. The activity of extract against lipid peroxidation and its radical scavenging ability were also assessed. Żuravit S·O·S(®) decreased the hydrophobicity of one of the studied E. coli strains, reduced swimming motility and adhesion to epithelial cells of both studied strains, it also limited the ability of bacteria to form biofilm. Expression of curli was not affected by cranberry extract, the assessment of P fimbriae expression was not reliable due to extract-induced agglutination of erythrocytes. Cranberry extract caused filamentation in both studied E. coli strains. It also showed pronounced antioxidant and radical scavenging properties. The properties of the studied cranberry extract show that it could be effectively used in prevention and/or elimination of urinary tract infections, specially the recurrent ones. SN - 1618-095X UR - https://www.unboundmedicine.com/medline/citation/22306419/Study_on_the_influence_of_cranberry_extract_Żuravit_S·O·S_®__on_the_properties_of_uropathogenic_Escherichia_coli_strains_their_ability_to_form_biofilm_and_its_antioxidant_properties_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0944-7113(12)00007-4 DB - PRIME DP - Unbound Medicine ER -