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Epidemiology of coronavirus-associated respiratory tract infections and the role of rapid diagnostic tests: a prospective study.
Hong Kong Med J. 2012 Feb; 18 Suppl 2:22-4.HK

Abstract

1. Coronaviruses accounted for 1.6% (98/6272) of respiratory tract infections based on nasopharyngeal aspirate samples. 2. HCoV-OC43 was the most common coronavirus detected,followed by HCoV-NL63, CoVHKU1,and HCoV-229E. 3. Although CoV-HKU1 infections were most often associated with the upper respiratory tract, more severe illness (pneumonia,acute bronchiolitis, and asthmatic exacerbation) may occur, especially in those with underlying disease. In young children, CoV-HKU1 infection is associated with a high rate of febrile seizures (50%). 4. CoV-HKU1 and HCoV-OC43 infections peaked in winter, in contrast to HCoV-NL63, which mainly occurred in early summer and autumn, but was absent in winter. 5. Reverse transcriptase polymerase chain reaction is useful for the rapid diagnosis of coronavirus infections.

Authors+Show Affiliations

Department of Microbiology, The University of Hong Kong, University Pathology, Queen Mary Hospital, Hong Kong SAR, China. pcywoo@hkucc.hku.hkNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

22311356

Citation

Woo, P C Y., et al. "Epidemiology of Coronavirus-associated Respiratory Tract Infections and the Role of Rapid Diagnostic Tests: a Prospective Study." Hong Kong Medical Journal = Xianggang Yi Xue Za Zhi, vol. 18 Suppl 2, 2012, pp. 22-4.
Woo PC, Yuen KY, Lau SK. Epidemiology of coronavirus-associated respiratory tract infections and the role of rapid diagnostic tests: a prospective study. Hong Kong Med J. 2012;18 Suppl 2:22-4.
Woo, P. C., Yuen, K. Y., & Lau, S. K. (2012). Epidemiology of coronavirus-associated respiratory tract infections and the role of rapid diagnostic tests: a prospective study. Hong Kong Medical Journal = Xianggang Yi Xue Za Zhi, 18 Suppl 2, 22-4.
Woo PC, Yuen KY, Lau SK. Epidemiology of Coronavirus-associated Respiratory Tract Infections and the Role of Rapid Diagnostic Tests: a Prospective Study. Hong Kong Med J. 2012;18 Suppl 2:22-4. PubMed PMID: 22311356.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Epidemiology of coronavirus-associated respiratory tract infections and the role of rapid diagnostic tests: a prospective study. AU - Woo,P C Y, AU - Yuen,K Y, AU - Lau,S K P, PY - 2012/2/8/entrez PY - 2012/2/15/pubmed PY - 2012/5/31/medline SP - 22 EP - 4 JF - Hong Kong medical journal = Xianggang yi xue za zhi JO - Hong Kong Med J VL - 18 Suppl 2 N2 - 1. Coronaviruses accounted for 1.6% (98/6272) of respiratory tract infections based on nasopharyngeal aspirate samples. 2. HCoV-OC43 was the most common coronavirus detected,followed by HCoV-NL63, CoVHKU1,and HCoV-229E. 3. Although CoV-HKU1 infections were most often associated with the upper respiratory tract, more severe illness (pneumonia,acute bronchiolitis, and asthmatic exacerbation) may occur, especially in those with underlying disease. In young children, CoV-HKU1 infection is associated with a high rate of febrile seizures (50%). 4. CoV-HKU1 and HCoV-OC43 infections peaked in winter, in contrast to HCoV-NL63, which mainly occurred in early summer and autumn, but was absent in winter. 5. Reverse transcriptase polymerase chain reaction is useful for the rapid diagnosis of coronavirus infections. SN - 1024-2708 UR - https://www.unboundmedicine.com/medline/citation/22311356/Epidemiology_of_coronavirus_associated_respiratory_tract_infections_and_the_role_of_rapid_diagnostic_tests:_a_prospective_study_ L2 - http://www.hkmj.org/abstracts/v18n1s2/22.htm DB - PRIME DP - Unbound Medicine ER -