TY - JOUR T1 - Bee-honey and yogurt: a novel mixture for treating patients with vulvovaginal candidiasis during pregnancy. AU - Abdelmonem,Allam M, AU - Rasheed,Salah M, AU - Mohamed,Abeer Sh, Y1 - 2012/02/08/ PY - 2011/10/20/received PY - 2012/01/23/accepted PY - 2012/2/9/entrez PY - 2012/2/9/pubmed PY - 2015/12/31/medline SP - 109 EP - 14 JF - Archives of gynecology and obstetrics JO - Arch Gynecol Obstet VL - 286 IS - 1 N2 - OBJECTIVE: To evaluate the clinical and mycological cure rates of a novel mixture consisting of Bee-honey and yogurt compared to local antifungal agents for treating patients with vulvo-vaginal candidiasis (VVC) during pregnancy. MATERIALS AND METHODS: This is a prospective comparative study which included 129 patients with VVC during pregnancy. The participants were allocated into study group (n = 82) who received a mixture of Bee-honey and yogurt vaginally and control group (n = 47) who received local anti-fungal agents. The Chi-square test was used to evaluate the clinical and mycological cure rates and the side-effects of both modes of therapy. RESULTS: The clinical cure rate was significantly higher in the study than the control group (87.8 vs. 72.3%, respectively) while the mycological cure rate was higher in the control than the study group (91.5 vs. 76.9%, respectively). Both types of therapy were favorably tolerated by most of the patients. Side effects were reported only in 24.3 and 29.7% of patients in group I and II, respectively (p < 0.05). CONCLUSIONS: The mixture of Bee-honey and yogurt produced a high clinical cure rate and a reasonable mycological cure rate. It can be used as a complementary or an alternative to antifungal agents especially in patients with VVC during pregnancy. SN - 1432-0711 UR - https://www.unboundmedicine.com/medline/citation/22314434/abstract/Bee_honey_and_yogurt:_a_novel_mixture_for_treating_patients_with_vulvovaginal_candidiasis_during_pregnancy_ L2 - https://dx.doi.org/10.1007/s00404-012-2242-5 DB - PRIME DP - Unbound Medicine ER -