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Endobronchial pulmonary cryptococcosis and tuberculosis in an immunocompetent host.
Singapore Med J. 2012 Feb; 53(2):e32-4.SM

Abstract

Pulmonary cryptococcosis presenting as an endobronchial tumour-like growth has rarely been described. We report the case of a male patient with normal immune function who presented with a right upper lobe mass lesion. Bronchoscopy revealed a tumour-like growth that completely occluded the anterior segment of the right upper lobe bronchus. Bronchial biopsy and computed tomography-guided lung biopsy revealed Cryptococcus, and culture of lung biopsy specimen grew Cryptococcus neoformans and Mycobacterium tuberculosis. The patient responded clinically to amphotericin B, fluconazole and anti-tuberculous therapy. However, chest radiographic response was unremarkable. A presentation of pulmonary cryptococcosis and tuberculosis, along with endobronchial tumour-like growth in the same patient, is unusual and has not been previously described.

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Authors+Show Affiliations

Thomas R
Department of Pulmonary Medicine, Christian Medical College, Vellore 632002, Tamil Nadu, India.
Christopher DJ
No affiliation info available
Balamugesh T
No affiliation info available
James P
No affiliation info available
Thomas M
No affiliation info available

MeSH

AgedCryptococcosisCryptococcus neoformansHumansLungLung Diseases, FungalMaleTuberculosis, Pulmonary

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

22337198

Citation

Thomas, R, et al. "Endobronchial Pulmonary Cryptococcosis and Tuberculosis in an Immunocompetent Host." Singapore Medical Journal, vol. 53, no. 2, 2012, pp. e32-4.
Thomas R, Christopher DJ, Balamugesh T, et al. Endobronchial pulmonary cryptococcosis and tuberculosis in an immunocompetent host. Singapore Med J. 2012;53(2):e32-4.
Thomas, R., Christopher, D. J., Balamugesh, T., James, P., & Thomas, M. (2012). Endobronchial pulmonary cryptococcosis and tuberculosis in an immunocompetent host. Singapore Medical Journal, 53(2), e32-4.
Thomas R, et al. Endobronchial Pulmonary Cryptococcosis and Tuberculosis in an Immunocompetent Host. Singapore Med J. 2012;53(2):e32-4. PubMed PMID: 22337198.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Endobronchial pulmonary cryptococcosis and tuberculosis in an immunocompetent host. AU - Thomas,R, AU - Christopher,D J, AU - Balamugesh,T, AU - James,P, AU - Thomas,M, PY - 2012/2/17/entrez PY - 2012/2/18/pubmed PY - 2012/6/20/medline SP - e32 EP - 4 JF - Singapore medical journal JO - Singapore Med J VL - 53 IS - 2 N2 - Pulmonary cryptococcosis presenting as an endobronchial tumour-like growth has rarely been described. We report the case of a male patient with normal immune function who presented with a right upper lobe mass lesion. Bronchoscopy revealed a tumour-like growth that completely occluded the anterior segment of the right upper lobe bronchus. Bronchial biopsy and computed tomography-guided lung biopsy revealed Cryptococcus, and culture of lung biopsy specimen grew Cryptococcus neoformans and Mycobacterium tuberculosis. The patient responded clinically to amphotericin B, fluconazole and anti-tuberculous therapy. However, chest radiographic response was unremarkable. A presentation of pulmonary cryptococcosis and tuberculosis, along with endobronchial tumour-like growth in the same patient, is unusual and has not been previously described. SN - 0037-5675 UR - https://www.unboundmedicine.com/medline/citation/22337198/Endobronchial_pulmonary_cryptococcosis_and_tuberculosis_in_an_immunocompetent_host_ L2 - http://smj.sma.org.sg/5302/5302cr3.pdf DB - PRIME DP - Unbound Medicine ER -