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Depression in patients with hidradenitis suppurativa.
J Eur Acad Dermatol Venereol 2013; 27(4):473-8JE

Abstract

BACKGROUND

Hidradenitis suppurativa (HS) is a chronic recurrent inflammatory skin disease with abscess formation and scarring predominantly in the inverse areas. The disease is often difficult to treat and patients experience a decreased quality of life (QoL). It is hypothesized that depression is more common in HS patients than among other dermatological patients.

OBJECTIVES

To evaluate the prevalence of depression in patients with HS.

METHODS

In total 211 HS patients were included in the study and 233 were dermatological control patients. Their QoL and depression scores were assessed using the Dermatology Life Quality Index (DLQI) and the Major Depression Inventory (MDI) questionnaires. HS severity was recorded with a questionnaire and Hurley stages were extracted from the case records.

RESULTS

The DLQI was significantly higher for HS patients than for the control patients, 8.4 ± 7.5 vs. 4.3 ± 5.6 (P < 0.0001) and correlated with Hurley stage severity scores. Mean MDI scores were significantly higher for HS patients, 11.0 vs. 7.2 (P < 0.0001). However, clinically defined depression rates according to the International Classification of Diseases, 10th edition (ICD-10) criteria were not significantly higher in HS patients compared to controls (9% vs. 6%).

CONCLUSIONS

HS is a chronic skin disease with major impact on QoL even when compared to other dermatological diseases. MDI scores in HS patients correlate with disease severity. This correlation could indicate that the MDI represents a valid measure of disease related morbidity that may serve as an outcome measure in future studies and a relevant point of intervention for individual patients.

Authors+Show Affiliations

Department of Dermatology, Deventer Hospital, Rotterdam, Netherlands.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

22339940

Citation

Onderdijk, A J., et al. "Depression in Patients With Hidradenitis Suppurativa." Journal of the European Academy of Dermatology and Venereology : JEADV, vol. 27, no. 4, 2013, pp. 473-8.
Onderdijk AJ, van der Zee HH, Esmann S, et al. Depression in patients with hidradenitis suppurativa. J Eur Acad Dermatol Venereol. 2013;27(4):473-8.
Onderdijk, A. J., van der Zee, H. H., Esmann, S., Lophaven, S., Dufour, D. N., Jemec, G. B., & Boer, J. (2013). Depression in patients with hidradenitis suppurativa. Journal of the European Academy of Dermatology and Venereology : JEADV, 27(4), pp. 473-8. doi:10.1111/j.1468-3083.2012.04468.x.
Onderdijk AJ, et al. Depression in Patients With Hidradenitis Suppurativa. J Eur Acad Dermatol Venereol. 2013;27(4):473-8. PubMed PMID: 22339940.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Depression in patients with hidradenitis suppurativa. AU - Onderdijk,A J, AU - van der Zee,H H, AU - Esmann,S, AU - Lophaven,S, AU - Dufour,D N, AU - Jemec,G B E, AU - Boer,J, Y1 - 2012/02/20/ PY - 2012/2/21/entrez PY - 2012/2/22/pubmed PY - 2013/9/10/medline SP - 473 EP - 8 JF - Journal of the European Academy of Dermatology and Venereology : JEADV JO - J Eur Acad Dermatol Venereol VL - 27 IS - 4 N2 - BACKGROUND: Hidradenitis suppurativa (HS) is a chronic recurrent inflammatory skin disease with abscess formation and scarring predominantly in the inverse areas. The disease is often difficult to treat and patients experience a decreased quality of life (QoL). It is hypothesized that depression is more common in HS patients than among other dermatological patients. OBJECTIVES: To evaluate the prevalence of depression in patients with HS. METHODS: In total 211 HS patients were included in the study and 233 were dermatological control patients. Their QoL and depression scores were assessed using the Dermatology Life Quality Index (DLQI) and the Major Depression Inventory (MDI) questionnaires. HS severity was recorded with a questionnaire and Hurley stages were extracted from the case records. RESULTS: The DLQI was significantly higher for HS patients than for the control patients, 8.4 ± 7.5 vs. 4.3 ± 5.6 (P < 0.0001) and correlated with Hurley stage severity scores. Mean MDI scores were significantly higher for HS patients, 11.0 vs. 7.2 (P < 0.0001). However, clinically defined depression rates according to the International Classification of Diseases, 10th edition (ICD-10) criteria were not significantly higher in HS patients compared to controls (9% vs. 6%). CONCLUSIONS: HS is a chronic skin disease with major impact on QoL even when compared to other dermatological diseases. MDI scores in HS patients correlate with disease severity. This correlation could indicate that the MDI represents a valid measure of disease related morbidity that may serve as an outcome measure in future studies and a relevant point of intervention for individual patients. SN - 1468-3083 UR - https://www.unboundmedicine.com/medline/citation/22339940/Depression_in_patients_with_hidradenitis_suppurativa_ L2 - https://doi.org/10.1111/j.1468-3083.2012.04468.x DB - PRIME DP - Unbound Medicine ER -