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[Field observation on the effect of low-sodium and high-potassium salt substitute on blood pressure in the rural community-based population in China].
Zhonghua Liu Xing Bing Xue Za Zhi. 2011 Sep; 32(9):859-63.ZL

Abstract

OBJECTIVE

To investigate the effect of commercial low-sodium and high-potassium salt substitutes on blood pressure in the rural community-based population in China.

METHODS

We conducted a quasi-experiment on 411 adults, who were 30 to 60 years of age, in 2 rural communities from Laiwu city in Shandong province of China on data from blood pressure screening. The subjects were divided into 2 groups: high blood pressure (HBP) and non-HBP (NHBP). Both groups and their family members took a low-sodium and high-potassium salt substitute for 3 months to replace the normal salt in their bodies. Blood pressure (BP) and 24-hour urinary sodium and potassium were measured regularly in the 2 groups.

RESULTS

There was a continuously decreasing trend for BP at the end of the first month. Three months later, the mean BP decreased by 7.4 mm Hg (1 mm Hg = 0.133 kPa, t = 10.096, P = 0.000) for SBP and 3.8 mm Hg (t = 8.017, P = 0.000) for DBP in the HBP group, when compared to a 1.2 mm Hg (t = 2.507, P = 0.007) decrease on SBP and 1.0 mm Hg (t = 2.987, P = 0.002) on DBP in the NHBP group. The mean urinary sodium had a decrease of 15.5 mmol/24 h (t = 1.803, P = 0.037), but the urinary potassium increased by 4.2 mmol/24 h (t' = 2.132, P = 0.018). The result of urinary sodium appeared to be as follows: potassium ratio (Na(+)/K(+)) decreased by 1.2 (t = 2.786, P = 0.003) in the HBP group. However, in NHBP group, the mean urinary sodium decreased by 1.7 mmol/24 h (t = 0.211, P = 0.417) and urinary potassium increased by 3.7 mmol/24 h (t' = 2.207, P = 0.015), together with the decrease of Na(+)/K(+) by 0.7 (t = 1.818, P = 0.036).

CONCLUSION

Results from our study clearly demonstrated that the intake of low-sodium and high-potassium salt substitute could effectively reduce the BP with good compliance among adults in the rural community-based population in China. This was an effective but non-medical method to prevent and control the high blood pressure.

Authors+Show Affiliations

Institute of Epidemiology and Health Statistics, School of Public Health, Shandong University, Jinan 250012, China.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article
Research Support, Non-U.S. Gov't

Language

chi

PubMed ID

22340870

Citation

Zhang, Gao-hui, et al. "[Field Observation On the Effect of Low-sodium and High-potassium Salt Substitute On Blood Pressure in the Rural Community-based Population in China]." Zhonghua Liu Xing Bing Xue Za Zhi = Zhonghua Liuxingbingxue Zazhi, vol. 32, no. 9, 2011, pp. 859-63.
Zhang GH, Ma JX, Guo XL, et al. [Field observation on the effect of low-sodium and high-potassium salt substitute on blood pressure in the rural community-based population in China]. Zhonghua Liu Xing Bing Xue Za Zhi. 2011;32(9):859-63.
Zhang, G. H., Ma, J. X., Guo, X. L., Dong, J., Chen, X., Zhang, J. Y., Su, J. Y., Tang, J. L., & Xu, A. Q. (2011). [Field observation on the effect of low-sodium and high-potassium salt substitute on blood pressure in the rural community-based population in China]. Zhonghua Liu Xing Bing Xue Za Zhi = Zhonghua Liuxingbingxue Zazhi, 32(9), 859-63.
Zhang GH, et al. [Field Observation On the Effect of Low-sodium and High-potassium Salt Substitute On Blood Pressure in the Rural Community-based Population in China]. Zhonghua Liu Xing Bing Xue Za Zhi. 2011;32(9):859-63. PubMed PMID: 22340870.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Field observation on the effect of low-sodium and high-potassium salt substitute on blood pressure in the rural community-based population in China]. AU - Zhang,Gao-hui, AU - Ma,Ji-xiang, AU - Guo,Xiao-lei, AU - Dong,Jing, AU - Chen,Xi, AU - Zhang,Ji-yu, AU - Su,Jun-ying, AU - Tang,Jun-li, AU - Xu,Ai-qiang, PY - 2012/2/21/entrez PY - 2012/2/22/pubmed PY - 2014/1/10/medline SP - 859 EP - 63 JF - Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi JO - Zhonghua Liu Xing Bing Xue Za Zhi VL - 32 IS - 9 N2 - OBJECTIVE: To investigate the effect of commercial low-sodium and high-potassium salt substitutes on blood pressure in the rural community-based population in China. METHODS: We conducted a quasi-experiment on 411 adults, who were 30 to 60 years of age, in 2 rural communities from Laiwu city in Shandong province of China on data from blood pressure screening. The subjects were divided into 2 groups: high blood pressure (HBP) and non-HBP (NHBP). Both groups and their family members took a low-sodium and high-potassium salt substitute for 3 months to replace the normal salt in their bodies. Blood pressure (BP) and 24-hour urinary sodium and potassium were measured regularly in the 2 groups. RESULTS: There was a continuously decreasing trend for BP at the end of the first month. Three months later, the mean BP decreased by 7.4 mm Hg (1 mm Hg = 0.133 kPa, t = 10.096, P = 0.000) for SBP and 3.8 mm Hg (t = 8.017, P = 0.000) for DBP in the HBP group, when compared to a 1.2 mm Hg (t = 2.507, P = 0.007) decrease on SBP and 1.0 mm Hg (t = 2.987, P = 0.002) on DBP in the NHBP group. The mean urinary sodium had a decrease of 15.5 mmol/24 h (t = 1.803, P = 0.037), but the urinary potassium increased by 4.2 mmol/24 h (t' = 2.132, P = 0.018). The result of urinary sodium appeared to be as follows: potassium ratio (Na(+)/K(+)) decreased by 1.2 (t = 2.786, P = 0.003) in the HBP group. However, in NHBP group, the mean urinary sodium decreased by 1.7 mmol/24 h (t = 0.211, P = 0.417) and urinary potassium increased by 3.7 mmol/24 h (t' = 2.207, P = 0.015), together with the decrease of Na(+)/K(+) by 0.7 (t = 1.818, P = 0.036). CONCLUSION: Results from our study clearly demonstrated that the intake of low-sodium and high-potassium salt substitute could effectively reduce the BP with good compliance among adults in the rural community-based population in China. This was an effective but non-medical method to prevent and control the high blood pressure. SN - 0254-6450 UR - https://www.unboundmedicine.com/medline/citation/22340870/[Field_observation_on_the_effect_of_low_sodium_and_high_potassium_salt_substitute_on_blood_pressure_in_the_rural_community_based_population_in_China]_ DB - PRIME DP - Unbound Medicine ER -