Tags

Type your tag names separated by a space and hit enter

Zinc, copper, iron, and chromium concentrations in young patients with type 2 diabetes mellitus.
Biol Trace Elem Res. 2012 Aug; 148(2):161-4.BT

Abstract

Homeostasis of trace elements can be disrupted by diabetes mellitus. On the other hand, disturbance in trace element status in diabetes mellitus may contribute to the insulin resistance and development of diabetic complications. The aim of present study was to compare the concentration of essential trace elements, zinc, copper, iron, and chromium in serum of patients who have type 2 diabetes mellitus (n = 20) with those of nondiabetic control subjects (n = 20). The serum concentrations of zinc, copper, iron, and chromium were measured by means of an atomic absorption spectrophotometer (Shimadzu AA 670, Kyoto, Japan) after acid digestion. The results of this study showed that the mean values of zinc, copper, and chromium were significantly lower in the serum of patients with diabetes as compared to the control subjects (P < 0.05). Our results show that deficiency of some essential trace elements may play a role in the development of diabetes mellitus.

Authors+Show Affiliations

Department of Biochemistry, School of Veterinary Medicine, Shiraz University, Shiraz 71345-1731, Iran. mehdi.basaki@gmail.comNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

22351156

Citation

Basaki, M, et al. "Zinc, Copper, Iron, and Chromium Concentrations in Young Patients With Type 2 Diabetes Mellitus." Biological Trace Element Research, vol. 148, no. 2, 2012, pp. 161-4.
Basaki M, Saeb M, Nazifi S, et al. Zinc, copper, iron, and chromium concentrations in young patients with type 2 diabetes mellitus. Biol Trace Elem Res. 2012;148(2):161-4.
Basaki, M., Saeb, M., Nazifi, S., & Shamsaei, H. A. (2012). Zinc, copper, iron, and chromium concentrations in young patients with type 2 diabetes mellitus. Biological Trace Element Research, 148(2), 161-4. https://doi.org/10.1007/s12011-012-9360-6
Basaki M, et al. Zinc, Copper, Iron, and Chromium Concentrations in Young Patients With Type 2 Diabetes Mellitus. Biol Trace Elem Res. 2012;148(2):161-4. PubMed PMID: 22351156.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Zinc, copper, iron, and chromium concentrations in young patients with type 2 diabetes mellitus. AU - Basaki,M, AU - Saeb,M, AU - Nazifi,S, AU - Shamsaei,H A, Y1 - 2012/02/21/ PY - 2012/01/14/received PY - 2012/02/07/accepted PY - 2012/2/22/entrez PY - 2012/2/22/pubmed PY - 2013/1/1/medline SP - 161 EP - 4 JF - Biological trace element research JO - Biol Trace Elem Res VL - 148 IS - 2 N2 - Homeostasis of trace elements can be disrupted by diabetes mellitus. On the other hand, disturbance in trace element status in diabetes mellitus may contribute to the insulin resistance and development of diabetic complications. The aim of present study was to compare the concentration of essential trace elements, zinc, copper, iron, and chromium in serum of patients who have type 2 diabetes mellitus (n = 20) with those of nondiabetic control subjects (n = 20). The serum concentrations of zinc, copper, iron, and chromium were measured by means of an atomic absorption spectrophotometer (Shimadzu AA 670, Kyoto, Japan) after acid digestion. The results of this study showed that the mean values of zinc, copper, and chromium were significantly lower in the serum of patients with diabetes as compared to the control subjects (P < 0.05). Our results show that deficiency of some essential trace elements may play a role in the development of diabetes mellitus. SN - 1559-0720 UR - https://www.unboundmedicine.com/medline/citation/22351156/Zinc_copper_iron_and_chromium_concentrations_in_young_patients_with_type_2_diabetes_mellitus_ L2 - https://dx.doi.org/10.1007/s12011-012-9360-6 DB - PRIME DP - Unbound Medicine ER -