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Lacrimal canalicular duct scarring in patients with lichen planus.
Arch Dermatol. 2012 Feb; 148(2):224-7.AD

Abstract

BACKGROUND

Lichen planus (LP) is a mucocutaneous inflammatory disease that affects multiple sites, including the skin, oral cavity, vulva, and vagina and can result in scarring and stricture formation. It has also been shown to cause lacrimal canalicular blockage in a series of patients attending an ophthalmology clinic. We describe a cohort of women with vulvovaginal LP who also had signs of lacrimal canalicular scarring on examination.

OBSERVATIONS

We report 9 cases of LP with scarring of the conjunctiva around the lacrimal ducts. Seven of 9 women had symptoms of epiphora, and in 2 women lacrimal canalicular scarring was an incidental finding. Seven of 9 cases were diagnosed by an ophthalmologist. All women had biopsy-proven LP at 1 mucocutaneous site each. Seven of 9 women had vulvovaginalgingival syndrome, which is a subgroup of severe erosive LP.

CONCLUSIONS

Given the strong association between erosive mucocutaneous LP and multisite scarring sequelae, it is not unexpected that ocular inflammation may lead to lacrimal duct stenosis. We believe that this complication has been underreported among patients with LP and that an ophthalmological history and examination of the punctum of the lacrimal duct should be sought, especially in patients with the erosive subtype of LP.

Authors+Show Affiliations

St. John's Institute of Dermatology, Guy's and St Thomas' National Health Service Foundation Trust, Westminster Bridge Road, London SE1 7EH, England. naomi.webber@doctors.org.ukNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

22351823

Citation

Webber, Naomi K., et al. "Lacrimal Canalicular Duct Scarring in Patients With Lichen Planus." Archives of Dermatology, vol. 148, no. 2, 2012, pp. 224-7.
Webber NK, Setterfield JF, Lewis FM, et al. Lacrimal canalicular duct scarring in patients with lichen planus. Arch Dermatol. 2012;148(2):224-7.
Webber, N. K., Setterfield, J. F., Lewis, F. M., & Neill, S. M. (2012). Lacrimal canalicular duct scarring in patients with lichen planus. Archives of Dermatology, 148(2), 224-7. https://doi.org/10.1001/archdermatol.2011.580
Webber NK, et al. Lacrimal Canalicular Duct Scarring in Patients With Lichen Planus. Arch Dermatol. 2012;148(2):224-7. PubMed PMID: 22351823.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Lacrimal canalicular duct scarring in patients with lichen planus. AU - Webber,Naomi K, AU - Setterfield,Jane F, AU - Lewis,Fiona M, AU - Neill,Sallie M, PY - 2012/2/22/entrez PY - 2012/2/22/pubmed PY - 2012/4/11/medline SP - 224 EP - 7 JF - Archives of dermatology JO - Arch Dermatol VL - 148 IS - 2 N2 - BACKGROUND: Lichen planus (LP) is a mucocutaneous inflammatory disease that affects multiple sites, including the skin, oral cavity, vulva, and vagina and can result in scarring and stricture formation. It has also been shown to cause lacrimal canalicular blockage in a series of patients attending an ophthalmology clinic. We describe a cohort of women with vulvovaginal LP who also had signs of lacrimal canalicular scarring on examination. OBSERVATIONS: We report 9 cases of LP with scarring of the conjunctiva around the lacrimal ducts. Seven of 9 women had symptoms of epiphora, and in 2 women lacrimal canalicular scarring was an incidental finding. Seven of 9 cases were diagnosed by an ophthalmologist. All women had biopsy-proven LP at 1 mucocutaneous site each. Seven of 9 women had vulvovaginalgingival syndrome, which is a subgroup of severe erosive LP. CONCLUSIONS: Given the strong association between erosive mucocutaneous LP and multisite scarring sequelae, it is not unexpected that ocular inflammation may lead to lacrimal duct stenosis. We believe that this complication has been underreported among patients with LP and that an ophthalmological history and examination of the punctum of the lacrimal duct should be sought, especially in patients with the erosive subtype of LP. SN - 1538-3652 UR - https://www.unboundmedicine.com/medline/citation/22351823/Lacrimal_canalicular_duct_scarring_in_patients_with_lichen_planus_ L2 - https://jamanetwork.com/journals/jamadermatology/fullarticle/10.1001/archdermatol.2011.580 DB - PRIME DP - Unbound Medicine ER -