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An unprotected conjugated linoleic acid supplement decreases milk production and secretion of milk components in grazing dairy ewes.
J Dairy Sci. 2012 Mar; 95(3):1437-46.JD

Abstract

Feeding conjugated linoleic acid (CLA) in a rumen-inert form to dairy ewes has been shown to increase milk production, alter milk composition, and increase the milk fat CLA content. However, few studies have tested ruminally unprotected CLA sources. The objective of this study was to evaluate the effects of an unprotected CLA supplement (29.8% of cis-9,trans-11 and 29.9% of trans-10,cis-12 isomers as methyl esters) on milk yield and composition of dairy ewes. Twenty-four lactating Lacaune ewes were used in a crossover design and received 2 dietary treatments: (1) control: basal diet containing no supplemental lipid and (2) basal diet plus CLA (30 g/d). The CLA supplement was mixed into the concentrate and fed in 2 equal meals after morning and afternoon milkings. Each experimental period consisted of 21 d: 7 d for adaptation and 14 d for data collection. The CLA supplement decreased milk fat content and yield by 31.3 and 38.0%, respectively. Milk yield and secretion of milk lactose and protein were decreased by 8.0, 9.8, and 5.6%, respectively. On the other hand, milk protein content and linear SCC score were 1.8 and 17.7% higher in ewes fed the CLA supplement. The concentration of milk fatty acids originating from de novo synthesis (<C16) was decreased by 25%, whereas the concentration of milk fatty acids taken up preformed from the plasma (>C16) was increased by 22.6% in ewes fed the CLA supplement. The CLA supplement decreased C14:1/C14:0, C16:1/C16:0, and C18:1/C18:0 desaturase indexes by 25, 18.7, and 0.1%, respectively, but increased the cis-9,trans-11 CLA/trans-11 C18:1 ratio by 8.6%. The concentrations of trans-10,cis-12 CLA and cis-9,trans-11 CLA in milk fat was 309 and 33.4% higher in ewes fed CLA. Pronounced milk fat depression coupled with the deleterious effects on milk yield, milk SCC, and secretion of all milk solids observed in ewes fed an unprotected CLA supplement is likely to be associated with high doses of trans-10,cis-12 CLA reaching the mammary gland, corroborating previous results obtained with dairy cows.

Authors+Show Affiliations

Department of Animal Science, Santa Catarina State University, Chapecó, Santa Catarina 89802-200, Brazil. deolivei2@terra.com.brNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

22365226

Citation

Oliveira, D E., et al. "An Unprotected Conjugated Linoleic Acid Supplement Decreases Milk Production and Secretion of Milk Components in Grazing Dairy Ewes." Journal of Dairy Science, vol. 95, no. 3, 2012, pp. 1437-46.
Oliveira DE, Gama MA, Fernandes D, et al. An unprotected conjugated linoleic acid supplement decreases milk production and secretion of milk components in grazing dairy ewes. J Dairy Sci. 2012;95(3):1437-46.
Oliveira, D. E., Gama, M. A., Fernandes, D., Tedeschi, L. O., & Bauman, D. E. (2012). An unprotected conjugated linoleic acid supplement decreases milk production and secretion of milk components in grazing dairy ewes. Journal of Dairy Science, 95(3), 1437-46. https://doi.org/10.3168/jds.2011-4618
Oliveira DE, et al. An Unprotected Conjugated Linoleic Acid Supplement Decreases Milk Production and Secretion of Milk Components in Grazing Dairy Ewes. J Dairy Sci. 2012;95(3):1437-46. PubMed PMID: 22365226.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - An unprotected conjugated linoleic acid supplement decreases milk production and secretion of milk components in grazing dairy ewes. AU - Oliveira,D E, AU - Gama,M A S, AU - Fernandes,D, AU - Tedeschi,L O, AU - Bauman,D E, PY - 2011/06/13/received PY - 2011/09/30/accepted PY - 2012/2/28/entrez PY - 2012/3/1/pubmed PY - 2012/7/14/medline SP - 1437 EP - 46 JF - Journal of dairy science JO - J Dairy Sci VL - 95 IS - 3 N2 - Feeding conjugated linoleic acid (CLA) in a rumen-inert form to dairy ewes has been shown to increase milk production, alter milk composition, and increase the milk fat CLA content. However, few studies have tested ruminally unprotected CLA sources. The objective of this study was to evaluate the effects of an unprotected CLA supplement (29.8% of cis-9,trans-11 and 29.9% of trans-10,cis-12 isomers as methyl esters) on milk yield and composition of dairy ewes. Twenty-four lactating Lacaune ewes were used in a crossover design and received 2 dietary treatments: (1) control: basal diet containing no supplemental lipid and (2) basal diet plus CLA (30 g/d). The CLA supplement was mixed into the concentrate and fed in 2 equal meals after morning and afternoon milkings. Each experimental period consisted of 21 d: 7 d for adaptation and 14 d for data collection. The CLA supplement decreased milk fat content and yield by 31.3 and 38.0%, respectively. Milk yield and secretion of milk lactose and protein were decreased by 8.0, 9.8, and 5.6%, respectively. On the other hand, milk protein content and linear SCC score were 1.8 and 17.7% higher in ewes fed the CLA supplement. The concentration of milk fatty acids originating from de novo synthesis (<C16) was decreased by 25%, whereas the concentration of milk fatty acids taken up preformed from the plasma (>C16) was increased by 22.6% in ewes fed the CLA supplement. The CLA supplement decreased C14:1/C14:0, C16:1/C16:0, and C18:1/C18:0 desaturase indexes by 25, 18.7, and 0.1%, respectively, but increased the cis-9,trans-11 CLA/trans-11 C18:1 ratio by 8.6%. The concentrations of trans-10,cis-12 CLA and cis-9,trans-11 CLA in milk fat was 309 and 33.4% higher in ewes fed CLA. Pronounced milk fat depression coupled with the deleterious effects on milk yield, milk SCC, and secretion of all milk solids observed in ewes fed an unprotected CLA supplement is likely to be associated with high doses of trans-10,cis-12 CLA reaching the mammary gland, corroborating previous results obtained with dairy cows. SN - 1525-3198 UR - https://www.unboundmedicine.com/medline/citation/22365226/An_unprotected_conjugated_linoleic_acid_supplement_decreases_milk_production_and_secretion_of_milk_components_in_grazing_dairy_ewes_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0022-0302(12)00101-4 DB - PRIME DP - Unbound Medicine ER -